María Célica Ysrraelit

ORCID: 0000-0003-0846-5825
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About
Contact & Profiles
Research Areas
  • Multiple Sclerosis Research Studies
  • Peripheral Neuropathies and Disorders
  • Systemic Sclerosis and Related Diseases
  • Systemic Lupus Erythematosus Research
  • Rheumatoid Arthritis Research and Therapies
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Reproductive System and Pregnancy
  • SARS-CoV-2 and COVID-19 Research
  • Vitamin D Research Studies
  • Neurogenesis and neuroplasticity mechanisms
  • Polyomavirus and related diseases
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Long-Term Effects of COVID-19
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Stress Responses and Cortisol
  • Hereditary Neurological Disorders
  • Retinal and Optic Conditions
  • Health Systems, Economic Evaluations, Quality of Life
  • Viral Infections and Immunology Research
  • RNA regulation and disease
  • Acute Lymphoblastic Leukemia research
  • Biomedical Ethics and Regulation
  • Delphi Technique in Research
  • Effects of Vibration on Health
  • vaccines and immunoinformatics approaches

Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia
2016-2025

McGill University
2023

Hospital Ramos Mejía
2022

Instituto de Neurología Cognitiva
2012-2020

Hospital Italiano de Buenos Aires
2019

Centre de Recherche Épidémiologie et Statistique
2019

Neuroscience Institute
2019

Mayo Clinic in Florida
2019

Mayo Clinic
2018

Although Vitamin D is best known as a modulator of calcium homeostasis, it also has immune modulating potential. A protective effect on multiple sclerosis supported by the reduced risk associated with sun exposure and use supplements. Moreover, high circulating levels have been lower sclerosis. In this study, we measured 1,25 (OH)2 25 (OH) in patients separated into different clinical subgroups according to disease status. addition, direct effects ex vivo CD4+ T cells myelin-peptide specific...

10.1093/brain/awp033 article EN Brain 2009-03-24

Vitamin D(3) is best known as a calcium homeostasis modulator; however, it also has immune-modulating potential. In this study, we demonstrated that immunomodulatory effects of vitamin are significantly stronger in females than males multiple sclerosis patients, well healthy subjects. Inhibition self-reactive T cell proliferation and reduction IFN-γ- IL-17-secreting numbers were considerably greater females. Furthermore, the increase IL-10-secreting CD4(+)CD25(+)FoxP3(+) regulatory parallel...

10.4049/jimmunol.1000588 article EN The Journal of Immunology 2010-09-21

Our objective was to evaluate risk of exacerbations in multiple sclerosis (MS) patients undergoing assisted reproduction technology (ART) infertility treatment.Sixteen with relapsing-remitting MS subjected 26 ART treatment cycles receiving gonadotropin-releasing hormone (GnRH) agonists and recombinant follicle-stimulating were studied prospectively. The baseline study period encompassed 12 months prior the first cycle 9 after final cycle. Neurological examinations, brain magnetic resonance...

10.1002/ana.23745 article EN Annals of Neurology 2012-10-03

In recent years, neurologists are noticing that evaluation of multiple sclerosis (MS) patients based on combining relapses, disability progression, and magnetic resonance imaging activity may be insufficient to adequately assess suboptimal responses available therapy. Inclusion quality life (QoL) parameters contribute breach this gap.To evaluate agreement levels between doctor patient perception QoL in MS.A total 700 MS 300 were invited participate a cross-sectional study by answering an...

10.3389/fneur.2017.00729 article EN cc-by Frontiers in Neurology 2018-01-11

<b>Objective:</b> To investigate hypothalamic-pituitary-adrenal axis activity in well-defined multiple sclerosis (MS) patient subgroups. <b>Methods:</b> A total of 173 patients with clinically definite MS were studied: 40 primary progressive, 41 secondary 58 relapsing-remitting remission, and 34 during acute relapse. Sixty healthy subjects served as controls. No receiving steroid or other immunomodulatory therapy. Plasma cortisol, adrenocorticotropic hormone (ACTH), dehydroepiandrosterone...

10.1212/01.wnl.0000336918.32695.6b article EN Neurology 2008-12-08

We aimed to examine treatment interventions implemented in patients experiencing neuromyelitis optica spectrum disorders (NMOSD) attacks (frequency, types, and response). Methods Retrospective study. Data on patient demographic, clinical radiological findings, administered treatments were collected. Remission status (complete [CR], partial [PR], no remission [NR]), based changes the EDSS score was evaluated before treatment, during attack, at 6 months. CR analyzed with a generalized...

10.1177/20552173211032334 article EN cc-by-nc Multiple Sclerosis Journal - Experimental Translational and Clinical 2021-07-01

Objective: Most contemporary data concerning the frequency and causes of multiple sclerosis (MS) misdiagnosis are from North America Europe with different healthcare system structure resources than countries in Latin America. We sought to determine frequency, potential contributors MS patients evaluated at an referral center Argentina. Methods: The study was a retrospective medical record review. included Clinic Fleni between April 2013 March 2021. Diagnoses prior consultation, final...

10.1177/13524585211067521 article EN Multiple Sclerosis Journal 2021-12-31

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10.1001/jamaneurol.2017.1456 article EN JAMA Neurology 2017-07-17
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