Zhen Li

ORCID: 0000-0003-1433-6552
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About
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Research Areas
  • Ionic liquids properties and applications
  • Chemical Synthesis and Reactions
  • Genetic Mapping and Diversity in Plants and Animals
  • Carbon dioxide utilization in catalysis
  • Mesoporous Materials and Catalysis
  • Catalytic Processes in Materials Science
  • Oxidative Organic Chemistry Reactions
  • Multicomponent Synthesis of Heterocycles
  • Catalysis and Oxidation Reactions
  • Chromosomal and Genetic Variations
  • Cholinesterase and Neurodegenerative Diseases
  • Genetic and Kidney Cyst Diseases
  • N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
  • Pharmacological Effects and Assays
  • Sperm and Testicular Function
  • Plant Stress Responses and Tolerance
  • Advancements in Solid Oxide Fuel Cells
  • Electrochemical Analysis and Applications
  • Bacterial Infections and Vaccines
  • Phytochemistry and biological activity of medicinal plants
  • Phytochemistry and Biological Activities
  • Listeria monocytogenes in Food Safety
  • Covalent Organic Framework Applications
  • Genetics and Plant Breeding
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities

Guangxi University
2025

Wenzhou Medical University
2024

Zhejiang Lab
2024

Chonnam National University
2024

Chinese Academy of Sciences
2010-2023

Lanzhou Institute of Chemical Physics
2008-2023

Center for Excellence in Molecular Plant Sciences
2021-2023

National Center for Gene Research
2021-2023

Anhui Normal University
2021-2023

Shanghai Institute of Materia Medica
2019-2023

Abstract Exploitation of crop heterosis is crucial for increasing global agriculture production. However, the quantitative genomic analysis was lacking, and there currently no effective prediction tool to optimize cross-combinations. Here 2,839 rice hybrid cultivars 9,839 segregation individuals were resequenced phenotyped. Our findings demonstrated that indica – hybrid-improving breeding a process broadened genetic resources, pyramided breeding-favorable alleles through combinatorial...

10.1038/s41588-023-01495-8 article EN cc-by Nature Genetics 2023-09-07

Meiosis is the key step in gametogenesis. However, mechanism of mammalian meiosis remains poorly understood due to lack an vitro model. Here, we report that retinoic acid (RA) sufficient for inducing leptotene/zygotene spermatocytes from cultured mouse spermatogonial stem cells. Multiple genes regulated by RA were identified RNA sequencing. combination with pup Sertoli cell co-culture resulted a higher induction efficiency 28%. Comparisons transcriptomic profiles induced spermatogenic cells...

10.1016/j.stemcr.2016.05.013 article EN cc-by-nc-nd Stem Cell Reports 2016-06-25

Abstract The regulatory factor X (RFX) family of transcription factors is crucial for ciliogenesis throughout evolution. In mice, Rfx1-4 are highly expressed in the testis where flagellated sperm produced, but functions these spermatogenesis remain unknown. Here, we report production and characterization Rfx2 knockout mice. male mice were sterile due to arrest at an early round spermatid step. Rfx2- null spermatids detached from seminiferous tubules, forming large multinucleated giant cells...

10.1038/srep20435 article EN cc-by Scientific Reports 2016-02-08

Present design and application of perovskite oxide catalysts assume lattice oxygen redox (LOR) mechanisms that depend on activity without consideration the entire cycle. Herein, using in situ characterizations theoretical calculations, we uncover a hole-mediated LOR cycle p-type Sr-deficient SrFeO3-δ (SFO-Srv) perovskites CO oxidation reaction. Sr vacancies activate surface SFO-Srv promote formation highly covalent Fe(4-x)+-O(2-x)- sites. In electrical conductivity measurement demonstrates...

10.1002/anie.202424347 article EN Angewandte Chemie International Edition 2025-02-18

Bacillus spp. are considered pressure-resistant microorganisms, but the resistance mechanisms remain unknown. The spoVA 2mob operon is a mobile genetic element, and it can transfer to pathogenic or spoilage organisms by horizontal gene transfer. Results in this study indicate that multiple copies of mediate high-pressure endospores, might contribute identification source pathogens may contaminate food supply. droplet digital PCR (ddPCR) system well suited for analysis some human diseases due...

10.1128/aem.01596-19 article EN Applied and Environmental Microbiology 2019-08-02

Y–Si–O–N quaternary oxynitrides (Y 5 Si 3 O 12 N, Y 4 2 7 N , YS iO and ON 9 ) are recognized as important secondary grain‐boundary phases in silicon nitride believed to have impacts on the high‐temperature mechanical properties thermal conductivity of ceramic. In this work, equilibrium crystal structures, theoretical (second‐order elastic constants, polycrystalline bulk modulus shear Young's modulus, Vickers hardness) five calculated using first‐principle total energy calculations....

10.1111/jace.14238 article EN Journal of the American Ceramic Society 2016-04-05

Abstract magnified image Two new compounds, hastatusides A and B ( 1 2 , resp.), together with five known resveratrol, rumexoside, torachrysone‐8‐yl β ‐ D ‐glucopyranoside, rutin, nepodin, orientaloside were isolated from the roots of Rumex hastatus. Their structures determined by spectroscopic methods, including 1D‐ 2D‐NMR spectroscopy.

10.1002/hlca.200800395 article EN Helvetica Chimica Acta 2009-04-01

Salinity stress is a great threat to the growth and productivity of crops, development salt-tolerant crops necessity ensure food security. Although few genes with natural variations that confer salt tolerance at germination seedling stage in rice have been cloned, effective intragenic markers for these are awaited be developed, which hinder use genetic improvement rice. In this study, we first performed haplotype analysis five salt-tolerant-related using 38 accessions reference genome 4,726...

10.3389/fpls.2023.1259462 article EN cc-by Frontiers in Plant Science 2023-08-30

Diethylstilbestrol (DES), a synthetic nonsteroidal estrogen, has been prescribed for advanced breast cancer and prostate cancer. However, its poor compliance, reactive metabolite toxicity hydrophobicity-induced drug accumulation limited applications. In this study, we aimed to modulate dissolution rate reduce metabolites through cocrystallization. Cocrystals of DES with isonicotinamide (INA), picolinamide (PIN), nicotinamide (NIA), urea (UREA), sarcosine (SAR), flavone (FLA) were obtained....

10.1021/acs.cgd.8b01911 article EN Crystal Growth & Design 2019-01-23

With long-chained acidic ionic liquids as catalysts, a metal-free, efficient, and universal strategy was developed to synthesize series of benzoazole compounds through intermolecular cyclization 2-aminophenols/thiophenols/anilines with β-diketones. Compared traditional liquids, the certain surfactivity exhibited better catalytic activities perhaps for micellar action could be reused at least six times. A mechanism that involves condensation, nucleophilic addition, C–C bond cleavage proposed,...

10.1021/acssuschemeng.9b00497 article EN ACS Sustainable Chemistry & Engineering 2019-06-20

Abstract A highly efficient and eco‐friendly esterification was achieved by a series of novel dicationic acidic ionic liquids (DAILs) containing double SO 3 H cations. High yields the product esters were obtained using 2 mol% DAILs as catalysts DAIL I could be reused at least ten times without appreciable loss its efficicency.

10.1002/cjoc.201090334 article EN Chinese Journal of Chemistry 2010-10-01

The nucleophilic addition of thiocarbamate imidazolium ylide to aldehyde triggered sequential intramolecular N O migration thiocarbonyl amide group and reversible oxygen-sulfur rearrangement afford 2-imidazolium alkylcarbamothioate. ortho on phenyl strongly affects the balance O- S-rearrangement.

10.1039/c2ob26520f article EN Organic & Biomolecular Chemistry 2012-01-01

Silica-based mesoporous materials, such as SBA-15, are important supports in the field of catalysis due to their ordered pore channels.

10.1039/d3nj01680c article EN New Journal of Chemistry 2023-01-01
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