A5108748270- Acute Kidney Injury Research
- Antioxidant Activity and Oxidative Stress
- Dialysis and Renal Disease Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Parathyroid Disorders and Treatments
- Magnesium in Health and Disease
- Blood properties and coagulation
- Chronic Kidney Disease and Diabetes
- Immunotherapy and Immune Responses
- Cutaneous Melanoma Detection and Management
- RNA modifications and cancer
- Mast cells and histamine
- Biological Activity of Diterpenoids and Biflavonoids
- bioluminescence and chemiluminescence research
- Bioactive Compounds and Antitumor Agents
- Thyroid and Parathyroid Surgery
- Melanoma and MAPK Pathways
- Cancer Mechanisms and Therapy
- Cancer, Lipids, and Metabolism
- Hereditary Neurological Disorders
- Medicinal Plants and Bioactive Compounds
- Agriculture, Soil, Plant Science
- Neonatal and Maternal Infections
- Heavy Metal Exposure and Toxicity
- Cardiac Valve Diseases and Treatments
Chongqing Cancer Hospital
2025
Chongqing University
2025
Jilin Agricultural University
2024
Jiangnan University
2012-2021
Sichuan University
2016-2020
West China Hospital of Sichuan University
2016-2020
Hebei Medical University
2012-2020
Second Hospital of Hebei Medical University
2014-2020
Army Medical University
2014-2019
Illawarra Health and Medical Research Institute
2015
Malignant melanoma is a rare disease in Asia, and knowledge on its characteristics clinical outcome Asian patients limited. The purpose of this observational study was to determine the presentation with China.A database prospectively established for analysis. elements included basic demographic data prognosticators previously reported literature, as well follow-up including after treatment. Medical record all pathologically diagnosed malignant consulted our center since 2006 were retrieved...
KIT aberrations were described in acral and mucosal melanomas largely Caucasian populations. Asian populations are more prone to develop than cutaneous melanomas, may harbor a high frequency of aberrations.Melanoma subtypes (n = 502) analyzed histologically determine melanoma subtype. Tissue samples for mutations exons 9, 11, 13, 17, 18 gene genomic DNA by PCR amplification Sanger sequencing. The copy numbers the quantitative PCR, protein expression levels (CD117) determined...
Neutrophil gelatinase associated lipocalin (NGAL) is a highly predictive biomarker of acute kidney injury. To understand the role NGAL in renal injury during sepsis, we investigated temporal changes and biological sources rat model injury, explored relationship between inflammation, humoral expression endotoxemia.To induce rats were treated with lipopolysaccharide (LPS, 3.5 mg/kg, ip), location mRNA was evaluated by situ hybridization. Quantitative RT-PCR also used to determine dynamic NGAL,...
Nitrogen (N) is the primary essential nutrient for ginseng growth, and a reasonable nitrogen application strategy vital maintaining stability of soil microbial functional communities. However, how microbial-mediated genes involved in cycling rhizosphere respond to addition largely unknown. In this study, metagenomic technology was used study effects different additions (N0: 0, N1: 20, N2: 40 N g/m
Carotenoids produced by Sporidiobolus pararoseus were studied. It was found that biomass connected with carbon source, temperature, and pH, but carotenoids proportion seriously influenced dissolved oxygen nitrogen source. Different could be obtained using selected optimum conditions. In the end we established strategies to produce β-carotene or torulene. Fed-batch fermentation in fermentor used prove authenticity of our conclusions. The cell biomass, content, reach 56.32 g/L, 18.92 mg/L...
Abstract Introduction: There is no consensus on the specific indications for weaning critically ill patients with acute kidney injury (AKI) off renal replacement therapy (RRT). This study aimed to explore prognostic value of several biomarkers measured upon discontinuation RRT their in predicting 60‐day survival and recovery an effort add knowledge decision‐making process regarding withdrawal. Methods: We prospectively enrolled 102 AKI who required from intensive care unit. Serum osteopontin...
We sought to confirm that neutrophil gelatinase-associated lipocalin (NGAL) protects against apoptosis during endotoxemia. Endotoxemia was induced in rats with lipopolysaccharide (LPS; 3.5 mg/kg) and serum creatinine (SCr), urinary NGAL (uNGAL), renal histopathology confirmed acute kidney injury (AKI). Renal caspase 3 were assayed immunohistochemistry 6 h later. A HK-2 cell model used which mRNA evaluated by qRT-PCR within after LPS (50 μM) treatment, correlations studied. expression...
Guillain-Barré syndrome (GBS) is an autoimmune condition characterized by peripheral neuropathy. The pathogenesis of GBS not fully understood, and the mechanism how intravenous immunoglobulin (IVIG) cures ambiguous. Herein, we investigated lymphocyte subsets in patients with two major subtypes (acute inflammatory demyelinating polyneuropathy, AIDP, acute motor axonal neuropathy, AMAN) before after treatment IVIG, explored possible IVIG action.Sixty-four were selected for our study divided...
Torulene, inhibit LNCaP and PC-3 cells growth through Bcl-2/Bax mediated apoptosis AR down-regulation.
Abstract Aim Vascular calcification (VC) is a common complication in chronic kidney disease (CKD) and has been shown to be associated with increased cardiovascular events mortality. This study was explore the role of Wnt‐signaling pathway CKD VC, association between VC blood pressure variability (BPV) which risk factor events. Methods Adult male Sprague‐Dawley rats were divided into adenine‐induced group (n = 5), 5/6 nephrectomy sham 5) control 5). Low‐calcium‐high‐phosphate diets introduced...
Abstract The specific timing for discontinuing renal replacement therapy (RRT) in acute kidney injury (AKI) patients is debatable. predictive abilities of variables at the time discontinuation RRT long‐term prognoses have not been explored. This study aimed to explore prognostic factors upon chronic dialysis and death with RRT‐requiring AKI, thus improving decision making regarding follow‐up thereafter. A cohort 302 AKI who required remained alive free least 30 days after discharge from...
Torularhodin is one of the principal carotenoids in<italic>Sporidiobolus pararoseus</italic>and has a similar structure to that lycopene.
Abstract Coronary artery calcifications (CACs) are common among maintenance hemodialysis (MHD) patients and associated with increased morbidity mortality due to cardiovascular events. The insight into chronic kidney disease‐mineral bone disorder (CKD‐MBD) established a correlation between dysregulated mineral metabolism CACs. This study aimed identify the association of content outside (MCOB) CACs events in MHD patients. In pilot prospective no intervention, underwent body composition...
Objective: In this study, we aimed to search for noninvasive predictive biomarkers prenatal diagnosis of Down's syndrome (DS). Methods: Maternal serum samples from five DS-affected pregnant women and DS-unaffected were analyzed by 2D gel electrophoresis MALDI-TOF mass spectrometry screen potential DS. Then, differential levels dGTPase, β2-glycoprotein I (β2-GPI), complement factor H-related protein 1 precursor (CFHR1) kininogen isoform 2 further verified western blotting tests in another...
Diabetic nephropathy (DN) is the major life-threatening complication of diabetes, and oxidative stress takes part in its initiation development. This study was performed to evaluate effects carotenoids from Sporidiobolus pararoseus (CSP) on renal function status mice with streptozotocin (STZ)-induced DN. The results indicated that CSP significantly attenuated symptoms STZ-induced DN shown by decreased fasting blood glucose, reduced urine volume, albumin, serum creatinine urea nitrogen,...
Correction for ‘Torularhodin, isolated from <italic>Sporidiobolus pararoseus</italic>, inhibits human prostate cancer LNCaP and PC-3 cell growth through Bcl-2/Bax mediated apoptosis AR down-regulation’ by Chao Du <italic>et al.</italic>, <italic>RSC Adv.</italic>, 2015, <bold>5</bold>, 106387–106395.