Ken Nagao

ORCID: 0000-0003-1021-6238
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About
Contact & Profiles
Research Areas
  • Cardiac Arrest and Resuscitation
  • Cardiac Imaging and Diagnostics
  • Mechanical Circulatory Support Devices
  • Trauma and Emergency Care Studies
  • Acute Myocardial Infarction Research
  • Lipoproteins and Cardiovascular Health
  • Heart Failure Treatment and Management
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Thermal Regulation in Medicine
  • Heart Rate Variability and Autonomic Control
  • Coronary Interventions and Diagnostics
  • Emergency and Acute Care Studies
  • Cardiac Structural Anomalies and Repair
  • Respiratory Support and Mechanisms
  • Traumatic Brain Injury Research
  • Intensive Care Unit Cognitive Disorders
  • Cardiovascular Function and Risk Factors
  • Non-Invasive Vital Sign Monitoring
  • Cardiac, Anesthesia and Surgical Outcomes
  • Cardiac electrophysiology and arrhythmias
  • Disaster Response and Management
  • Takotsubo Cardiomyopathy and Associated Phenomena
  • Fatty Acid Research and Health
  • Cardiovascular Disease and Adiposity
  • Acute Ischemic Stroke Management

Shibuya University Network
2016-2025

Nihon University
2015-2024

Surugadai Nihon University Hospital
2012-2023

Keio University
2013-2023

Tokyo Health Care University
2015-2023

The University of Tokyo
2022

Japanese Circulation Society
2011-2021

NTT Medical Center
2014-2020

The George Institute for Global Health
2019

George Institute for Global Health
2017-2019

It is unclear whether dissemination of automated external defibrillators (AEDs) in public places can improve the rate survival among patients who have had an out-of-hospital cardiac arrest.From January 1, 2005, through December 31, 2007, we conducted a prospective, population-based, observational study involving consecutive across Japan arrest and whom resuscitation was attempted by emergency responders. We evaluated effect nationwide public-access AEDs on after arrest. The primary outcome...

10.1056/nejmoa0906644 article EN New England Journal of Medicine 2010-03-17

Background— Little is known about the nationwide trend in survival of out-of-hospital cardiac arrest (OHCA) Japan and differences incidence by age group origin arrest. Methods Results— A nationwide, prospective, population-based observation covering whole population involving consecutive OHCA patients with resuscitation attempts was conducted from January 2005 to December 2009. The main outcome measure 1-month favorable neurological outcome. trends were assessed. Multiple logistic regression...

10.1161/circulationaha.112.109496 article EN Circulation 2012-10-04

Therapeutic hypothermia for comatose survivors of out-of-hospital cardiac arrest has demonstrated neurological benefits. Although early cooling during enhances efficacy in animal studies, few clinical studies are available.The 171 patients who failed to respond conventional cardiopulmonary resuscitation were studied prospectively. Patients underwent emergency bypass (CPB) plus intra-aortic balloon pumping, with subsequent percutaneous coronary intervention (PCI) if needed. Mild (34 degrees C...

10.1253/circj.cj-09-0502 article EN Circulation Journal 2009-12-25

During out-of-hospital cardiac arrest, it is unclear how long prehospital resuscitation efforts should be continued to maximize lives saved.Between 2005 and 2012, we enrolled 282 183 adult patients with bystander-witnessed arrest from the All-Japan Utstein Registry. Prehospital duration was calculated as time interval call receipt return of spontaneous circulation in cases achieving or hospital arrival not circulation. In each 4 groups stratified by initial rhythm (shockable versus...

10.1161/circulationaha.115.018788 article EN Circulation 2016-02-27

It remains unclear which is more effective to increase survival after out-of-hospital cardiac arrest in those with public-access defibrillation, bystander-initiated chest compression-only cardiopulmonary resuscitation (CPR) or conventional CPR rescue breathing.A nationwide, prospective, population-based observational study covering the whole population of Japan and involving consecutive patients attempts has been conducted since 2005. We enrolled all arrests presumed origin that were...

10.1161/circulationaha.112.109504 article EN Circulation 2012-12-10

Although chest compression-only cardiopulmonary resuscitation (CPR) is effective for adult out-of-hospital cardiac arrest (OHCA) of origin, it remains uncertain whether bystander-initiated rescue breathing has an incremental benefit OHCA noncardiac origin.A nationwide, prospective, population-based, observational study covering the whole population Japan and involving consecutive patients with emergency responder attempts was conducted from January 2005 through December 2007. The primary...

10.1161/circulationaha.109.926816 article EN Circulation 2010-07-07

The clinical features of gender differences in takotsubo cardiomyopathy (TC) remain to be determined. aim this study was evaluate the characteristics male and female patients with TC.We obtained information 368 diagnosed TC (84 male, 284 female) from Tokyo CCU Network database collected 1 January 2010 31 December 2012; is comprised 71 cardiovascular centers (Japan) metropolitan area. We attempted characterize during hospitalization, comparing TC.There were no significant apical ballooning...

10.1371/journal.pone.0136655 article EN cc-by PLoS ONE 2015-08-28

Limited data exists on ST-segment elevation myocardial infarction (STEMI) and non-STEMI (NSTEMI) managed by a well-organized cardiac care network in metropolitan area. We analyzed the Tokyo CCU database 2009-2010. Of 4329 acute (AMI) patients including STEMI (n = 3202) NSTEMI 1127), percutaneous coronary intervention (PCI) was performed 88.8 % of 70.4 patients. Mean onset-to-door door-to-balloon times were shorter than those (167 vs 233 60 145 min, respectively, p < 0.001). Coronary artery...

10.1007/s00380-015-0791-9 article EN cc-by Heart and Vessels 2016-01-12

To investigate the association between regional brain oxygen saturation (rSO2) at hospital arrival and neurological outcomes 90 days in patients with out-of-hospital cardiac arrest (OHCA).The Japan-Prediction of Outcomes post (J-POP) registry is a prospective, multicenter, cohort study to test whether rSO2 predicts after OHCA. We measured OHCA immediately using near-infrared spectrometer placed on forehead non-blinded fashion. The primary endpoint was "neurological outcomes" OHCA.EMS...

10.1016/j.resuscitation.2014.02.012 article EN cc-by-nc-sa Resuscitation 2014-03-05

We investigated whether patients with out-of-hospital cardiac arrest (OHCA) and sustained ventricular fibrillation/pulseless tachycardia (VF/pVT) or conversion to pulseless electrical activity/asystole (PEA/asystole) benefit more from extracorporeal cardiopulmonary resuscitation (ECPR).

10.1253/circj.cj-18-1257 article EN Circulation Journal 2019-03-19

Background The diagnosis of acute coronary syndrome (ACS), especially non-ST-elevation myocardial infarction and unstable angina in the emergency department (ED) still remains a challenge. Multislice computed tomography (MSCT) allows assessment not only artery stenoses occlusions, but also plaques perfusion status. Methods Results MSCT was performed 31 patients who were admitted to ED because chest pain persisting at least 30 min non-diagnostic ECG changes normal serum enzyme concentrations....

10.1253/circj.69.1047 article EN Circulation Journal 2005-01-01

Mild hypothermia is an effective therapy for patients with return of spontaneous circulation (ROSC) after out-of-hospital cardiac arrest. However, evidence the effectiveness therapeutic (TH) remains unclear.A multicenter registry in Japan (J-PULSE-HYPO study registry) was conducted to investigate TH post-resuscitation neurological dysfunction developing arrest from 14 institutions, between January 2005 and December 2009. The committee entrusted each hospital timing cooling, cooling methods,...

10.1253/circj.cj-11-0137 article EN Circulation Journal 2011-01-01

Whether temporal differences alter the clinical outcomes of patients with out-of-hospital cardiac arrest (OHCA) remains inconclusive. Furthermore, relationship between time day and resuscitation efforts is unknown.We studied adult OHCA in Survey Survivors after Out-of-Hospital Cardiac Arrest Kanto Region (SOS-KANTO) 2012 study from January to March 2013 Japan. The primary variable was 1-month survival. secondary outcome variables were prehospital in-hospital by bystanders, emergency medical...

10.1186/s13054-016-1323-4 article EN cc-by Critical Care 2016-05-06
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