Guiru Zhang

ORCID: 0000-0003-1576-5287
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Research Areas
  • CO2 Reduction Techniques and Catalysts
  • Electrocatalysts for Energy Conversion
  • Acute Ischemic Stroke Management
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Catalytic Processes in Materials Science
  • Advanced battery technologies research
  • Carbon dioxide utilization in catalysis
  • Lipoproteins and Cardiovascular Health
  • Computational Fluid Dynamics and Aerodynamics
  • Catalysts for Methane Reforming
  • Cerebrovascular and Carotid Artery Diseases
  • Electrochemical Analysis and Applications
  • Atrial Fibrillation Management and Outcomes
  • Catalytic C–H Functionalization Methods
  • Oxidative Organic Chemistry Reactions
  • Radical Photochemical Reactions
  • Ionic liquids properties and applications
  • Venous Thromboembolism Diagnosis and Management
  • Advanced Photocatalysis Techniques
  • Advanced oxidation water treatment
  • Carbon Dioxide Capture Technologies
  • Gas Sensing Nanomaterials and Sensors
  • Fuel Cells and Related Materials
  • Dyeing and Modifying Textile Fibers
  • Intracerebral and Subarachnoid Hemorrhage Research

Shanghai Jiao Tong University
2021-2025

East China University of Science and Technology
2020-2022

Shandong Provincial Hospital
2018

Shandong University
2018

China Aerodynamics Research and Development Center
2013-2017

Coty (United States)
2017

Procter & Gamble (United States)
2014

Colorado State University
2003

Duke University
1997-2000

Vanderbilt University
2000

<h3>Objective:</h3> We aimed to investigate whether the efficacy and safety of clopidogrel plus aspirin vs alone were consistent between patients with without intracranial arterial stenosis (ICAS), in Clopidogrel High-Risk Patients Acute Non-disabling Cerebrovascular Events (CHANCE) trial. <h3>Methods:</h3> assessed interaction treatment effects 2 antiplatelet therapies among ICAS, identified by magnetic resonance angiography (MRA) CHANCE (ClinicalTrials.gov identifier NCT00979589)....

10.1212/wnl.0000000000001972 article EN Neurology 2015-08-29

Abstract The electrochemical carbon dioxide reduction reaction (CO 2 RR) is an attractive approach for mitigating CO emissions and generating value-added products. Consequently, discovery of promising RR catalysts has become a crucial task, machine learning (ML) been utilized to accelerate catalyst discovery. However, current ML approaches are limited exploring narrow chemical spaces provide only fragmentary catalytic activity, even though produces various chemicals. Here, by merging...

10.1038/s41467-023-43118-0 article EN cc-by Nature Communications 2023-11-11

Operando differential electrochemical mass spectroscopy investigation reveals the critical microenvironment of electrode surface topology, interfacial electric field and reactant concentration in determining CO 2 electrolysis performance.

10.1039/d1ee02966e article EN Energy & Environmental Science 2021-12-21

Electrochemical CO2 reduction is a typical surface-mediated reaction, with its reaction kinetics and product distributions largely dependent on the dynamic evolution of reactive species at cathode–catholyte interface resultant mass transport within hydrodynamic boundary layer in vicinity cathode. To resolve complex local environment branching pathways, we here present differential electrochemical spectroscopic (DEMS) approach for Cu electrodes to investigate transport, concentration...

10.1016/j.esci.2023.100143 article EN cc-by-nc-nd eScience 2023-05-19

<h3>Objective</h3> Evidence about whether neutrophil counts or ratio is associated with new stroke scant. The aim of this study to assess the association a in patients minor TIA. <h3>Methods</h3> We derived data from Clopidogrel High-Risk Patients With Acute Nondisabling Cerebrovascular Events trial. TIA were categorized into 4 groups according quartile ratio. primary outcome was (ischemic hemorrhagic), and secondary outcomes included composite vascular event (stroke, myocardial infarction,...

10.1212/wnl.0000000000005554 article EN Neurology 2018-04-20

Abstract The design for non‐Cu‐based catalysts with the function of producing C 2+ products requires systematic knowledge intrinsic connection between surface state as well catalytic activity and selectivity. In this work, photochemical in situ spectral characterization techniques combined first principle calculations (DFT) were applied to investigate relationships composition states, coordinated motifs, selectivity a titanium oxynitride catalyst. When catalyst mediates CO 2 photoreduction,...

10.1002/anie.202215574 article EN Angewandte Chemie International Edition 2022-12-08

Pt is a well-known benchmark catalyst in the acidic oxygen reduction reaction (ORR) that drives electrochemical O2-to-H2O conversion with maximum chemical energy-to-electricity efficiency. Once dispersing bulk into isolated single atoms, however, preferential ORR pathway remains long-standing controversy due to their complex local coordination environment and diverse site density over substrates. Herein, using set of carbon nanotube supported Pt–N–C single-atom catalysts, we demonstrate how...

10.1021/jacs.3c14186 article EN Journal of the American Chemical Society 2024-04-12

We aimed to determine the risk conferred by metabolic syndrome (METS) and diabetes mellitus (DM) recurrent stroke in patients with minor ischemic or transient attack from CHANCE (Clopidogrel High-risk Acute Non-disabling Cerebrovascular Events) trial.

10.1161/jaha.116.005446 article EN cc-by-nc-nd Journal of the American Heart Association 2017-06-02

<h3>Objective:</h3> To determine the association of lipoprotein-associated phospholipase A<sub>2</sub> (Lp-PLA<sub>2</sub>) measured in acute period and short-term risk recurrent vascular events patients with TIA or minor stroke. <h3>Methods:</h3> We Lp-PLA<sub>2</sub> activity (Lp-PLA<sub>2</sub>-A) a subset 3,201 participants enrolled CHANCE (Clopidogrel High-Risk Patients Acute Non-disabling Cerebrovascular Events) trial. Participants stroke were within 24 hours symptom onset randomized...

10.1212/wnl.0000000000001938 article EN Neurology 2015-08-27

Precise electrochemical synthesis of commodity chemicals and fuels from CO 2 building blocks provides a promising route to close the anthropogenic carbon cycle, in which renewable but intermittent electricity could be stored within greenhouse gas molecules. Here, we report state-of-the-art -to-HCOOH valorization performance over multiscale optimized Cu–Bi cathodic architecture, delivering formate Faradaic efficiency exceeding 95% an aqueous electrolyzer, C-basis HCOOH purity above 99.8%...

10.1073/pnas.2400898121 article EN cc-by-nc-nd Proceedings of the National Academy of Sciences 2024-07-09

To estimate the association of different patterns infarction and intracranial arterial stenosis (ICAS) with prognosis acute minor ischemic stroke TIA.We derived data from Clopidogrel in High-risk Patients Acute Nondisabling Cerebrovascular Events (CHANCE) trial. A total 1,089 patients 45 114 participating sites trial undergoing baseline MRI/angiography were included this subgroup analysis. Patterns ICAS recorded for each individual. The primary efficacy outcome was an at 90-day follow-up. We...

10.1212/wnl.0000000000003719 article EN Neurology 2017-02-16

To determine the relationship of glycated albumin (GA) and recurrence stroke in patients on either dual or single antiplatelet therapy.The Clopidogrel High-Risk Patients with Acute Nondisabling Cerebrovascular Events trial randomized minor ischemic TIA to therapy clopidogrel plus aspirin alone. A subgroup 3,044 consecutive baseline GA levels from 73 (64%) prespecified clinical sites was analyzed. were categorized into 2 groups based level 15.5%, cut point for development diabetes. The...

10.1212/wnl.0000000000001421 article EN Neurology 2015-03-05

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTEnantioselective Free Radical Allyl Transfers from Allylsilanes Promoted by Chiral Lewis AcidsNed A. Porter, Jason Hongliu Wu, Guiru Zhang, and Aimee D. ReedView Author Information Department of Chemistry, Duke University, Durham, North Carolina 27708Cite this: J. Org. Chem. 1997, 62, 20, 6702–6703Publication Date (Web):October 3, 1997Publication History Received2 July 1997Published online3 October inissue 1...

10.1021/jo971199+ article EN The Journal of Organic Chemistry 1997-10-01

Background and Purpose: Whether imaging parameters would independently predict stroke recurrence in low-risk minor ischemic (MIS) or transient attack (TIA) according to traditional score system (such as ABCD 2 score, which was termed on the basis of initials five factors: age, blood pressure, clinical features, duration, diabetes) remains unclear. We sought evaluate association between 1-year patients with TIA MIS different risk stratum stratified by score. Methods: included (National...

10.1161/strokeaha.120.032424 article EN Stroke 2021-05-05

Importance Previous studies revealed limited effectiveness of neuroprotective agents in treating acute ischemic stroke (AIS). Tongxinluo, developed from traditional Chinese medicines, has been recognized as a novel agent with anti-inflammatory properties that stabilize vulnerable plaques animal models and patients myocardial infarction. Objective To assess the efficacy safety Tongxinluo Design, Setting, Participants This multicenter, open-label, double-blind, randomized clinical trial...

10.1001/jamanetworkopen.2024.33463 article EN cc-by-nc-nd JAMA Network Open 2024-09-26
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