A5114778060- Photodynamic Therapy Research Studies
- Nanoplatforms for cancer theranostics
- Acne and Rosacea Treatments and Effects
- Immunotherapy and Immune Responses
- Nonmelanoma Skin Cancer Studies
- Skin Protection and Aging
- Infectious Diseases and Mycology
- Dermatologic Treatments and Research
- melanin and skin pigmentation
- Cutaneous lymphoproliferative disorders research
- RNA Interference and Gene Delivery
- Cervical Cancer and HPV Research
- Metal-Organic Frameworks: Synthesis and Applications
- Laser Applications in Dentistry and Medicine
- Bladder and Urothelial Cancer Treatments
- Pharmacological Effects of Natural Compounds
- Vascular Malformations and Hemangiomas
- Cancer Immunotherapy and Biomarkers
- Extracellular vesicles in disease
- Ginger and Zingiberaceae research
- Inflammation biomarkers and pathways
- Ginseng Biological Effects and Applications
- Advanced Biosensing Techniques and Applications
- Redox biology and oxidative stress
- Supramolecular Self-Assembly in Materials
Jiangxi University of Traditional Chinese Medicine
2021-2024
Clinical Trial Investigators
2024
Shanghai Skin Disease Hospital
2014-2023
Tongji University
2010-2023
State Key Laboratory of Supramolecular Structure and Materials
2022
Jilin University
2022
Shanghai Public Health Clinical Center
2020
Shihezi University
2010
Guangdong Polytechnic Normal University
2008
Xi'an University of Technology
2005
Phototherapy, particularly photothermal therapy (PTT) and photodynamic (PDT), has become a promising therapeutic technique for the treatment of skin cancers because its minial invasiveness, high efficacy, low side effects. Nevertheless, single modality therapy, either PTT or PDT, limited clinical effectiveness in treating cancers. Thus, combined applications PDT have been frequently reported; however, often require their respective photoagents excitation light sources, resulting challenges...
// Xiaojie Wang 1, * , Jie Ji Haiyan Zhang 1 Zhixia Fan Linglin Lei Shi Feifan Zhou 2 Wei R. Chen 2, Hongwei 3 Xiuli Shanghai Skin Disease Hospital, 200443, China Biophotonics Research Laboratory, Center for Interdisciplinary Biomedical Education and Research, University of Central Oklahoma, Edmond, OK 73034, USA Huadong Fudan University, 200040, These authors have contributed equally to this work Correspondence to: Wang, e-mail: wangxiuli20150315@163.com hongweiwang2005@aliyun.com Keywords:...
// Jie Ji 1, * , Zhixia Fan Feifan Zhou 2 Xiaojie Wang 1 Lei Shi Haiyan Zhang Peiru Degang Yang Linglin Wei R. Chen 2, Xiuli Department of Photomedicine, Shanghai Skin Disease Hospital, 200443, China Biophotonics Research Laboratory, Center for Interdisciplinary Biomedical Education and Research, University Central Oklahoma, Edmond, OK 73034, USA These authors have contributed equally to this work Correspondence to: Wang, e-mail: xlwang2001@aliyun.com Chen, wchen@uco.edu Keywords: dendritic...
Rosacea is a common chronic facial inflammatory disease that affects millions of people worldwide. Due to the unclear etiology rosacea, effective treatments are limited. Celastrol, plant-derived triterpene, has been reported alleviate inflammation in various diseases. However, whether celastrol exerts protective effects rosacea remains be elucidated. In this study, weighted gene co-expression network analyses (WGCNA) were performed. Hub modules closely related clinical characteristics...
In the intensive care unit (ICU), patients often experience restricted mobility due to their critical condition, potentially leading negative effects on both muscle strength and immune function. Previous research has highlighted beneficial of early mobilization among patients, regardless mechanical ventilation status. Hence, bed cycling serves as a potential facilitator for is considered feasible intervention critically ill within ICU. To mitigate this concern, we propose randomized...
5‐Aminolevulinic acid photodynamic therapy (ALA‐PDT) is known to be effective in the treatment of photoaged skin. However, molecular mechanisms still remain elusive. Protoporphyrin IX (PpIX) fluorescence primarily located epidermis while ALA‐PDT affects dermal collagen, presumably by an indirect mechanism. This study aimed investigate communication low‐dose occurring between epidermal keratinocytes and fibroblasts. Western blotting enzyme‐linked immunosorbent assays were performed evaluate...
Importance Previous studies revealed limited effectiveness of neuroprotective agents in treating acute ischemic stroke (AIS). Tongxinluo, developed from traditional Chinese medicines, has been recognized as a novel agent with anti-inflammatory properties that stabilize vulnerable plaques animal models and patients myocardial infarction. Objective To assess the efficacy safety Tongxinluo Design, Setting, Participants This multicenter, open-label, double-blind, randomized clinical trial...
Background: Laser immunotherapy is a new anti-cancer therapy combining photothermal and immunostimulation. It can eliminate the tumours by damaging tumour cells directly promoting release of damage-associated molecular patterns (DAMPs) to enhance immunogenicity. The aim this study was investigate thermal effects laser evaluate effectiveness safety for cutaneous squamous cell carcinoma (cSCC).Methods: viability DAMPs productions heat-treated cSCC A431 in different temperatures were...
Abstract 5‐Aminolevulinic acid‐photodynamic therapy (ALA‐PDT) is a relatively novel therapeutic technique that used widely in dermatology. ALA can penetrate the stratum corneum into skin and convert to protoporphyrin IX (PpIX) exert photodynamic response. Due its advantages of allowing repetitive application multiple lesions, non‐trauma excellent cosmetic results, ALA‐PDT for treatment actinic keratosis, moderate severe acne, condyloma acuminate other diseases showing strong or promising...
Targeted immunotherapy using dendritic cell vaccine has been employed for the treatment of solid tumors. Topical 5-aminolevulinic acid-mediated photodynamic therapy, an established approach topical cancers, can induce effective antitumor immune response. We have previously shown that therapy-induced tumor lysates could considerably enhance antigen-presenting capacity ex vivo-generated cells. The current study further demonstrates therapy responses against cancers. Dendritic cells pulsed by...
Abstract Background Laser therapies have brought dawn to refractory skin diseases, but also were accompanied by postlaser inflammation and barrier dysfunction. To recover function quickly, the research development of active ingredients including β‐glucan for repair attracted much attention. Aims evaluate efficacy tolerance care regimens containing (Dermdoc®;Songyang Biotech) in repairing dysfunction after fractional laser therapy. Methods A total 20 patients with facial atrophic acne scars...