A5105513139- Antifungal resistance and susceptibility
- Pneumocystis jirovecii pneumonia detection and treatment
- Fungal Infections and Studies
- Tuberculosis Research and Epidemiology
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Mycobacterium research and diagnosis
- Transplantation: Methods and Outcomes
- Pneumonia and Respiratory Infections
- Infectious Diseases and Mycology
- Infectious Diseases and Tuberculosis
- HIV/AIDS drug development and treatment
- Asthma and respiratory diseases
- Inhalation and Respiratory Drug Delivery
- Pleural and Pulmonary Diseases
- Lung Cancer Diagnosis and Treatment
- Respiratory viral infections research
- Respiratory and Cough-Related Research
- Otolaryngology and Infectious Diseases
- Respiratory Support and Mechanisms
- Organ Transplantation Techniques and Outcomes
- Mosquito-borne diseases and control
- Healthcare Systems and Practices
- HIV Research and Treatment
- Renal Transplantation Outcomes and Treatments
- Nosocomial Infections in ICU
Assistance Publique – Hôpitaux de Paris
2014-2024
Hôpital Bichat-Claude-Bernard
2019-2024
Université Paris Cité
2020-2024
Université Claude Bernard Lyon 1
2021-2023
Délégation Paris 7
2022-2023
Inserm
2006-2023
Centre Hospitalier Universitaire de Poitiers
2008-2021
Physiopathologie et Epidémiologie des Maladies Respiratoires
2021
Hôpital Saint-Louis
2021
Laboratoire de Recherche Vasculaire Translationnelle
2021
Bedaquiline is a new antibiotic that was approved for the treatment of multidrug-resistant (MDR) tuberculosis. We aimed to evaluate short-term microbiological efficacy and tolerability profile bedaquiline.We performed retrospective cohort study among patients with MDR tuberculosis receiving bedaquiline compassionate use between January 2010 July 2013 evaluated at 6 months treatment.A total 35 were included in study. Nineteen (54%) had extensively drug-resistant (XDR) tuberculosis, 14 (40%)...
Chronic pulmonary aspergillosis (CPA) is an emerging disease in patients with common chronic diseases (CPDs). While its prevalence linked to tuberculosis (TB) endemic countries, epidemiological and prognostic data are lacking low TB incidence countries. The aim of this study was describe these features CPA hospitalised France between 2009 2018.We estimated the mortality using French nationwide administrative hospital database. We also assessed association CPD, thoracic interventions...
Pneumocystis jirovecii pneumonia (PCP) is emerging in HIV-negative patients, for whom the prognosis significantly worse than HIV-infected patients and risk factors are poorly characterized. We performed an observational, multi-centre, prospective study of 56 consecutive cases documented PCP found that: (1) main underlying conditions were haematological malignancies (43%), solid tumours (25%), inflammatory diseases (20%), organ transplantation (7%); (2) most (80%) had received prolonged...
The potential implication of interleukin (IL) 6, tumor necrosis factor α (TNF-α), and IL-10 in the protective effect low-dose lipopolysaccharide (LPS) administration against renal ischemia-reperfusion injury was evaluated a rat model. Eighteen male Sprague-Dawley rats were injected intravenously with either 0.5 mg/kg LPS (tolerant group) or saline (control 2 days before surgery. Ischemic induced by clamping left artery for 60 min on immediately after right-side nephrectomy. Reperfusion...
Chronic pulmonary aspergillosis (CPA) is a chronic fungal infection of the lung associated with high morbidity and mortality. The CPA Research network (CPAnet) registry established in 2018 an international multicenter collaboration aiming to improve knowledge patient care. This study’s aim was describe data collection process content CPAnet preliminary clinical data. In registry, are collected through web-based questionnaire. Data include phenotype, comorbidities, treatment, outcome,...
Mixed fungal infection and acquired echinocandin resistance of Candida spp. remain infrequent. In this study we have reported the case a patient hospitalized for tuberculosis who experienced multiple infections due to three common species (C. albicans, C. glabrata, tropicalis). Furthermore, consecutive isolates from blood cultures heart valve were found resistant azoles tropicalis) with either novel or previously described albicans) missense mutations in Fks gene.
Background Whereas first-line bronchial artery embolisation (BAE) is considered standard of care for the management severe haemoptysis, it unknown whether this approach warranted non-severe haemoptysis. Research question To assess efficacy on bleeding control and safety BAE in haemoptysis mild abundance. Study design methods This multicentre, randomised controlled open-label trial enrolled adult patients without major comorbid condition having (onset <72 hours, 100–200 mL estimated...