Filipe Leal Portilho

ORCID: 0000-0003-2016-1947
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About
Contact & Profiles
Research Areas
  • Nanoparticle-Based Drug Delivery
  • Nanoparticles: synthesis and applications
  • Nanoplatforms for cancer theranostics
  • Graphene research and applications
  • Cancer Cells and Metastasis
  • Cancer Genomics and Diagnostics
  • Graphite, nuclear technology, radiation studies
  • Mass Spectrometry Techniques and Applications
  • Innovation Policy and R&D
  • RNA Interference and Gene Delivery
  • Breast Cancer Treatment Studies
  • Systemic Lupus Erythematosus Research
  • Advanced biosensing and bioanalysis techniques
  • Psoriasis: Treatment and Pathogenesis
  • Drug Transport and Resistance Mechanisms
  • Pancreatic and Hepatic Oncology Research
  • Tuberculosis Research and Epidemiology
  • BRCA gene mutations in cancer
  • Malaria Research and Control
  • Graphene and Nanomaterials Applications
  • Rheumatoid Arthritis Research and Therapies
  • Neuroblastoma Research and Treatments
  • Lipid Membrane Structure and Behavior
  • Parasites and Host Interactions
  • Adipokines, Inflammation, and Metabolic Diseases

Nuclear Engineering Institute
2017-2023

National Nuclear Energy Commission
2022

Universidade Estadual da Zona Oeste
2018

Cancer is responsible for more than 12% of all causes death in the world, with an annual rate 7 million people. In this scenario melanoma one most aggressive ones serious limitation early detection and therapy. direction we developed, characterized tested vivo a new drug delivery system based on magnetic core-mesoporous silica nanoparticle that has been doped dacarbazine labelled technetium 99 m to be used as nano-imaging agent (nanoradiopharmaceutical) differential diagnosis by single...

10.1080/21691401.2018.1443941 article EN Artificial Cells Nanomedicine and Biotechnology 2018-02-27

Breast cancer is women's most common type of cancer, with a global rate over 522,000 deaths per year. One the main problems related to breast relies in early detection, as specialized treatment. In this direction was developed, characterized and tested vivo smart delivery system, based on radiolabelled magnetic core mesoporous silica doped trastuzumab intralesional nanodrug for imaging possible therapy. The results showed that nanoparticles had size 58.9 ± 8.1 nm, specific surface area 872...

10.1080/21691401.2018.1508030 article EN Artificial Cells Nanomedicine and Biotechnology 2018-11-12

The production of radiopharmaceuticals, especially the PET ones, is a complex combination economic and social factors. Despite aspects, that are essential, issue must be considered play an important parameter for implementation maintenance producer centers around world, with especial regards countries which face crisis and/or belongs to aegis under development countries.In order evaluate this scenario carried out study, comparing well-established center in Brazil new on Belarus.The results...

10.2174/1874471011666171211164111 article EN Current Radiopharmaceuticals 2017-12-12

This study explores the application of graphene quantum dots (GQDs) as innovative nanomaterials for efficient removal nuclear materials from metal and plastic surfaces, especially in contexts involving terrorist threats, such “dirty bombs” radiological dispersal devices (RDDs). These use conventional explosives combined with radioactive to contaminate large areas, posing significant risks health environment. investigation addresses growing global concern about threat...

10.36922/eer.3403 article EN 2024-10-14

Breast cancer is the main leading type of for women around world and responsible 522,000 deaths per year worldwide. In order to reduce this number, clinicians researchers are always looking new strategies protocols. However, treatment breast challenging requires as much information possible. To end, we conducted a review all protocols used in last 35 years with objective help choose best possible available their region. Many international references, that reason have been many countries like...

10.6000/1927-7229.2017.06.02.2 article EN Journal of Analytical Oncology 2017-05-02
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