A5101548236- Photosynthetic Processes and Mechanisms
- Plant Stress Responses and Tolerance
- Light effects on plants
- Crop Yield and Soil Fertility
- Bacterial Genetics and Biotechnology
- Algal biology and biofuel production
- Bacteriophages and microbial interactions
- Plant nutrient uptake and metabolism
- Endoplasmic Reticulum Stress and Disease
- Pluripotent Stem Cells Research
- Metabolism, Diabetes, and Cancer
- Reproductive Biology and Fertility
- Magnetic and Electromagnetic Effects
- Agricultural Science and Fertilization
- Plant Reproductive Biology
- Plant tissue culture and regeneration
- Circular RNAs in diseases
- Escherichia coli research studies
- Agronomic Practices and Intercropping Systems
- Environmental and Agricultural Sciences
- Biocrusts and Microbial Ecology
- Renal and related cancers
- Fern and Epiphyte Biology
- Kidney Stones and Urolithiasis Treatments
- Plant biochemistry and biosynthesis
Anhui Agricultural University
2023-2025
First Affiliated Hospital of Zhengzhou University
2025
Zhengzhou University
2025
Xinjiang Academy of Agricultural Sciences
2019-2024
Xinjiang Institute of Ecology and Geography
2024
Hebei Medical University
2023
China Medical University
2016-2021
Northeast Forestry University
2011-2020
Shanghai Normal University
2015-2018
Chongqing Medical University
2018
Soil salinity poses a serious threat to agriculture productivity throughout the world. Studying mechanisms of tolerance in halophytic plants will provide valuable information for engineering enhanced salt tolerance. Monocotyledonous Puccinellia tenuiflora is species that widely distributed saline-alkali soil Songnen plain northeastern China. Here we investigate molecular underlying moderate P. using combined physiological and proteomic approach. The changes biomass, inorganic ion content,...
Elevated temperatures limit plant growth and reproduction pose a growing threat to agriculture. Plant heat stress response is highly conserved fine-tuned in multiple pathways. Spinach (Spinacia oleracea L.) cold tolerant but sensitive green leafy vegetable. In this study, adaptation mechanisms spinach sibling inbred heat-tolerant line Sp75 were investigated using physiological, proteomic, phosphoproteomic approaches. The abundance patterns of 911 stress-responsive proteins, phosphorylation...
Soil alkalization severely affects crop growth and agricultural productivity. Alkali salts impose ionic, osmotic, high pH stresses on plants. The alkali tolerance molecular mechanism in roots from halophyte Puccinellia tenuiflora is still unclear. Here, the changes associated with Na2CO3 P. were assessed using physiological iTRAQ-based quantitative proteomic analyses. We set up first protein dataset containing 2,671 non-redundant proteins. Our results showed that slightly inhibited root...
Fruit-wheat intercropping is an important way to resolve the land competition between fruit and grain ensure food security. However, there little research on mechanism of wheat yield formation its response nitrogen fertilizer under long-term shading. From 2016 2017, variety “Xindong 20” was selected, four shading treatments were set: at jointing stage 10%-shading heading 25% (S1), 20%–50% (S2), 30%–75% (S3), normal light (S0) (N0: 0 kg ha−1, N1: 103.5 N2: 138 N3: 172.5 ha−1). The results...
Fern spore is a good single-cell model for studying the sophisticated molecular networks in asymmetric cell division, differentiation, and polar growth. Osmunda cinnamomea L. var. asiatica one of oldest fern species with typical separate-growing trophophyll sporophyll. The chlorophyllous spores generated from sporophyll can germinate without dormancy. In this study, ultrastructure, antioxidant enzyme activities, as well protein gene expression patterns were analyzed course germination at...
Palmella stage is critical for some unicellular algae to survive in extreme environments. The halotolerant Dunaliella salina a good single-cell model studying plant adaptation high salinity. To investigate the molecular mechanism salinity shock-induced palmella formation, we performed comprehensive physiological, proteomics and phosphoproteomics study upon formation of D. using dimethyl labeling Ti4+-immobilized metal ion affinity chromatography (IMAC) proteomic approaches. We found that 151...
Alkali-salinity exerts severe osmotic, ionic, and high-pH stresses to plants. To understand the alkali-salinity responsive mechanisms underlying photosynthetic modulation reactive oxygen species (ROS) homeostasis, physiological diverse quantitative proteomics analyses of alkaligrass (Puccinellia tenuiflora) under Na2CO3 stress were conducted. In addition, Western blot, real-time PCR, transgenic techniques applied validate proteomic results test functions Na2CO3-responsive proteins. A total...
Hepatocellular carcinoma (HCC) is a common and challenging malignancy of the digestive tract. Unfortunately, patients with advanced HCC frequently experience limited long-term benefits from current treatments, highlighting critical need for innovative therapeutic agents. The discovery development new small-molecule compounds that target tumours have become crucial aspects cancer research. In this study, we report on L-741626, compound has significant inhibitory effects HCC. Both in vivo...
The T-type Ca(2+) channel (TTCC) plays important roles in cellular excitability and regulation. In the heart, TTCC is found sinoatrial nodal (SAN) conduction cells. Cav3.1 encodes one of three types TTCCs. To date, there no report regarding regulation by β-adrenergic agonists, which topic this study. Ventricular myocytes (VMs) from double transgenic (TG) mice SAN cells wild type, knockout, or Cav3.2 knockout were used to study overexpressed native Cav3.1-mediated current (I(Ca-T(3.1)))....
C4 plants exhibit much higher CO2 assimilation rates than C{}3 under certain conditions. The specialized differentiation of mesophyll cell and bundle sheath type chloroplasts is unique to improves photosynthetic efficiency. Maize (Zea mays) an important crop model with machinery. 2DE high-throughput quantitative proteomics approaches (e.g., isobaric tags for relative absolute quantitation shotgun proteomics) have been employed investigate maize chloroplast structure function. These studies...
Non-expressor of pathogenesis-related (PR) genes1 (NPR1) is a key transcription coactivator plant basal immunity and systemic acquired resistance (SAR). Two mutant alleles, npr1-1 npr1-3, have been extensively used for dissecting the role NPR1 in various signaling pathways. However, it unknown whether npr1-3 are null mutants. Moreover, transcript levels induced two- to threefold upon pathogen infection or salicylic acid (SA) treatment, but biological relevance induction unclear. Here, we...
General control non-derepressible-2 (GCN2) is a ubiquitous protein kinase that phosphorylates the α subunit of eukaryotic initiation factor, eIF2, preventing new cycle synthesis, subsequently reducing global biosynthesis. GCN2 can also regulate response plants to biotic and abiotic stresses. In this study, two homologs, NtGCN2-1 NtGCN2-2, were cloned from Nicotiana tabacum, predicted have been derived their progenitors in N. tomentosiformis sylvestris, respectively. The phosphorylation...
Accurate evaluation of morphological and physiological traits is critical for selection wheat (Triticum aestivum L.) cultivars exhibiting high yield, which stable over different growing conditions. In order to use index based on grain quality drought tolerance in wheat, a set 145 CIMMYT Wheat Physiological Germplasm Screening Nursery lines seven local spring varieties were phenotyped evaluated yield under two irrigation regimes during the 2011 2012 seasons Xinjiang, China. The results showed...
Ureteropelvic junction obstruction (UPJO) is one of the most common causes hydronephrosis in children. This study explored effects and regulatory mechanisms circular RNA (circRNA) hsa_circRNA_0045861 (circRNA_0045861) UPJO.RNA sequencing was used to identify differentially expressed circRNAs UPJO. The circRNA_0045861 on renal cell apoptosis investigated by flow cytometry Western blot analysis. Furthermore, we bioinformatics methods predict possible target genes circRNA_0045861. Fluorescence...
The type VI secretion system (T6SS) is a apparatus widely found in pathogenic Gram-negative bacteria and important for competition among various host cell pathogenesis. Hcp core component of functional T6SS transports toxic effectors into target cells by assembling to form tube-like structures. Studies have shown that simultaneously acts as an effector influence cellular physiological activities; however, the mechanism its activity remains unclear. To investigate protein Hcp2a chicken...
Spermatophyte pollen tubes and root hairs have been used as single-cell-type model systems to understand the molecular processes underlying polar growth of plant cells. Horsetail (Equisetum arvense L.) is a perennial herb species in Equisetopsida, which creates separately growing spring summer stems its life cycle. The mature chlorophyllous spores produced from can germinate without dormancy. Here we report cellular features protein expression patterns five stages horsetail spore germination...
Leaf color change of variegated leaves from chimera species is regulated by fine-tuned molecular mechanisms. Hosta “Gold Standard” a typical with golden-green leaves, which an ideal material to investigate the mechanisms leaf variegation. In this study, margin and center regions young mature Standard”, as well plants after excess nitrogen fertilization were studied using physiological comparative proteomic approaches. We identified 31 differentially expressed proteins in various development...
The development of hepatocellular carcinoma (HCC) is a multi-step process that accumulates genetic and epigenetic alterations, including changes in circular RNA (circRNA). This study aimed to understand the alterations circRNA expression HCC metastasis explore biological functions circRNA.Ten pairs adjacent chronic hepatitis tissues from patients without venous metastases, ten with metastases were analyzed using human microarrays. Differentially expressed circRNAs then validated by...