A5046653171- Molecular Sensors and Ion Detection
- Protein Interaction Studies and Fluorescence Analysis
- Luminescence and Fluorescent Materials
- Advanced biosensing and bioanalysis techniques
- Lanthanide and Transition Metal Complexes
- Electrochemical sensors and biosensors
- Biosensors and Analytical Detection
- Analytical Chemistry and Sensors
- Drug Transport and Resistance Mechanisms
- Sulfur Compounds in Biology
- Nanoplatforms for cancer theranostics
- Advanced Chemical Sensor Technologies
- Fuel Cells and Related Materials
- Chromatography in Natural Products
- Electron Spin Resonance Studies
- Natural product bioactivities and synthesis
- Antibiotics Pharmacokinetics and Efficacy
- Electrochemical Analysis and Applications
- Analytical chemistry methods development
- Medicinal Plant Pharmacodynamics Research
- Traditional Chinese Medicine Analysis
- Conducting polymers and applications
- Advanced Nanomaterials in Catalysis
- Pharmacological Effects and Assays
- Food Quality and Safety Studies
Shenzhen University
2016-2025
Huaqiao University
2004-2024
State Key Laboratory of Fine Chemicals
2024
Nanjing Medical University
2017-2024
Liaoning University
2009-2023
Foshan University
2019-2023
Shanxi Medical University
2023
Shanghai University
2023
Nanjing Tech University
2023
Dalian University of Technology
2022
An aqueous ratiometric ESIPT sensor with a 87 nM (15.4 ppb) detection limit was successfully synthesized and applied for of all oxidation states palladium species.
We have designed and synthesized a novel ratiometric fluorescent chemodosimeter MHF-based ESIPT process for specific detection of cysteine among the biological thiols. The probe MHF shows very weak blue fluorescence under UV excitation. Upon addition (Cys), reaction Cys with induces acrylate hydrolysis, thereby enabling to shift emission strong green about 20-fold enhancement. utilized (1)H NMR spectra elucidate sensing mechanism. Moreover, cellular imaging experiment indicated possessed...
A series of bishydrazide compounds have been developed for selective turn-on detection Al3+ cation, based on metal chelation-enhanced fluorescence (CHEF) effects that inhibit the nonradiative PET and ESIPT processes. In aqueous solution, selectively induces strong these with large Stokes shifts up to ∼133 nm emission colors varying from blue orange. solid phase, both Zn2+ give apparent which is simultaneously detected chromatographic separation.
Low-temperature photothermal therapy (PTT) systems constructed by integrating organic agents with other bactericidal components that initiate bacterial apoptosis at low hyperthermia possess a promising prospect. However, these multicomponent low-temperature PTT nanoplatforms have drawbacks in terms of the tedious construction process, suboptimal synergy effect diverse antibacterial therapies, and high laser dose needed, compromising their biosafety ocular infection treatment. Herein, mild...
Robust, highly thermally stable, MOx/(MOx–SiO2)/SiO2 core–shell nanostructured metal oxide aerogels with a MOx core and (MOx–SiO2)/SiO2 shell are produced via novel alkoxide chemical liquid deposition techniques. The nanostructure not only significantly reinforces the nanoparticles but also effectively inhibits crystal growth phase transition of upon heat treatment, which enhances resistance from approximate 400–800 °C up to 1000–1300 °C. resultant Al2O3, ZrO2, TiO2 can support at least 5800...
A colorimetric and ratiometric fluorescent chemosensor for F− has been prepared, which is based on combination of desilylation reaction excited-state proton transfer from the product to F−. The sensor exhibits rapid response, excellent selectivity sensitivity
Abstract Monitoring of human serum albumin (HSA) in a point‐of‐care fashion is urgently needed particular for elderly or chronically ill patients. Herein, dual‐state emissive chalcone probe having the feature aggregation‐induced emission was designed and synthesized. The concentration HSA can be evaluated by ratios from probes aggregated monomeric state, which gives visually discernible red‐to‐green color change. A simple, portable paper‐based analytical device have been fabricated...
The development of highly effective photosensitizers (PSs) for photodynamic therapy remains a great challenge at present. Most PSs rely on the heavy-atom effect or spin-orbit charge-transfer intersystem crossing (SOCT-ISC) to promote ISC, which brings about additional cytotoxicity, and latter is susceptible interference solvent environment. Herein, an immanent universal property named photoinduced molecular vibrational torsion (PVT)-enhanced coupling (PVT-SOC) in has been first revealed. PVT...
A novel conjugated polymer chemosensor 1 containing 2,6-bis(2-thienyl)pyridine has been synthesized and exhibits a high sensitivity selectivity for palladium ion detection based on the fluorescent quenching effect.
A novel well-defined amphiphilic fluorescent polymer containing asymmetric perylene bisimide was designed and synthesized by combining reaction of anhydride with amino functional polyhedral oligomeric silsesquioxane (POSS) atom transfer radical polymerization (ATRP) N-isopropylacrylamide (NIPAM). All the intermediate final products were characterized NMR, Fourier transform infrared spectroscopy (FT-IR), elemental analyses, gel permeation chromatograph (GPC). Self-assembly polymers...
The fluorescence pattern of proteins in the polyacrylamide gel by using flavone dye staining without washing process.
Based on the aggregation-induced fluorescence quenching mechanism, a 2,6-dithienyl-4-phenylpyridine-containing conjugated polymer (P-A) has been designed and synthesized via Sonogashira coupling reaction as an efficient fluorescent sensor for palladium platinum ions. The metal ion-sensitivity of P-A was evaluated using series transition ions in aqueous solution. On binding to Pd2+ or Pt4+, demonstrated by approximately 80% reduction intensity, while no obvious change could be observed...
Green-emitting flavonoids were found to selectively accumulate in the endoplasmic reticulum (ER), giving fluorescence turn on.