A5081812509- Influenza Virus Research Studies
- Respiratory viral infections research
- Vector-borne infectious diseases
- Viral Infections and Vectors
- Vaccine Coverage and Hesitancy
- Vector-Borne Animal Diseases
- Rabies epidemiology and control
- Bartonella species infections research
- Mosquito-borne diseases and control
- Peripheral Neuropathies and Disorders
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Data-Driven Disease Surveillance
- Pediatric health and respiratory diseases
- Dermatological diseases and infestations
- Herpesvirus Infections and Treatments
- COVID-19 epidemiological studies
- Viral Infections and Immunology Research
- Erythrocyte Function and Pathophysiology
- Bacterial Infections and Vaccines
- Health Promotion and Cardiovascular Prevention
- Streptococcal Infections and Treatments
- Respiratory Support and Mechanisms
- Lipid metabolism and disorders
- Global Public Health Policies and Epidemiology
- Animal Disease Management and Epidemiology
University of Groningen
2023
University Medical Center Groningen
2023
National Institute for Public Health and the Environment
2013-2022
Utrecht University
2020
Radboud University Medical Center
2019
Jeroen Bosch Ziekenhuis
2019
University Medical Center Utrecht
2019
Radboud University Nijmegen
2019
Data on the relative contribution of influenza virus and other respiratory pathogens to infections in community-dwelling older adults (≥60 years) are needed.A prospective observational cohort study was performed Netherlands during 2 winters. Nasopharyngeal oropharyngeal swabs were collected influenza-like illness (ILI) episodes from controls. Viruses bacteria identified by multiplex ligation-dependent probe amplification assay conventional bacterial culture.The ILI incidence consecutive...
Influenza-like illness (ILI) can be caused by a range of respiratory viruses. The present study investigates the contribution influenza and other viruses, occurrence viral co-infections, persistence viruses after ILI onset in older adults. During season 2014–2015, 2366 generally healthy community-dwelling adults (≥60 years) were enrolled study. Viruses identified multiplex ligation–dependent probe-amplification assay naso- oropharyngeal swabs taken during acute phase, 2 8 weeks later....
Influenza vaccine effectiveness (IVE) varies over different influenza seasons and virus (sub)types/lineages. To assess the association between IVE circulating (sub)types/lineages, we estimated overall (sub)type specific in Netherlands. We conducted a test-negative case control study among subjects with influenza-like illness or acute respiratory tract infection consulting Sentinel Practices 11 (2003/2004 through 2013/2014) The adjusted was using generalized linear mixed modelling multiple...
Abstract Since the 2009 influenza pandemic, Netherlands has used a weekly death monitoring system to estimate deaths in excess of expectations. We present estimates during ongoing coronavirus disease (COVID-19) epidemic and 10 previous epidemics. Excess per averaged 4,000. The estimated 9,554 (41% excess) COVID-19 weeks 12–19 2020 appeared comparable 9,373 (18%) severe 2017–18. However, these occurred shorter time, had higher peak, were mitigated by nonpharmaceutical control measures....
During the 2009 influenza pandemic period, routine surveillance of influenza-like-illness (ILI) was conducted in The Netherlands by a network sentinel general practitioners (GPs). In addition during four other ILI/influenza systems existed. For preparedness, we evaluated performance system and others to assess which could be useful additions future. We also assessed whether five influenced media reports period. trends ILI consultation rates reported GPs from 20 April through 3 January 2010...
SUMMARY In this study, Coxiella burnetii seroprevalence was assessed for dairy and non-dairy sheep farm residents in The Netherlands 2009–2010. Risk factors seropositivity were identified residents. Participants completed farm-based individual questionnaires. addition, participants tested IgG IgM C. antibodies using immunofluorescent assay. by univariate, multivariate logistic regression, multilevel analyses. residents, 66·7% 51·3%, respectively. Significant risk cattle contact, high goat...
We aimed to examine the long-term correlation between influenza vaccination coverage and incidence of influenza-like illness (ILI) in total elderly populations European countries for which data was available on at least six consecutive seasons. graphically visualised ILI trends calculated Spearman rank coefficients. Additionally, we fitted a negative binomial regression model estimate change per percentage point coverage. found significant correlations population Netherlands (ρ = -0.60,...
Coxiella burnetii seroprevalence was assessed on Dutch dairy and non‐dairy sheep farms using ELISA. Risk factors for seropositivity were identified at farm level by univariate multivariate multilevel analyses. Based 953 5671 serum samples, seroprevalences 18.7 per cent 2.0 cent, respectively, 78.6 30.5 level. Significant risk location in the south of country, kept marginal grounds, one or several supply addresses ewes during 2007–2009 wearing boots and/or outfit professional visitors. On...
Whether areas affected by Q fever during a large outbreak (2008-2010) had higher rates of adverse pregnancy outcomes than not fever.Nationwide registry-based ecological study.Pregnant women in and the Netherlands, 2003-2004 2008-2010.Index group (N=58,737): pregnant 307 with more two notifications. Reference (N=310,635): 921 without As baseline, index reference years were also included to estimate effect 2008-2010, already existing differences before outbreak.Preterm delivery, small for...
Echocardiographic screening of acute Q-fever patients and antibiotic prophylaxis for with cardiac valvulopathy is considered an important approach to prevent chronic Q-fever-related endocarditis. During a large epidemic in the Netherlands, routine echocardiography was discontinued, raising controversy international literature. We followed cohort estimate risk developing Q-fever, we evaluated impact who were not yet known have valvulopathy.The study population consisted diagnosed 2007 2008....
Abstract From 2007 to 2010, the largest reported Q-fever epidemic occurred in Netherlands with 4026 notified laboratory-confirmed cases. During course of epidemic, health-seeking behaviour changed and awareness among health professionals increased. Changes laboratory workflows were implemented. The aim this study was analyse how these changes instigated adjustments notification criteria affected monitoring interpretation epidemic. We used articles on procedures related a description that...
Background From 2007 through 2010, a large epidemic of acute Q fever occurred in the Netherlands. Patients with cardiac valvulopathy are at high risk to develop chronic after an infection. This patient group was not routinely screened, so it is unknown whether all their infections were diagnosed. study aims investigate how many patients can be identified by screening and establish policy should changed. Methods In cross-sectional (2016–2017) hospital epicentre epidemic, blood sample taken...
Abstract In the aftermath of a large Q fever (QF) epidemic in Netherlands during 2007–2010, new chronic QF (CQF) patients continue to be detected. We developed health-economic decision model evaluate cost-effectiveness 1-time screening program for CQF 7 years after epidemic. The was parameterized with spatial data on notifications Netherlands, prevalence from targeted studies, and clinical national database. varied substantially among subpopulations geographic areas. Screening that focused...
Abstract We examined Coxiella burnetii seroconversion rates by measuring C. IgG among 2 cohorts of veterinary students. During follow-up 118 seronegative students, 23 students seroconverted. Although the clinical importance presence antibodies is unknown, should be informed about potential risks for Q fever.