- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Glaucoma and retinal disorders
- Retinal and Optic Conditions
- Ocular Surface and Contact Lens
- Ophthalmology and Visual Impairment Studies
- Ophthalmology and Eye Disorders
- Ocular Oncology and Treatments
- Retinoids in leukemia and cellular processes
- Power Systems and Technologies
- Pneumocystis jirovecii pneumonia detection and treatment
- Tuberculosis Research and Epidemiology
- Cardiovascular Health and Risk Factors
- Machine Fault Diagnosis Techniques
- Spinal Fractures and Fixation Techniques
- Skin Protection and Aging
- Genetic and rare skin diseases.
- Glutathione Transferases and Polymorphisms
- Environmental Quality and Pollution
- Image Processing Techniques and Applications
- Cervical and Thoracic Myelopathy
- Power System Reliability and Maintenance
- Medical Image Segmentation Techniques
- Muscle Physiology and Disorders
- Cancer-related Molecular Pathways
Dalian Medical University
2011-2025
Second Affiliated Hospital of Chongqing Medical University
2011-2025
Chongqing Medical University
2011-2025
Chongqing University
2025
Nanyang Technological University
2025
Chinese University of Hong Kong, Shenzhen
2024
Xiyuan Hospital
2023
University Hospital Heidelberg
2017
Heidelberg University
2017
Huazhong University of Science and Technology
2011-2017
Background: The present study investigated the prevalence of refractive error, visual impairment, and eye diseases in school-aged children western China.Methods: survey was done a representative county (Yongchuan District, Chongqing Municipality) China. Cluster random sampling used to select aged 6 15 years. We conducted door-to-door surveys examinations including optometry, stereoscopic vision test, position movement, slit lamp examination anterior segment, retinoscopy, fundus after...
Abstract Background Retinal disorders cause substantial visual burden globally. Accurate estimates of the vision loss due to retinal diseases are pivotal inform optimal eye health care planning and allocation medical resources. The purpose this study is describe proportion impairment blindness caused by major in China. Methods A nationwide register-based vitreoretinal disease covering all 31 provinces (51 treating centres) mainland total 28 320 adults diagnosed with were included....
Purpose To evaluate and contrast the effectiveness safety of two conbercept treatment protocols—a three-dose treat-and-extend (3+T&E) regimen a pro re nata (3+PRN) regimen—in Chinese patients diagnosed with neovascular age-related macular degeneration (nAMD).
Power dispatch is essential for providing society with stable, cost-effective, and eco-friendly electricity. However, traditional methods falter as power systems grow in scale complexity, struggling multitasking, swift problem-solving, human-machine collaboration. This paper introduces Grid Artificial Intelligent Assistant (GAIA), a pioneering Large Language Model (LLM) designed to assist variety of system operational tasks, including operation adjustment, monitoring, black start scenarios....
This study aimed to develop and validate a risk nomogram prediction model based on the retinal geometry of diabetic retinopathy (DR) in patients with type 2 diabetes mellitus (T2DM) investigate its clinical application value.In this study, we collected data 410 T2DM Second Affiliated Hospital Chongqing Medical University between October 2020 March 2022. Firstly, were randomly divided into development cohort validation ratio 7:3. Then, modeling factors selected using least absolute shrinkage...
In response to the urgent demand for grid stability and complex challenges posed by renewable energy integration electricity market dynamics, power sector increasingly seeks innovative technological solutions. this context, large language models (LLMs) have become a key technology improve efficiency promote intelligent progress in with their excellent natural processing, logical reasoning, generalization capabilities. Despite potential, absence of performance evaluation benchmark LLM has...
Vertebrate skeletal muscle contraction and relaxation is a complex process that depends on Ca2+ ions to promote the interaction of actin myosin. This can be modulated by nitric oxide (NO), gas molecule synthesized endogenously (nitric synthase) NOS isoforms. At nanomolar concentrations NO activates soluble guanylate cyclase (sGC), which in turn protein kinase G via conversion GTP into cyclic GMP. Alternatively, post-translationally modifies proteins S-nitrosylation thiol group cysteine....
Power dispatch is essential for providing stable, cost-effective, and eco-friendly electricity to society. However, traditional methods falter as power systems grow in scale complexity, struggling with multitasking, swift problem-solving, human-machine collaboration. This paper introduces GAIA, the pioneering Large Language Model (LLM) tailored tasks. We have developed a novel dataset construction technique that harnesses range of data sources fine-tune GAIA optimal performance this domain....
Age-related macular degeneration (AMD) can cause vision loss or blindness in elderly. The associations between single nucleotide polymorphism (SNP) and AMD Chinese Tujia ethnic minority group are still unclear. A total of 2122 volunteers were recruited 197 them diagnosed with (either dry wet type).Then the blood specimens these patients 404 controls from remaining 1925 normal collected to detect frequencies 39 chosen SNPs. Bonferroni method was used correct P values Fisher’s exact test. mean...
To assess the effects of marginal vitamin A deficiency (MVAD) on rat Meibomian gland morphology as well retinoic acid receptor (RAR) and retinoid X (RXR) amounts localization.Eight adult female rats were randomized into MVAD normal (VAN) groups, fed A-deficient control diets, respectively, for 3 weeks before mating. At postnatal week 4 (P4w), eight newborn animals in both groups euthanized, respectively. Then, serum retinol levels analyzed. glands from P4w further assessed upon hematoxylin...
We aimed to investigate the prevalence and causes of visual impairment (VI) in an elderly Tujia ethnic rural population Southwest China. From June 1 December 31, 2018, a random cluster sampling survey was conducted among individuals aged 50 years or older areas Qianjiang District County Chongqing. The design used village-based clusters approximately equal size (1000 people). frame composed 110 including 26,527 adults older; 10 (2556 adults) were randomly selected, 2122 subjects examined....
To avoid the side effects of ocular hypertension glucocorticoid (GC) usage in eye, we must identify susceptible individuals, which exists about one-third all population. Further, majority primary open angle glaucoma (POAG) patients show this phenotype. Glucocorticoid receptor (GR) regulates C responsiveness trabecular meshwork (TM) cells. In study, single nucleotide polymorphism (SNP) genotyping was used to determine whether there are differences BclI (rs41423247) and N363S (rs6195)...
Background Cell immunologic therapy for retinoblastoma (RB)is becoming a hot research topic. Cancer-testis antigen is human immunogenic protein and used to treat some tumors. However,its effect on RB has not been investigated. Objective The present study was discuss the specific anti-tumor of cytotoxic T lymphocytes (CTL)induced by cancer-testis antigen, NY-ESO-l-sensitized dendritic cells (DCs), RB. Methods PCR performed amplify target gene fragments from NY-ESO-1 plasmids,and then were...
Abstract Background Tuberculosis (TB) has a high morbidity and mortality rate, its prevention treatment focus is on impoverished areas. The Liangshan Yi Autonomous Prefecture typical area in western China with insufficient medical resources HIV positivity. However, there have been few reports of TB drug resistance this area. Methods We collected the demographic clinical data inpatients sputum smear positive between 2015 2021 an infectious disease hospital Prefecture. Descriptive analyses...
Choroidal osteoma is a rare benign ossifying tumor of the choroid. Posterior scleritis an uncommon yet potentially sight-threatening inflammation sclera. Herein, we report case choroidal secondary to chronic posterior accompanied by literature review. Decalcification tumor, neovascularization, and retinal pigment epithelium atrophy can result in blindness. Hence, patients with recurrent need long-term follow-up; addition, be alert for complications, such as osteoma, which ultimately lead...
To evaluate factors affecting visual acuity prognosis in patients with neovascular age-related macular degeneration (nAMD) following anti-vascular endothelial growth factor (anti-VEGF) therapy via intravitreal injection and to identify baseline risk for subretinal fibrosis (SF).
The processing of image object visual sensor is a key issue in robot intelligent control. A new method for recognition based on Radon transform proposed. On the basis preprocessing, algorithm extracting shape features at different angles Transform (RT) given. To increase efficiency algorithm, two feature sets have been formed. One coarse set that formed to measure similarity between template and then are aligned. Another fine realize by matching. results some tests show robust translation,...