- Intracranial Aneurysms: Treatment and Complications
- Cerebrovascular and Carotid Artery Diseases
- Vascular Malformations Diagnosis and Treatment
- Acute Ischemic Stroke Management
- Moyamoya disease diagnosis and treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Glioma Diagnosis and Treatment
- Neurosurgical Procedures and Complications
- Cerebrospinal fluid and hydrocephalus
- Meningioma and schwannoma management
- Antibiotic Resistance in Bacteria
- Intracerebral and Subarachnoid Hemorrhage Research
- Phenothiazines and Benzothiazines Synthesis and Activities
- Brain Metastases and Treatment
- Cerebral Venous Sinus Thrombosis
- Spinal Fractures and Fixation Techniques
- Antibiotics Pharmacokinetics and Efficacy
- Silk-based biomaterials and applications
- Aortic Disease and Treatment Approaches
- Synthesis of β-Lactam Compounds
- Peripheral Artery Disease Management
- Neuroblastoma Research and Treatments
- Silkworms and Sericulture Research
- Bone Tumor Diagnosis and Treatments
- Synthesis and Biological Evaluation
Dokkyo Medical University Saitama Medical Center
2016-2025
Social Insurance Saitama Chuo Hospital
2018-2025
Dokkyo Medical University
2010-2024
Dokkyo University
2010-2024
Neurological Surgery
1987-2022
Stony Brook University
2022
Shinshu University
2022
Fukushima Medical University
2021
Southern Tohoku General Hospital
2021
Nara Medical University
2018
Journal Article Studies on Silk Fibroin of Bombyx mori. I. Fractionation Prepared from the Posterior Gland Get access Kensuke SHIMURA, SHIMURA Laboratory Biochemistry, Department Agricultural Chemistry, Tohoku UniversitySendai, Miyagi 980 Search for other works by this author on: Oxford Academic PubMed Google Scholar Aiko KIKUCHI, KIKUCHI Kohei OHTOMO, OHTOMO Yōtarō KATAGATA, KATAGATA Akio HYODO The Volume 80, Issue 4, October 1976, Pages 693–702,...
Ischemic stroke is a leading cause of death and disability worldwide. Much the long-term occurs in patients with Emergent Large Vessel Occlusion (ELVO). In fact, these patients, occlusion major intracerebral artery results large area brain injury often resulting
Symptomatic unruptured aneurysms have been considered at relatively high risk for future rupture, and the majority of that cause symptoms mass effect are large. Unruptured smaller than 1 cm in diameter sometimes neurological symptoms, but their clinical aspects remain obscure. In this article, we review our experience with small presenting oculomotor nerve palsy.Sixteen patients palsy were included study. The patients' profiles reviewed, factors affecting recovery function determined.The...
✓ Seventy-six splenectomized dogs were entered in a study of the value and effects isovolemic hemodilution. Of these, seven not included analysis because technical errors. remaining 69 dogs, 35 treated with hemodilution; 28 subjected to 6-hour period temporary occlusion distal internal carotid artery proximal middle cerebral artery, underwent sham operation only, arterial manipulation but no occlusion. The other 34 26 these eight had only. In each group animals about equally divided into 1)...
A total of 76 splenectomized dogs were entered in a study the value and effects isovolemic hemodilution. Of these, seven not included analysis because technical errors. remaining 69 dogs, 35 treated with hemodilution; 28 subjected to 6-hour period temporary occlusion distal internal carotid artery proximal middle cerebral artery, underwent sham operation only, arterial manipulation but no occlusion. The other 34 26 these eight had only. In each group animals about equally divided into 1) an...
Journal Article Inhibition of β-lactamases by tazobactam and in-vitro antibacterial activity combined with piperacillin Get access Fusahiro Higashitani, Higashitani * aEpisome Institute, Fujimi-muraSeta-gun, Gunma *Corresponding author: c/o Episome 2220 Fujimi-mura kogure, Seta-gun, Gunma, Japan Search for other works this author on: Oxford Academic PubMed Google Scholar Akio Hyodo, Hyodo bTaiho Pharmaceutical Co. LtdTokushima Naofumi Ishida, Ishida Matsuhisa Inoue, Inoue cSchool Medicine,...
✓ Forty dogs were subjected to 6 hours of occlusion the left internal carotid and middle cerebral arteries. They divided into two “hemodilution groups” 13 each a control “nonhemodiluted group” 14 dogs. Thirty minutes after arterial occlusion, isovolemic hemodilution was performed by phlebotomy infusions low-molecular weight (MW) dextran in one group lactated Ringer's solution other group. The animals sacrificed 1 week temporary occlusion. Hemodilution reduced hematocrit level 33% 34%, which...
Brain metastases from gynecological cancers were retrospectively investigated in 18 patients who treated between 1985 and 2006. Six received surgical resection followed by radiotherapy, 12 only radiotherapy. The median survival for all was 4.1 months (range 0.7-48.2 months), the actuarial rates 11% at both 24 months. Univariate analysis showed that treatment modality, extracranial disease status, total radiation dose, number of brain metastases, Karnofsky performance status (KPS) had...
The present study retrospectively analyzed the database of Japanese Registry Neuroendovascular Therapy 1 and 2 (JR-NET1&2) to determine annual trends, including adverse events clinical outcomes at 30 days after undergoing neuroendovascular therapy. JR-NET1&2 are surveys that targeted all patients in Japan who underwent therapy delivered by physicians certified Society (JSNET) between 2005 2009. Medical information about was anonymized registered via a website. Data from 32,608 were analyzed....
Multinodular and vacuolating neuronal tumors (MVNT) have been recently referred to as a distinctive tumor entity based on histopathological findings. They are characterized by multiple nodules, vacuolar alteration widespread immunolabeling for human protein HuC/HuD. Only 13 cases reported in the literature date little is known about histopathology of these tumors. Herein, we report case MVNT with additional confirmation immunohistochemical features. A 22‐year‐old woman presented continuous...
Background The dual-layer nitinol CASPER stent was designed to prevent plaque prolapse into its strut and periprocedural stroke. Objective To conduct a clinical trial for government approval of the device in patients at either high or normal risk carotid endarterectomy (CEA). Methods Eligible had ≥50% symptomatic stenosis ≥80% asymptomatic according North American Symptomatic Carotid Endarterectomy Trial methods (peak systolic velocity 130 230 cm/s on ultrasonography, respectively). primary...
Studies have demonstrated the effectiveness of hydrogel-coated coils (HGCs) to achieve composite endpoint decreased recanalization rates and greater safety. Herein, authors aimed assess true ability second-generation HGCs prevent recanalization. This randomized controlled study, HYBRID (Hydrocoil Versus Bare Platinum Coil in Recanalization Imaging Data) trial, comparing with bare platinum (BPCs), was conducted 43 Japanese institutions. The aneurysm diameter range 7-20 mm. were used 4...
Fibroin is normally composed of one H chain (350 kd) and L (25 which are connected by disulfide bond(s). However, the small amount fibroin secreted into lumen posterior silk gland Nd(2) (naked pupa) mutant does not contain chain, although mRNA present synthesized in cells mutant. In a hybrid silkworm, Nd(2)/Tamanashikasuri, where Tamanashikasuri normal producer fibroin, from two alleles distinguishable electrophoretically. It demonstrated using this system that allele can combine with H-L...
Intracranial pseudoaneurysms are uncommon and among the most difficult lesions to treat with surgery or endovascular means without parent artery sacrifice. Here, we report on a patient who underwent successful treatment using flow-diverting stent for an iatrogenic intracranial internal carotid pseudoaneurysm following vessel injury after endoscopic pituitary tumor resection via transsphenoidal approach. A 62-year-old man Rathke’s cleft cyst presenting bitemporal hemianopia progressive...
Application of thermosensitive polymers as an embolic material for intravascular neurosurgery was investigated. We intended to use occlude vessels by precipitation in response body temperature. Copolymers N-isopropylacrylamide (NIPAM) and N-n-propylacrylamide (NPAM) were selected polymers. To determine the optimal lower critical soluble temperature (LCST) material, we developed vitro flow model. In this study copolymers with LCST 24-26 degrees C showed appropriate precipitation. prove...
We used 44 splenectomized dogs to study the effects of isovolemic hemodilution with a crystalloid solution. The were randomly divided into and control group. In each group, 17 subjected 6 hours internal carotid middle cerebral artery occlusion, five received sham operations. Isovolemic by phlebotomy Ringer's lactate infusion was performed 30 minutes after arterial occlusion resulted in an average hematocrit 32-33%. Hemodilution significantly reduced viscosity, fibrinogen total protein...