A5081883708- Tryptophan and brain disorders
- Neuroscience and Neuropharmacology Research
- Receptor Mechanisms and Signaling
- Stress Responses and Cortisol
- Amino Acid Enzymes and Metabolism
- Neuroendocrine regulation and behavior
- Neurotransmitter Receptor Influence on Behavior
- Pharmaceutical Practices and Patient Outcomes
- Schizophrenia research and treatment
- Diet and metabolism studies
- Cancer Immunotherapy and Biomarkers
- Pharmacological Receptor Mechanisms and Effects
- Mast cells and histamine
- COVID-19 and Mental Health
- Biochemical Analysis and Sensing Techniques
- Pancreatic and Hepatic Oncology Research
- Asthma and respiratory diseases
- Olfactory and Sensory Function Studies
- Pharmacy and Medical Practices
- Adipose Tissue and Metabolism
- Anesthesia and Neurotoxicity Research
- Nausea and vomiting management
- Neuroinflammation and Neurodegeneration Mechanisms
- Treatment of Major Depression
- Neuropeptides and Animal Physiology
Nagoya University Hospital
2016-2025
Meijo University
2010-2022
Kinjo Gakuin University
2014
Extensive studies have been performed on the role of monoaminergic neuronal systems in rodents exposed to social defeat stress as adults. In present study, we investigated impairment behaviors induced by exposure juveniles.Juvenile, male C57BL/6J mice were for 10 consecutive days. From 1 day after last exposure, desipramine, sertraline, and aripiprazole administered 15 Social assessed at days exposure. Monoamine turnover was determined specific regions brain stress.Stress juveniles...
Objective We attempted to investigate whether dehydroepiandrosterone sulfate (DHEA‐S) levels are associated with remission of major depressive disorder by assessing scores on the 17‐Item Structured Interview Guide for Hamilton Depression before and after antidepressant treatment. Methods Plasma DHEA‐S in 24 patients diagnosed basis Diagnostic Statistical Manual Mental Disorders, fourth edition (text revision) treatment, healthy, gender‐matched, age‐matched controls were measured using a...
Abstract Background Antipsychotics are essential in the acute treatment of and maintenance therapy for schizophrenia, but medication adherence long-term continuity needed to maximize their effectiveness. Each antipsychotic has various side effects, which may affect adherence. Some patients with schizophrenia reluctant take asenapine because its unique oral-related such as bitter taste caused by sublingual administration. Our previous basic research found that D-sorbitol lowered bitterness...
Continual long-term use of inhaled corticosteroids is crucial for asthma treatment, and poor medication adherence can lead to the exacerbation asthma. However, difficult secure in patients with chronic diseases such as To identify factors influencing asthma, we analyzed relationship between different evaluated during counseling adherence. We found a significant positive correlation inhalation technique, insight, illness insight. No was observed state control. These results suggest that who...
Over recent years, use of self-medication by patients to help prevent and treat their own medical conditions has become increasingly widespread. However, despite provision warnings the taking precautions, health hazards due medication have occurred continue occur. In order ward off such incidents, it is necessary for both children adults be educated about appropriate drug use. And, desirable that pharmacy students participate in this medicinal education as a means affirming what they learned...
Chemotherapy‑induced nausea and vomiting (CINV) can cause anorexia, weight loss deterioration of patient quality life. It is one the most unpleasant adverse effects chemotherapy treatment regimens. For optimal gastrointestinal symptoms during urothelial carcinoma chemotherapy, present study investigated association between therapeutic gemcitabine plus platinum [cisplatin (GC) or carboplatin (GCa)] therapies. The incidence frequency nausea/vomiting with GC split therapy (gemcitabine, 1,000...
Abstract Background Asenapine has unique orally-related side effects, such as a bitter taste induced by sublingual administration, which often results in discontinuation of the medication. While FDA approved black-cherry-flavored asenapine, several countries have prescribed only unflavored versions. Specifically, Asians commonly report experiencing bitterness asenapine because they are more sensitive to tastes than other ethnic groups. In this study, with aim improving adherence reducing we...
We held classes and practice sessions on medicines for pupils parents at elementary schools with the aim of promoting appropriate drug use. Pharmacy students participated in this project as volunteers where they taught learned improved their communication skills an early stage professional development. To evaluate whether medicine-related knowledge after attending these sessions, we conducted questionnaires (pre- post-questionnaires) before sessions. Positive answers post-questionnaire were...
In a cisplatin (a highly emetogenic anti-cancer agent)-containing regimen, administrations of fluid replacement and/ or diuretic drugs are performed to relieve nephrotoxicity.Such treatments will alter the body＇s water balance, which may be partially responsible for chemotherapy-induced vomiting progression.We thus examined whether balance correlates with incidence and/or risk factors chemotherapyinduced nausea and (CINV) in women CINV factor) inpatients receiving treatment...
Tramadol is a weak opioid analgesic indicated for the treatment of moderate to severe cancer pain at step 2 WHO ladder. There little experience its use in Japan; there are few reported detailed surveys on usage tramadol and usefulness patients who changed from taking stronger opioids. The present study included inpatients took hydrochloride capsule Nagoya University Hospital between October 2011 March 2014; these were retrospectively examined based electronic medical records. We observed...