A5075529570- Nicotinic Acetylcholine Receptors Study
- Virology and Viral Diseases
- Viral Infections and Vectors
- Receptor Mechanisms and Signaling
- Mosquito-borne diseases and control
- SARS-CoV-2 detection and testing
- bioluminescence and chemiluminescence research
- Biosensors and Analytical Detection
- Pharmacological Effects and Assays
- Gene Regulatory Network Analysis
- Microbial Metabolic Engineering and Bioproduction
- Biochemical Analysis and Sensing Techniques
- Enzyme Catalysis and Immobilization
- Microfluidic and Capillary Electrophoresis Applications
- CRISPR and Genetic Engineering
- Plant biochemistry and biosynthesis
University of Copenhagen
2022-2025
Vidyasirimedhi Institute of Science and Technology
2020
Siriraj Hospital
2018
Mahidol University
2018
Kunming University of Science and Technology
2018
University of Arkansas for Medical Sciences
2018
Molecular Microbiology and Genomics Consultants (Germany)
2018
Abstract Eukaryotic cells use G-protein coupled receptors to sense diverse signals, ranging from chemical compounds light. Here, we exploit the remarkable sensing capacity of construct yeast-based biosensors for real-life applications. To establish proof-of-concept, focus on cannabinoids because their neuromodulatory and immunomodulatory activities. We a CB 2 receptor-based biosensor, optimize it achieve high sensitivity dynamic range, prove its effectiveness in three applications increasing...
Natural products are widely used as pharmaceuticals, flavors, fragrances, and cosmetic ingredients. Synthesizing evaluating analogs of natural can considerably expand their applications. However, the chemical synthesis is severely hampered by highly complex structures. This particularly evident in isoprenoids, largest class products. Here, we develop a yeast cell-based biocatalytic method that enables systematic biotechnological production different classes isoprenoids (including...
We present here the complete genome sequences of Zika virus strains isolated from aborted fetal tissue (brain and placenta) amniotic fluid a microcephaly patient in Thailand 2017. The genomes that were sequenced have an average length 10,807 nucleotides.
Abstract The decriminalization of cannabis and the growing interest in cannabinoids as therapeutics require efficient methods to discover novel compounds monitor cannabinoid levels human samples products. However, current are limited by structural diversity active compounds. Here, we construct a G-protein coupled receptor-based yeast whole-cell biosensor, optimize it achieve high sensitivity dynamic range, prove its effectiveness three real-life applications. First, screen library two...