- Breastfeeding Practices and Influences
- Infant Nutrition and Health
- Evolutionary Psychology and Human Behavior
- Gut microbiota and health
- COVID-19 Impact on Reproduction
- Child Nutrition and Water Access
- Demographic Trends and Gender Preferences
- Neonatal Respiratory Health Research
- Neuroendocrine regulation and behavior
- Rangeland Management and Livestock Ecology
- Human-Animal Interaction Studies
- Child and Adolescent Psychosocial and Emotional Development
- Indigenous Studies and Ecology
- Infant Health and Development
- Prenatal Substance Exposure Effects
- Child Nutrition and Feeding Issues
- COVID-19 and Mental Health
- Cannabis and Cannabinoid Research
- Viral gastroenteritis research and epidemiology
- Stress Responses and Cortisol
- Digestive system and related health
- Attachment and Relationship Dynamics
- Milk Quality and Mastitis in Dairy Cows
- Probiotics and Fermented Foods
- Epigenetics and DNA Methylation
Washington State University
2015-2024
Background: Human milk is a complex fluid comprised of myriad substances, with one the most abundant substances being group carbohydrates referred to as human oligosaccharides (HMOs). There has been some evidence that HMO profiles differ in populations, but few studies have rigorously explored this variability. Objectives: We tested hypothesis diverse populations healthy women. Next, we examined relations between and maternal anthropometric reproductive indexes indirectly whether differences...
Whether mother-to-infant SARS-CoV-2 transmission can occur during breastfeeding and, if so, whether the benefits of outweigh this risk maternal COVID-19 illness remain important questions. Using RT-qPCR, we did not detect RNA in any milk sample (
Background Microbial communities in human milk and those feces from breastfed infants vary within across populations. However, few researchers have conducted cross-cultural comparisons between populations, little is known about whether certain "core" taxa occur normally or populations variation microbiome related to infant fecal microbiome. The purpose of this study was describe microbiomes produced by relatively healthy women living at diverse international sites compare these the their...
Previous research among foragers and theory suggests that nonmaternal caregivers offer essential assistance, which supports female reproduction the costs associated with lengthy child development. Mothers' face trade-offs in energy allocation between work childcare, particularly when mothers have an infant. These likely crucial impacts on pace of health. Caregivers can help childcare or they reduce a mother's nonchildcare workload. If assist by substituting then maternal expenditure (EE)...
Human milk provides a very wide range of nutrients and bioactive components, including immune factors, human oligosaccharides, commensal microbiota. These factors are essential for interconnected processes immunity programming the development normal infant gastrointestinal microbiome. Newborn protection mostly relies on maternal provided through milk. However, studies dealing with an in-depth profiling different compounds present in assessment their natural variation healthy women from...
Abstract Background It is not known whether SARS-CoV-2 can be transmitted from mother to infant during breastfeeding, and if so the benefits of breastfeeding outweigh this risk. This study was designed evaluate 1) RNA detected in milk on breast infected women, 2) concentrations milk-borne anti-SARS-CoV-2 antibodies, 3) capacity neutralize infectivity. Methods We collected 37 samples 70 swabs (before after washing) 18 women recently diagnosed with COVID-19. Samples were analyzed for using...
The novel coronavirus SARS-CoV-2 has emerged as one of the most compelling public health challenges our time. To address myriad issues generated by this pandemic, an interdisciplinary breadth research, clinical, and communities have rapidly engaged to find answers solutions. One area active inquiry is understanding mode(s) transmission. While respiratory droplets are a known mechanism transmission, other mechanisms possible. Of particular importance global possibility vertical transmission...
Previously published data from our group and others demonstrate that human milk oligosaccharide (HMOs), as well infant fecal microbial profiles, vary by geography. However, little is known about the geographical variation of other milk-borne factors, such lactose protein, associations among these factors community structures in feces. Here, we characterized contrasted concentrations lactose, HMOs, examined their with microbiomes samples collected 11 geographically diverse sites. Although...
We present the first available data on human milk microbiome (HMM) from small-scale societies (hunter-gatherers and horticulturalists in Central African Republic [CAR]) explore relationships among subsistence type seasonality HMM diversity composition. Additionally, as humans are cooperative breeders and, throughout our evolutionary history today, we rear offspring within social networks, examine associations between environment HMM. Childrearing breastfeeding exist a biosocial nexus, which...
Human milk oligosaccharides (HMO), the third most abundant component of human milk, are thought to be important contributors infant health. Studies have provided evidence that geography, stage lactation, and Lewis secretor blood groups associated with HMO profile. However, little is known about how variation across genome may influence composition among women in various populations. In this study, we performed genome-wide association analyses 395 from 8 countries identify genetic regions 19...
Our primary objective was to understand breastfeeding individuals' decisions use cannabis. Specifically, we investigated reasons for cannabis use, experiences with healthcare providers regarding and potential concerns about use.
ABSTRACT Research suggests that nonmaternal caregivers (allomothers) offer essential assistance through caregiving and provisioning, helping to support lengthy child development. Here, we examine the role of allomothers broader social sharing network on Aka forager children's anthropometrics. We hypothesize investors strategically target their when it is most needed will have greatest effect. evaluate nutritional status using WHO standards [weight‐for‐age (WAZ), height‐for‐age (HAZ),...
Limited data are available regarding the balance of risks and benefits from human milk and/or breastfeeding during following maternal infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Abstract Objectives Establishment and development of the infant gastrointestinal microbiome (GIM) varies cross‐culturally is thought to be influenced by factors such as gestational age, birth mode, diet, antibiotic exposure. However, there little data how composition infants' households may play a role, particularly from cross‐cultural perspective. Here, we examined relationships between fecal (IFM) diversity/composition household size, number siblings, other members. Materials methods We...
Abstract Objectives Evolution of human maternal investment strategies is hypothesized to be tied biological constraints and environmental cues. It likely, however, that the socioecological context in which mothers' decisions are made equally important. Yet, a lack studies examining from cross‐cultural, holistic approach has hindered our ability investigate evolution strategies. Here, we take systems‐level study how life history characteristics, environments, socioecology influence their...
ABSTRACT Objectives This study aimed to evaluate whether postpartum maternal stress is associated with infant gastrointestinal microbiome composition and diversity, this relationship may be mediated by caregiving breastfeeding behaviors human milk (HMM) composition. Methods Infant fecal samples were collected from 51 exclusively mother‐infant dyads in the Pacific Northwest between 1 6 months postpartum. sequencing read counts > 773 ( n = 48) 200 46) analyzed for bacterial alpha diversity...
Background There is a paucity of data on the presence severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in feces lactating women with disease 2019 (COVID-19) and their breastfed infants as well associations between fecal shedding symptomatology. Objective We examined whether to what extent SARS-CoV-2 detectable following maternal COVID-19 diagnosis. Methods This was longitudinal study carried out from April 2020 December 2021 involving 57 breastfeeding maternal-infant dyads: 33...
As cannabis use increases among reproductive-aged women, there is a growing need to better understand the presence of cannabinoids in milk produced by women using cannabis. It unclear how concentrations such as delta-9-tetrahydrocannabinol (Δ