A5014294821- Glaucoma and retinal disorders
- Corneal surgery and disorders
- Ocular Surface and Contact Lens
- Retinal Diseases and Treatments
- Retinal and Optic Conditions
- Cerebral Venous Sinus Thrombosis
- Retinal Imaging and Analysis
- Ophthalmology and Visual Impairment Studies
- Corneal Surgery and Treatments
- Herpesvirus Infections and Treatments
- Intraocular Surgery and Lenses
- Virus-based gene therapy research
- Ocular Infections and Treatments
- Neurosurgical Procedures and Complications
- Hemoglobinopathies and Related Disorders
- Retinopathy of Prematurity Studies
- Retinal Development and Disorders
- Ophthalmology and Eye Disorders
- Older Adults Driving Studies
- Iron Metabolism and Disorders
- Ocular Oncology and Treatments
- Facial Rejuvenation and Surgery Techniques
- Traffic and Road Safety
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac, Anesthesia and Surgical Outcomes
Washington University in St. Louis
2015-2024
Columbia University Irving Medical Center
2023
St. Louis Children's Hospital
2023
Wake Forest University
2022
University of California, San Diego
2021
The Ohio State University
1996-2019
Sunshine Coast University Hospital
2018
Prevent Blindness
2012
Stanford University
2010
University of Washington
2008
<h3>Background</h3> The Ocular Hypertension Treatment Study (OHTS) has shown that topical ocular hypotensive medication is effective in delaying or preventing the onset of primary open-angle glaucoma (POAG) individuals with elevated intraocular pressure (ocular hypertension) and no evidence glaucomatous damage. <h3>Objective</h3> To describe baseline demographic clinical factors predict which participants OHTS developed POAG. <h3>Methods</h3> Baseline data were collected prior to...
Silent cerebral infarcts are the most common neurologic injury in children with sickle cell anemia and associated recurrence of an infarct (stroke or silent infarct). We tested hypothesis that incidence would be lower among who underwent regular blood-transfusion therapy than those received standard care.In this randomized, single-blind clinical trial, we randomly assigned to receive blood transfusions (transfusion group) care (observation group). Participants were between 5 15 years age, no...
<h3>Background</h3> The Ocular Hypertension Treatment Study (OHTS) seeks to evaluate the safety and efficacy of topical ocular hypotensive medication in preventing or delaying onset visual field loss and/or optic nerve damage subjects with hypertension at moderate risk for developing primary open angle glaucoma. <h3>Objective</h3> To describe study protocol, questions be answered, baseline characteristics subjects. <h3>Design</h3> Multicenter randomized clinical trial 2 groups: close...
We examined the influence of glaucomatous visual field defects on vision-targeted and generic health-related quality life. Vision-targeted health status were assessed across 5 glaucoma treatment categories a normal reference group from tertiary care ophthalmology practices during regularly scheduled eye visits. The sample consisted 147 patients who members specific 44 patients. For with glaucoma, eligibility included diagnosis at least 1 year prior to enrollment no evidence other disease....
<h3>Objectives</h3> (1) To develop a classification system for visual field (VF) abnormalities, (2) to determine interreader and test-retest agreement, (3) the frequency of various VF defects in Ocular Hypertension Treatment Study. <h3>Methods</h3> Follow-up VFs are performed every 6 months monitored abnormality, indicated by glaucoma hemifield test result or corrected pattern SDoutside normal limits. As January 1, 2002, 1636patients had 2509 abnormal VFs. Three readers independently...
<h3>Objective</h3> To determine the frequency with which visual field abnormalities observed on follow-up fields for patients in Ocular Hypertension Treatment Study were confirmed retest. <h3>Methods</h3> Between April 1, 1994, and March 1999, 21,603 obtained from 1637 Study. When are outside normal limits Glaucoma Hemifield Test, Corrected Pattern Standard Deviation (<i>P</i><.05), or both, subsequent monitored to confirm abnormality. Abnormalities if they again abnormal Deviation, both;...
To compare the safety and efficacy of earlier vs later treatment in preventing primary open-angle glaucoma (POAG) individuals with ocular hypertension.One thousand six hundred thirty-six intraocular pressure (IOP) from 24 to 32 mm Hg 1 eye 21 fellow were randomized observation or topical hypotensive medication. Median time medication group was 13.0 years. After a median 7.5 years without treatment, received for 5.5 determine if there is penalty delaying we compared cumulative proportions...
Background: Patients with neuromyelitis optica (NMO) and multiple sclerosis (MS) both can present acute optic neuritis (ON), while differing considerably in their prognosis management. The clinical course, serologic testing results, brain spinal cord imaging of these diseases have been well documented. purpose this study was to look systematically for any differences the appearance nerve NMO MS-related ON. Methods: Magnetic resonance (MRI) orbits obtained within 6 weeks ON patients securely...
Vitrectomy is associated with the rapid progression of nuclear cataracts. This study was conducted to test hypothesis that age-related liquefaction vitreous gel may also be lens opacification.Lenses from eye bank eyes were graded for nuclear, cortical, and posterior subcapsular opacities, amount liquid measured.Nuclear sclerosis (NS) grade, percent liquefaction, age all correlated highly (P < 0.0001). After adjustment made age, correlation between NS 0.37 0.0001), after 0.57 stratified into...
The multicenter Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study is a prospective, observational study 1209 keratoconus patients. We report methods to define incident corneal scarring and baseline factors predictive in nonsurgical eyes CLEK patients through their fifth year follow-up. Of the 1,209 patients, 878 with at least one unscarred cornea were included this study. cumulative 5-year incidence defined as proportion who developed central opacification detected by...
Cerebral palsy (CP) is a permanent, nonprogressive disorder of movement and posture due to lesion the fetal or infant brain. The goal was determine whether children with different severities CP, as defined using Gross Motor Function Classification System (GMFCS), had degrees types visual dysfunction.An observational, cross-sectional-design study conducted by neurologic masked ophthalmic measurements on representative cohort 50 CP. Mean age 5.6 years (range, 2-19.5 years); mean gestational 31...