A5100640270- Cerebrovascular and Carotid Artery Diseases
- Acute Ischemic Stroke Management
- Intracranial Aneurysms: Treatment and Complications
- Neonatal Respiratory Health Research
- Congenital Diaphragmatic Hernia Studies
- Neurological Disease Mechanisms and Treatments
- Growth Hormone and Insulin-like Growth Factors
- Pregnancy and preeclampsia studies
- Peptidase Inhibition and Analysis
- Cardiovascular Health and Disease Prevention
- Apelin-related biomedical research
- Cardiac Imaging and Diagnostics
- Pleural and Pulmonary Diseases
- Inflammasome and immune disorders
- Renin-Angiotensin System Studies
- RNA Interference and Gene Delivery
- Renal cell carcinoma treatment
- Genetic Associations and Epidemiology
- Clinical Laboratory Practices and Quality Control
- Neonatal and Maternal Infections
- S100 Proteins and Annexins
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Fungal Infections and Studies
- Brain Tumor Detection and Classification
- Dermatological and Skeletal Disorders
Sun Yat-sen University
2010-2022
The First Affiliated Hospital, Sun Yat-sen University
2010-2022
Chongqing Medical University
2022
Second Affiliated Hospital of Nanjing Medical University
2022
Yuhuangding Hospital
2018
Qingdao University
2018
Nanjing Medical University
2010-2016
Nanjing Children's Hospital
2012-2016
Anhui Medical University
2014
UCLA Health
2012
Small cell neuroendocrine carcinoma (SCNC) of the prostate is a variant form cancer that occurs de novo or as recurrent tumor in patients who received hormonal therapy for prostatic adenocarcinoma. It composed pure (NE) cells, but unlike scattered NE cells benign and adenocarcinoma are quiescent, SCNC highly proliferative aggressive, causing death months. In this study, we provide evidence interleukin 8 (IL8)–CXCR2–P53 (TP53) signaling pathway keeps quiescent state normally. While P53...
Both statins and klotho have been shown to be beneficial in vascular diseases. Interleukin- (IL-) 6 is evidenced as an indicator reflecting the stability of atherosclerotic plaque involved pathogenesis artery atherosclerosis. However, relationship between statin, klotho, IL-6 under inflammatory environment unknown. Using primary human umbilical vein endothelial cells (HUVECs), pravastatin dose-dependently induced expression contrast remarkable suppression expressions determined by qRT-PCR....
Cortical vein thrombosis (CVT) receives little attention in adult patients with cerebral venous sinus (CVST). This study aimed to investigate the clinical and radiological features of CVST concomitant CVT. From May 2009 2016, we recruited 44 (diagnosed within 1 month onset; 33.8 ± 14.0 years age, 28 males). CVT was primarily confirmed using computed tomography venography magnetic resonance imaging sequence contrast enhanced three dimensions magnetization prepared rapid acquisition gradient...
The Pediatric Reference Intervals in China (PRINCE) was initiated to establish the reference intervals (RIs) of Chinese children, as well make it possible compare variability biochemical markers among countries internationally.
BACKGROUND: Aneurysms are associated with a mortality rate of 81% or more in cases rupture. Intraluminal thrombus (ILT) is common complication aneurysms, it can greatly increase the risk Especially for some complex physicians need to consider thrombosis progression and precisely formulate treatment plan. Therefore, particularly important assess level through haemodynamics. OBJECTIVE: To analyse haemodynamic indices compare double false lumen abdominal aortic dissection aneurysm using...
MicroRNA-206 (miR-206), the homolog of which in mice is termed miR-206-3p, a muscle-specific miRNA known to be important development skeletal muscle, and involved smooth muscle innervation airway through post‑transcriptional suppression brain‑derived neurotrophic factor (Bdnf). miR‑206‑3p also expressed at significant levels adult embryonic skin; however, its functional roles skin during remain fully elucidated. In present study, spatiotemporal expression target‑gene, Bdnf, mouse were...
To evaluate the relationship between flow signal intensity of branch arteries distal to stenosis on 3-dimensional (3D) time-of-flight (TOF) magnetic resonance angiography (MRA) and risk stroke recurrence in patients with severe middle cerebral artery (MCA) trunk stenosis. We prospectively recruited 153 (mean age 62.9 ± 13.0 years, 106 males) a first ischemic or transient attack caused by MCA (70 % 99 %) confirmed 3D TOF MRA followed them for one year determine recurrence. The site was...
Although pontine infarction is the most common subtype of posterior circulation stroke, there has been little research focusing on recurrent infarction. Our study aimed to investigate factors associated with site and mechanism Patients acute isolated were enrolled followed up for one year. Lesion topography was determined by diffusion-weighted imaging. Mechanisms based lesion other vascular, cardiologic laboratory results. A total 562 patients included, 67 experiencing recurrence during...
ADAM metallopeptidase domain 29 (ADAM29) belongs to the family, is a type I integral membrane protein and secrets glycoprotein that mediates cell-cell cell-matrix interaction. Aberrant expression of ADAM29 involved in number physiological processes diversification. The purpose present study was investigate biological effect human gastric cancer (GC) specimens cell lines vitro. examined 83 GC samples 25 adjacent normal tissues using quantitative reverse transcriptase-quantitative polymerase...
A 51-year-old man was admitted due to weakness (3/5) of the right lower extremity. Brain MRI revealed acute infarcts in left anterior cerebral artery (ACA) territory (figure, A). Angiographic images demonstrated a stenotic lesion A2 segment B and C), which high-resolution as dissection D E). Although extensive assessments were conducted, underlying arteriopathy not found. Arterial is frequent cause ACA (43%),1 its diagnosis depends on angiographic examinations. Our case showed that might be...
Cathepsin S plays an important role in the pathogenesis of several cardiovascular diseases; however, relationship between serum cathepsin and cerebral infarction (CI) is still unknown. This study aimed to investigate acute phase level infarction. A total 202 stroke patients were enrolled into this study, divided (n = 140) group non‐cerebral (non‐CI, n 62). Fifty healthy individuals recruited as control group. Serum levels cystatin C measured at days 1, 7, 14 posthospitalization. Compared...
To investigate the clinical and radiologic features of patients with spontaneous cerebral arterial dissections (CADs) presenting ischemic stroke to explore effect gender age on those features.Patients admitted our center diagnosed as secondary CADs from August 2008 April 2015 were prospectively registered. Patients aged between 15 80 years old, who had acute brain infarcts within territory a major artery affected by dissection confirmed neuroradiological examinations, enrolled in study. The...
Introduction High-resolution magnetic resonance imaging (HR-MRI) is used to characterize atherosclerotic plaque. The present study aimed determine the high-risk features of basilar artery (BA) Methods Patients with advanced BA stenosis were screened. including ruptured fibrous cap (RFC), lipid core, intraplaque hemorrhage (IPH), plaque enhancement, and calcification assessed by using high-resolution MRI. relationship between acute infarction was analyzed. Results From 1 June 2014 31 December...