A5101536050- Liver Disease Diagnosis and Treatment
- Inflammatory Bowel Disease
- Microscopic Colitis
- Pancreatic and Hepatic Oncology Research
- Pancreatitis Pathology and Treatment
- Multiple Sclerosis Research Studies
- Traditional Chinese Medicine Analysis
- Organ Transplantation Techniques and Outcomes
- Cancer Mechanisms and Therapy
- Diabetes and associated disorders
- Infectious Encephalopathies and Encephalitis
- Liver Disease and Transplantation
- Gallbladder and Bile Duct Disorders
- Autoimmune Neurological Disorders and Treatments
- Epilepsy research and treatment
- Clinical Nutrition and Gastroenterology
- Cancer-related Molecular Pathways
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Lymphoma Diagnosis and Treatment
- Long-Term Effects of COVID-19
- Pediatric Hepatobiliary Diseases and Treatments
- Ophthalmology and Eye Disorders
- Thyroid Disorders and Treatments
- Inflammatory Myopathies and Dermatomyositis
- Liver physiology and pathology
Southern Medical University
2025
Xijing Hospital
2019-2025
Air Force Medical University
2019-2025
PowerChina (China)
2025
Children's Hospital of Fudan University
2008-2024
Shandong Provincial Hospital
2024
Shandong First Medical University
2023-2024
Hebei Medical University
2022-2023
Second Hospital of Hebei Medical University
2022-2023
Tulane University
2022-2023
It has been proposed that pancreatic beta-cell dysfunction in type 2 diabetes is promoted by oxidative stress caused NADPH oxidase (Nox) over-activity. The aim of the present study was to evaluate efficacy novel Nox inhibitors as protective agents against cytokine- or high glucose + palmitate-induced human death. Nox2 protein mainly cytoplasm and induced cytokines. Nox4 immunoreactivity, with some nuclear accumulation, observed islet cells, not affected culture presence cytokines palmitate....
To characterise the peripheral blood cell (PBC) gene expression changes ensuing from mycophenolate mofetil (MMF) or cyclophosphamide (CYC) treatment and to determine predictive significance of baseline PBC transcript scores for response immunosuppression in systemic sclerosis (SSc)-related interstitial lung disease (ILD).
Background Patients with ulcerative colitis (UC) are at an increased risk of developing Clostridioides difficile infection (CDI), which in turn leads to poor outcomes. The gut microbial structure and metabolites patients UC CDI have been scarcely studied. We hypothesized that changes the microbiota UC. Materials Methods This study included 89 patients: 30 healthy controls (HC group), 29 alone (UCN (UCP group). None participants has exposed antibiotic treatments during 3 months before stool...
Choledochal cyst is rare in western countries. The relatively high incidence of coexistent hepatobiliary disease increases the difficulty surgical management choledochal cyst. Here we analyze diagnosis and treatment congenital bile duct 122 Chinese adults.The clinical data patients with cysts admitted from 1981 to 2006 were analyzed.Clinical symptoms most cases nonspecific, resulting delayed diagnosis. Sixty-one (50%) had pancreatobiliary disease. Among patients, 119 underwent ultrasonic...
Early adequate feeding reduces mortality in patients with acute severe stroke. Supplemental parenteral nutrition (SPN) may address enteral (EN) deficiency and mitigate the risk of nosocomial infection. The benefit EN plus early SPN strategy over full is unknown stroke patients. We retrospectively enrolled 20 group who received (more than 50% energy target within 72 h after admission). Forty control were matched by age, sex lesion site. time to new-onset pneumonia or infections was analyzed...
Background: Renal vascular lesions (RVLs) are a common histopathological feature in lupus nephritis(LN). Despite their frequent occurrence, the clinical significance and prognostic impact of RVLs remain poorly understood. The main objectives our study were to investigate clinicopathological characteristics associated with LN assess implications patients LN. Methods: We conducted retrospective analysis baseline pathological data, as well outcomes, for diagnosed biopsy-confirmed between...
Autoimmune thyroid disease (AITD) comprises Graves' (GD) and Hashimoto's thyroiditis (HT). IL37 has been recently proved to be a natural suppressor for innate immunity acquired immunity. Therefore, this study was conducted identify the association of genetic polymorphisms with AITD in Chinese Han population. Polymorphisms rs3811046/rs3811047/rs2723176/rs272186 gene were assessed case–control comprising 701 GD patients, 301 HT patients 939 controls. Genetic variants genotyped by multiplex...
Frequency‐domain soil parameters have an important influence on the response of earthing systems subject to impulse current. To estimate frequency domain horizontal multi‐layered effectively and quickly, a novel estimation strategy based nonhomogeneous cuckoo search algorithm (NoCuSa) is proposed. Firstly, NoCuSa applied for estimating electrical soils, with their performance verified by software CDEGS (Current Distribution, Electromagnetic Fields, Grounding, Soil Structure Analysis) in DC...
PV241 / #806 Poster Topic: AS23 - SLE-Diagnosis, Manifestations, & Outcomes Background/Purpose Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease that can involve multiple organ systems, including the kidneys, blood, and skin. Nephritis (LN) most severe complication of SLE, with treatment objectives aimed at preventing kidney (CKD) End-Stage Renal Disease (ESRD), optimizing quality life, improving survival. Anemia common hematologic in SLE closely associated activity,...
The purpose of this study was to describe the epidemiology nosocomial candidemia and identify risk factors involved in infections caused by non-C. albicans Candida species a Chinese tertiary care center over 10-year period. A total 102 cases non-neutropenic patients admitted from 1998 through 2007 were included study. remained most common causative agent, accounting for 57.8% all cases, followed C. tropicalis (12.8%), parapsilosis (10.8%) glabrata (10.8%). Comparison multivariate logistic...
Kaempferol, a flavonoid derived from various herbs such as cocoyam, propolis, and grapefruit, has garnered interest due to its numerous pharmacological benefits, including anti-inflammatory, antioxidant, anti-diabetic properties. Kaempferol been shown possess notable anti-tumour bioactivity, indicating potential for treating gynaecological malignancies. To date, studies have demonstrated the of kaempferol induce tumour cell apoptosis, inhibit proliferation, prevent metastasis invasion in...
Treatment of microcystic lymphatic malformations (LMs) is still a great challenge to physicians in the field managing vascular anomalies. Several kinds treatment have been proposed for LMs, but responses these modalities vary considerably among individuals. The aim study was investigate safety and efficacy intralesional injection pingyangmycin LMs located deep facial region. Twenty-one consecutive patients with deep-seated were treated between March 2010 April 2015. received 2 8 injections,...
The first-line chemotherapy regimen for advanced gallbladder cancer (GBC) is gemcitabine plus platinum (GP), despite its efficacy limited. current investigation a retrospective study to compare the safety and between modified FOLFIRINOX (mFOLFIRINOX) oxaliplatin (GEMOX) as unresectable locally or metastatic GBC.The data of patients with GBC, who were treated mFOLFIRINOX GEMOX therapy April 2014 2018 at Xinhua Hospital Affiliated Shanghai Jiaotong University School Medicine, retrieved. This...