- Peripheral Artery Disease Management
- Diagnosis and Treatment of Venous Diseases
- Palliative Care and End-of-Life Issues
- Venous Thromboembolism Diagnosis and Management
- Childhood Cancer Survivors' Quality of Life
- Ethics and Legal Issues in Pediatric Healthcare
- Family and Patient Care in Intensive Care Units
- Vascular Procedures and Complications
- Muscle and Compartmental Disorders
- Long-Term Effects of COVID-19
- Cruise Tourism Development and Management
- Inflammasome and immune disorders
- Schizophrenia research and treatment
- Cardiovascular Health and Disease Prevention
- COVID-19 Clinical Research Studies
- Healthcare Decision-Making and Restraints
- Health Systems, Economic Evaluations, Quality of Life
- Medical Coding and Health Information
- Emergency and Acute Care Studies
- Cerebrovascular and Carotid Artery Diseases
- Protease and Inhibitor Mechanisms
- Cancer Immunotherapy and Biomarkers
- Poisoning and overdose treatments
- Healthcare cost, quality, practices
- Central Venous Catheters and Hemodialysis
University of Oslo
2013-2022
Oslo University Hospital
2019-2022
Otivio (Norway)
2019-2021
Lovisenberg Diakonale Høgskole
2020
Inland Hospital
2017
This study compared the Charlson comorbidity index (CCI) information derived from chart review and administrative systems to assess completeness agreement between scores, evaluate capacity predict 30-day 1-year mortality in intensive care unit (ICU) patients, compare predictive with that of Simplified Acute Physiology Score (SAPS) II model.Using data 959 patients admitted a general ICU Norwegian university hospital 2007 2009, we CCI score systems. Agreement was assessed using % agreement,...
A high proportion of COVID-19 patients have cardiac involvement, even those without known disease. Downregulation angiotensin converting enzyme 2 (ACE2), a receptor for SARS-CoV-2 and the renin-angiotensin system, as well inflammatory mechanisms been suggested to play role. ACE2 is abundant in gut associated with microbiota composition. We hypothesized that leakage microbial products, subsequent inflammasome activation could contribute involvement patients.Plasma levels marker (LPS-binding...
Background To withhold and withdraw treatment are important difficult decisions made in the intensive care unit ( ICU ). The aim of this study was to investigate incidence withholding or withdrawing treatment, characteristics patients, how these decision processes were handled documented a general from 2007 2009 university hospital N orway. Methods Patient outcomes prospectively registered. We retrospectively reviewed medical records for information on limitations treatment. Results In...
Purpose Few previous studies have investigated associations between clinical variables available after 24 hours in the intensive care unit (ICU), including Charlson Comorbidity Index (CCI), and decisions to restrict life-sustaining treatment. The aim of this study was identify factors associated with treatment restriction explore if CCI contributes explaining ICU at a university hospital Norway from 2007 2009. Methods Patients' Simplified Acute Physiology Score II (SAPS II), age, sex, type...
We investigated the effects of lower extremity intermittent negative pressure (INP) treatment for 1 hour two times daily 12 weeks on walking distance patients with claudication (IC).Patients IC were randomized to -40 mm Hg INP (treatment group) or -10 (sham control group). Pain-free (PWD) and maximal (MWD) a treadmill, resting postexercise ankle-brachial index, postischemic blood flow (plethysmography), quality life (EQ-5D-5L Vascuqol-6) measured at baseline after treatment.A total 72...
Intermittent negative pressure (INP) applied to the lower leg induces acute increase in arterial and skin blood flow. The aim of this study was identify optimal level INP flow patients with extremity peripheral artery disease (PAD). We investigated effects different levels 16 subjects (7 women 9 men, mean (SD) age 71(8) years) diagnosed PAD. During application a chamber sealed below knee, continuously recorded dorsalis pedis or tibialis posterior (ultrasound Doppler), at pulp first toe...
Background Critical limb ischaemia is a severe stage of lower peripheral artery disease which can lead to tissue loss, gangrene, amputation and death. FlowOx™ therapy novel negative-pressure chamber system intended for home use increase blood flow, reduce pain improve wound healing patients with critical ischaemia. Methods A Markov model was constructed assess the relative cost-effectiveness compared standard care in intermittent claudication or The used data from two European trials...
BackgroundTreatment with lower extremity intermittent negative pressure (INP) of -40 mm Hg for one hour twice daily 12 weeks, increases walking capacity in patients claudication (IC). However, the effects INP treatment beyond weeks have not been elucidated. The aim present study was to investigate clinical after 24 IC.MethodsThis a follow-up randomized sham-controlled trial, where active group were offered continue additional (24 total). Treatment applied chamber sealed around leg, and...
The aim of this study was to investigate the effects lower extremity intermittent negative pressure (INP) treatment for 1 hour twice daily 12 weeks, on circulating vascular biomarkers in patients with claudication. Patients were randomized –40 mmHg INP (treatment group), or –10 (sham control group). Venous blood samples collected at baseline and after concentrations adhesion molecule-1 (VCAM-1), intracellular (ICAM-1), E-selectin, P-selectin, von Willebrand factor (vWF), l-arginine,...