A QR-coded microtaggant for the anti-counterfeiting of drugs is proposed that can provide high capacity and error-correction capability. It fabricated lithographically in a microfluidic channel with special consideration island patterns QR Code. The incorporated drug capsule (“on-dose authentication”) be read by simple smartphone Code reader application when removed from washed free drug.

Relative intensity noise (RIN) is one of the most significant factors limiting sensitivity an optical coherence tomography (OCT) system. The existing and prevalent theory being used for estimating RIN various light sources in OCT questionable, cannot be applied uniformly different types sources. origin differs significantly, owing to physical nature photon generation. In this study, we characterize compare several including superluminescent diodes (SLDs), erbium-doped fiber amplifier,...

In order to offer an easier way study interactions between multiple cellular populations, we have developed a novel method precisely place cells in variety of nonoverlapping patterns using surface tension laterally open microchannels. Our design is fundamentally different from previous strategies such as compartmentalization, stamping, stenciling, or mechanical approaches. It relies on capillary action the propensity for liquid move more readily through narrow spaces result tension. Until...

Highlights • Delta check limits were established for frequently requested hormones An absolute delta percent is recommended to verify common adrenocorticotropic hormone should be set separately inpatients and outpatients This foundational data helps in laboratories

Abstract Whole-genome sequencing is the most comprehensive form of next-generation method. We aimed to assess additional diagnostic yield whole-genome in patients with clinically diagnosed Charcot–Marie–Tooth disease when compared whole-exome sequencing, which has not been reported literature. was performed on 72 families whose genetic cause revealed after and 17p12 duplication screening. Among included families, 14 (19.4%) acquired diagnoses that were compatible their phenotypes. The common...

The Cu-Cr system exhibits a miscibility gap in the liquid and has essentially no solid solubility. However, using low energy, <160 eV, Ar+ ion bombardment of growing film to promote ballistic collisional mixing, metastable single phase face-centered-cubic Cu-rich body-centered-cubic Cr-rich solutions have been grown on amorphous glass substrates at 75 °C. films were typically 1 μm thick with average grain sizes 90 110 nm, respectively, (111) preferred orientation. Annealing studies...

Stenotrophomonas maltophilia is a Gram-negative opportunistic pathogen that can cause serious infection. We aimed to analyze the prevalence and susceptibility rates trimethoprim/sulfamethoxazole of S. maltophilia. conducted retrospective study isolates from university hospital 2001 2020. Clinical information, numbers were analyzed by year. Susceptibility changes in respiratory non-respiratory samples compared. 1805 identified, which 81.4% (1469/1805) samples. There was male predominance 52%...

Abstract Objectives Few studies have reported on delta checks for tumour markers, even though these markers are often evaluated serially. Therefore, this study aimed to establish a practical check limit in different clinical settings five markers: alpha-fetoprotein, cancer antigen 19-9, 125, carcinoembryonic antigen, and prostate-specific antigen. Methods Pairs of patients’ results (current previous) between 2020 2021 were retrospectively collected from three university hospitals. The data...

Melatonin and cortisol are clinically important for diagnosing sleep mood disorders.We developed validated a liquid chromatography-tandem mass spectrometry (LC-MS/ MS) assay simultaneous measurement of salivary melatonin concentrations according to the Clinical Laboratory Standards Institute guidelines.Additionally, we compared LC-MS/MS with immunoassays, ELISA (Direct Salivary Elisa EK-DSM, Bühlmann Laboratories AG, Schönenbuch, Switzerland) electrochemiluminescence immunoassay (Cortisol...

This paper explores the integration of Lambert W function to a tolerance optimization problem with two unique features. First, Taguchi loss has been popular tool for quantifying quality incurred by customer. utilizes an empirical approach based on well-established regression analysis, which may be more appealing engineers and better capture customer's perception product performance. Second, trading off manufacturing rejection costs manufacturer customer, this shows how function, widely used...

Titin truncating variants (TTNtvs) are the most common genetic cause of dilated cardiomyopathy (DCM). Among four regions titin, A-band enrichment DCM-causing TTNtvs is widely accepted but underlying mechanism still unknown. Meanwhile, few reports have identified exon 327 as a highly mutated degree has not been quantitatively investigated. To find real hotspot TTNtvs, we aimed to reassess TTNtv in known titin and 327, separately. In addition, tried explain clustering terms nonsense-mediated...

The GENEDIA MTB/NTM Detection Kit (GENEDIA MTB/NTM; Green Cross Medical Science Corp., Chungbuk, Korea) is a multiplex real-time PCR assay used for differential identification of Mycobacterium tuberculosis complex (MTBC) and nontuberculous mycobacteria (NTM). While the importance recognized, there limited data on performance to date. A total 687 consecutive sputum specimens were cultured analyzed with MTB assays. Nineteen (2.8%) MTBC-positive, 69 (10.0%) NTM-positive based mycobacterial...

This study aimed to determine practical delta check limits (DCLs) for thyroid function tests (TFTs) detect sample misidentifications across various clinical settings. Between 2020 and 2022, 610,437 paired TFT results were collected from six university hospitals. The absolute DCL (absDCL) was determined using the 95th percentile each setting a random 60 % of total data. These absDCLs then tested within different settings remaining 40 data, alongside mix-up datasets result comparisons....

Cytomegalovirus (CMV) infection is a major cause of transplantation-related morbidity and mortality. This study assessed the utility QuantiFERON monitor (QFM; Qiagen) for prediction early CMV viral burden.

Various near‐eye displays have been commercialized over the past decade. They are approaching to be a form of ordinary eyeglasses. The majority researchers use planar waveguides as combiner, which do not distort image beam while being transferred along waveguide. However, combiners look like eyeglasses because they flat, curved. In this work an optical architecture with curved waveguide for near eye display is proposed. Two conditions transfer through defined. These satisfied using...

The Barricor tube (Becton Dickinson [BD], Sunnyvale, CA, USA) was recently developed to mechanically separate plasma by increasing the centrifugation rate. We compared with existing serum- and plasma-based tubes based on 35 biochemical analytes preanalytical turnaround time (TAT). Blood samples were collected from 30 healthy volunteers in a tube, serum separating (SST, Vacutainer SST II Tube 8.5 mL, #368972; BD), or (PST, PST 8.0 #367964; BD) random order. Next, 27 chemistry analytes, six...

Eye trackers play a crucial role in the development of future display systems, such as head-mounted displays and augmented reality glasses. However, ensuring robustness accuracy gaze estimation poses challenges, particularly with limited space available for transmitter receiver components within these devices. To address issues, we propose what believe is novel eye tracker design mounted on foldable temples, which not only supports accurate but also provides slim form-factor unobstructed...

Branchiootorenal (BOR) syndrome is a rare autosomal dominant inherited disease with prevalence of approximately 1 in 40,000 newborns. This characterized by hearing loss, preauricular pits, branchial fistulas or cysts, and renal dysplasia. We discovered case BOR premature 2-week-old female infant gestational age 32 weeks two days. She her family had major symptoms history BOR. was confirmed whole-genome sequencing structural variant calling, which revealed an EYA1 exon 5–6 deletion. The...