- Head and Neck Cancer Studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Lung Cancer Treatments and Mutations
- Inflammatory Biomarkers in Disease Prognosis
- Retinal Imaging and Analysis
- Head and Neck Surgical Oncology
- Cancer-related molecular mechanisms research
- Lung Cancer Diagnosis and Treatment
- Lung Cancer Research Studies
- Retinal and Optic Conditions
- Artificial Intelligence in Healthcare and Education
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Dyeing and Modifying Textile Fibers
- Berberine and alkaloids research
- Enzyme-mediated dye degradation
- Ultrasound Imaging and Elastography
- Radiomics and Machine Learning in Medical Imaging
- Liver physiology and pathology
- Machine Learning in Bioinformatics
- Flavonoids in Medical Research
- Esophageal Cancer Research and Treatment
- Cancer, Lipids, and Metabolism
- Management of metastatic bone disease
- Metastasis and carcinoma case studies
Guangxi Medical University
2012-2024
Third People's Hospital of Huzhou
2021-2022
Weatherford College
2021
Tumor Hospital of Guangxi Medical University
2016-2020
The Ohio State University
2019
The Ohio State University Wexner Medical Center
2019
Inner Mongolia People's Hospital
2017
Abstract Background In the development of artificial intelligence in ophthalmology, ophthalmic AI-related recognition issues are prominent, but there is a lack research into people’s familiarity with and their attitudes toward AI. This survey aims to assess medical workers’ other professional technicians’ with, toward, concerns about AI ophthalmology. Methods cross-sectional study design study. An electronic questionnaire was designed through app Questionnaire Star, sent respondents WeChat,...
Purpose: To develop a multi-RNA-based model to provide survival risk prediction for colon cancer by constructing competing endogenous RNAs (ceRNAs) network. Methods: The prognostic information and expression of the lncRNAs, miRNAs, mRNAs in specimens from Cancer Genome Atlas (TCGA) were assessed. Constructing models used differentially expressed RNAs. Kyoto Encyclopedia Genes Genomes (KEGG) analyses Gene Ontology identify functional role ceRNA network prognosis cancer. Results: Five lncRNAs...
This study explored the relationship between prognostic nutritional index (PNI) and overall survival rate (OS) in patients with nasopharyngeal carcinoma (NPC), established validated an effective nomogram to predict clinical outcomes.This included 618 newly diagnosed locoregionally advanced NPC. They were divided into training validation cohorts at a ratio of 2:1 based on random numbers. The primary endpoint this was OS, progression-free (PFS) second endpoint. A drawn from results...
Inflammatory response markers plays an important role in tumor progression. The aim of this analysis was to evaluate whether the neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte (PLR) could predict prognosis nasopharyngeal carcinoma(NPC).247 patients who underwent Intensity Modulated Radiation Therapy( IMRT )were enrolled from January 2012 December 2012. NLR, PLR were calculated peripheral blood cell counts taken at pre-treatment. Optimal cutoff values NLR determined on basis...
// Kai-Hua Chen 1 , Xiao-Dong Zhu 1,2,3 Ling Li Song Qu Zhen-Qiang Liang Xia Xin-Bin Pan Zhong-Guo and Yan-Ming Jiang Department of Radiation Oncology, Affiliated Tumor Hospital Guangxi Medical University, Cancer Institute Zhuang Autonomous Region, Nanning, Guangxi, China 2 Key Laboratory Early Prevention Treatment for Regional High Frequency (Guangxi University), Ministry Education, 3 Correspondence to: Zhu, email: Keywords : nasopharyngeal neoplasm, stage II, concurrent chemoradiotherapy,...
Abstract The TNM staging system of NPC is the most important model for survival prediction. However, this does not consider biological variability tumor itself. This study aimed to develop a nomogram predicting overall loco-regionally advanced nasopharyngeal carcinoma. 487 Patients with confimed carcinoma who underwent IMRT and chemotherapy were included in study. We established prognostic (OS) based on Cox proportional hazards model. predictive accuracy discriminative ability measured using...
We investigated the efficacy of metastatic lesion radiotherapy (MLRT) in patients with nasopharyngeal carcinoma (mNPC).
The aim of this study was to compare the 2008 Chinese and 7th edition American Joint Committee on Cancer (AJCC) staging systems for nasopharyngeal carcinoma provide proposals updating T N present system.Between January 2007 December 2012, a cohort 752 patients with biopsy-proven, newly diagnosed, non-metastatic who were treated intensity-modulated radiotherapy retrospectively analysed. Prognoses compared by stage, clinical stage according two overall survival (OS), local relapse-free (LRFS),...
Background and Aim: Nasopharyngeal carcinoma (NPC) is one of the most common cancers in Southern China, Southeast Asia. Radiotherapy main treatment for NPC. Still, about 20% patients with NPC have a recurrence. No effective serum biomarkers are available recurrent nasopharyngeal (rNPC) to date. This study aimed explore whether amyloid beta (A4) precursor protein (APP) might serve as valuable diagnostic prognostic biomarker rNPC. Methods: In previous study, tandem mass tag–based proteomic...
To assess the prognostic value of neutrophil-to-lymphocyte ratio (NLR) in stage II nasopharyngeal carcinoma (NPC).Stage (2010 UICC/AJCC staging system) NPC patients treated between January 2007 and December 2014 were retrospectively analyzed. The NLR was calculated from peripheral blood cell counts before treatment. optimal cut-off determined by receiver operating characteristic curve analysis. Survival rates compared according to value. Multivariable Cox regression analyses performed...
Diabetic retinopathy (DR) is currently one of the severe complications leading to blindness, and computer-aided, diagnosis technology-assisted DR grading has become a popular research trend especially for development deep learning methods. However, most learning-based models require large number annotations provide data guidance, it laborious experts find subtle lesion areas from fundus images, making accurate annotation more expensive than other vision tasks. In contrast, large-scale...
Purpose: Whether neoadjuvant chemotherapy (NCT) followed by concurrent chemoradiotherapy (CCRT) could improve survival in nasopharyngeal carcinoma (NPC) remains controversial especially the era of intensity-modulated radiation therapy (IMRT), and we explored role NCT for NPC patients. Patients methods: A retrospective review was conducted 255 patients treated with NCT+CCRT (n=67) or CCRT alone (n=188) based on IMRT between December 2006 2012. To control imbalance, a 1:2 match performed using...
To compare the prognostic value of lymph node ratio (LNR) and pN in patients with non-small cell lung cancer (NSCLC) undergoing surgery.
Purpose: To investigate N-staging Assessment of pretreatment Shear wave elastrography(SWE) in small cervical lymph nodes(0.5 cm ≤maximum diameter <1cm, intact capsule, no central necrosis, sCLNs) nasopharyngeal carcinoma (NPC) patients. Methods: Pathological biopsy proven 28 NPC patients with sCLNs shown magnetic resonance (MR) images and 40 target nodes were enrolled. All divided into metastasis benign node groups according to pathology. SWE was used exam the real time imaging each before...
To assess the maximal lymph nodal diameter on 8th edition American Joint Committee Cancer staging system of nasopharyngeal carcinoma (NPC).This study extracted NPC patients between 2004 and 2016 in Surveillance, Epidemiology, End Results database. Included were divided into 3 groups: ≤3 cm, >3-6 >6 cm based diameter. Cumulative survival curves 5-year overall (OS) cancer-specific (CSS) calculated using Kaplan-Meier method groups.The OS (64.0% vs 59.3%, P = .240) CSS (71.8% 67.0%, .242) groups...
Objective To compare the 7th edition of International Union Against Cancer (UICC) staging system with Chinese 2008 for nasopharyngeal carcinoma (NPC), and to provide evidence further updating system. Methods A retrospective analysis was performed among 767 patients who were pathologically newly diagnosed non-metastatic NPC treated intensity-modulated radiotherapy from 2006 2012. Based on main prognostic indices, overall survival (OS), locoregional failure-free survival(LFFS)local...
Abstract Objective To compare the 7th edition of International Union Against Cancer (UICC) and Chinese 2008 staging systems for nasopharyngeal carcinoma (NPC), to provide evidence further updates these NPC systems. Methods A retrospective analysis was carried out on 767 patients with newly diagnosed, pathologically confirmed non‐metastatic who were treated intensity‐modulated radiotherapy between 2006 2012. The prognostic value T category, N clinical stage main survival outcomes overall...
Abstract Objectives: Upper extremity dysfunction (UED) is a known side effect of breast cancer treatment. It unclear, however, to what degree radiation contributes this morbidity. We aimed characterize the level UED using patient-reported outcomes (PROs) prior to, during, and after treatment with for cancer. Our secondary aims were evaluate association pain scores. Methods: This single-institution, prospective, longitudinal cohort study patients treated The validated outcome measure, Quick...