A5065278495- Health, Environment, Cognitive Aging
- Attention Deficit Hyperactivity Disorder
- Genetics and Neurodevelopmental Disorders
- Birth, Development, and Health
- Child and Adolescent Psychosocial and Emotional Development
- Neonatal Respiratory Health Research
- Autism Spectrum Disorder Research
- Neuroendocrine regulation and behavior
- Resilience and Mental Health
- Cognitive Abilities and Testing
- Linguistic, Cultural, and Literary Studies
- Cardiovascular Issues in Pregnancy
- Congenital heart defects research
- Child Nutrition and Feeding Issues
- Epigenetics and DNA Methylation
- Genomic variations and chromosomal abnormalities
- Cardiac Valve Diseases and Treatments
- Genetic Associations and Epidemiology
- Child Abuse and Trauma
- Early Childhood Education and Development
- Health and Well-being Studies
- Congenital Heart Disease Studies
- Reproductive Health and Technologies
- Homicide, Infanticide, and Child Abuse
- Childhood Cancer Survivors' Quality of Life
University of Oslo
2022-2024
University of Bergen
2018-2021
Haukeland University Hospital
2018
Recurrent copy number variations (CNVs) are common causes of neurodevelopmental disorders (NDDs) and associated with a range psychiatric traits. These CNVs occur at defined genomic regions that particularly prone to recurrent deletions duplications often exhibit variable expressivity incomplete penetrance. Robust estimates the population prevalence inheritance pattern (NDD CNVs) lacking. Here we perform array-based CNV calling in 12,252 mother-father-child trios from Norwegian Mother,...
Research on mental health has traditionally separated the study of illbeing—disorder and problems—and wellbeing—life satisfaction positive affect. While previous reviews studies primarily employing self-report scales indicate that illbeing wellbeing are distinct yet interconnected constructs, a deeper examination their relationship is lacking. This perspective article from PROMENTA Center offers review synthesis findings joint nature across multiple levels analysis. Adopting an...
BACKGROUNDEpidemiological studies suggest that the maternal diet quality during pregnancy may influence risk of neurodevelopmental disorders in offspring. Here we investigated associations between intake dietary fiber and ADHD symptoms early childhood.METHODSWe used longitudinal data up to 21,852 mother-father-child trios (49.2% females) from Norwegian Mother, Father, Child Cohort Study. The relationships offspring at ages three, five, eight years were examined using: a) multivariate...
Do expectant parents experience increased anxiety and depression during pregnancies conceived through ART compared to spontaneous conception?Among all in the sample, those who reported overall lower levels of pregnancy spontaneously, while subsample both conception, mothers experienced early following conception.Previous research on parents' psychosocial adjustment response has found mixed results, with some studies suggesting is associated depression, other improved mental health or no...
Abstract Introduction Intelligence is a core construct of individual differences in cognitive abilities and strong predictor important life outcomes. Within recent years, rates cesarean section have substantially increased globally, though little known about its effect on neurodevelopmental trajectories. Thus, we aimed to investigate the influence delivery by genetics intelligence children. Methods Participants were recruited through Avon Longitudinal Study Parents Children (ALSPAC). was...
The goal of this prospective longitudinal study was to explore whether co-occurrent internalizing difficulties and aggression in early childhood convey increased risk for later mental health problems middle childhood. Participants were mothers from the Norwegian Mother, Father Child Cohort Study (MoBa), who provided assessments child at ages 3 years ( n = 54,644; 26,750 girls) 5 38,177; 18,794 girls), as measures depressive, anxiety, conduct-related, oppositional defiant (OD) symptoms age 8...
Autism spectrum disorder (ASD), attention-deficit/hyperactivity (ADHD), and schizophrenia (SCZ) are highly heritable linked to disruptions in foetal (neuro)development. While epigenetic processes considered an important underlying pathway between genetic susceptibility neurodevelopmental conditions, it is unclear (i) whether these conditions associated with patterns, specifically DNA methylation (DNAm), already at birth; (ii) what extent DNAm patterns unique or shared across (iii) neonatal...
Psychological stress during pregnancy is known to have a range of long-lasting negative consequences on the development and health offspring. Here, we tested whether measure prenatal early-life was associated with biomarker physiological at birth, namely epigenetic gestational age, using foetal cord-blood DNA-methylation data. Longitudinal cohorts from Netherlands (Generation R Study [Generation R], n = 1,396), UK (British Avon Parents Children [ALSPAC], 642), Norway (Mother, Father Child...
Research on mental health has traditionally separated the study of illbeing—disorder and problems—and wellbeing—life satisfaction positive affect. While previous reviews studies primarily employing self-report scales indicate that illbeing wellbeing are distinct yet interconnected constructs, a deeper examination their relationship is lacking. This perspective article from PROMENTA Center offers review synthesis findings joint nature across multiple levels analysis. Adopting an...
Abstract Body Genome-wide Association Studies in Psychiatry - Current Perspectives Last decade was exciting time for human genetic studies. association studies (GWASs), used to examine the of genotyped variants across entire genome and common complex phenotype(s), have led many findings. Currently, GWAS Catalogue has collected 4,809 publications 227,262 associated variants. In recent years, psychiatric genetics enjoyed some success discoveries This mostly happened because researchers were...
Understanding whether co-occurrent internalizing difficulties (ID) and aggression in early childhood convey increased risk for later mental health problems is important theoretical clinical purposes. To investigate this, mothers from the Norwegian Mother, Father Child Cohort Study (MoBa) reported on child ID at ages 3 (n=54,644; 26,750 girls) 5 (n=38,177; 18,794 girls); depressive, anxiety, conduct-related, opposition-defiant symptoms age 8. Using aggression, four profiles emerged:...