A5102015643- Neuropeptides and Animal Physiology
- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Long-Term Effects of COVID-19
- Nitric Oxide and Endothelin Effects
- COVID-19 Clinical Research Studies
- IgG4-Related and Inflammatory Diseases
- Neonatal and Maternal Infections
- Neonatal Respiratory Health Research
- Glycosylation and Glycoproteins Research
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Gold and Silver Nanoparticles Synthesis and Applications
- Cardiovascular Issues in Pregnancy
- Signaling Pathways in Disease
- SARS-CoV-2 and COVID-19 Research
- Biochemical effects in animals
- Eicosanoids and Hypertension Pharmacology
- Shoulder Injury and Treatment
- RNA modifications and cancer
- Orthopaedic implants and arthroplasty
- Atherosclerosis and Cardiovascular Diseases
- Immune Cell Function and Interaction
- Ion Channels and Receptors
Fujian Medical University
2015-2025
Center for Disease Control
2024
Southern Medical University
2022
Nanfang Hospital
2022
Central South University
2001-2018
Fuzhou General Hospital of Nanjing Military Command
2015-2018
Chinese University of Hong Kong
2018
University of Hong Kong
2018
National University of Defense Technology
2018
Guangxi Medical University
2015
The pathogenesis of osteosarcoma involves complex genetic and epigenetic factors. This study was to explore the impact clinical relevance long non-coding RNA (lncRNA), Taurine up-regulated gene 1 (TUG1) on patients with osteosarcoma. Seventy-six tissues matched adjacent normal were included for analysis. plasma samples obtained from 29 at pre-operation post-operation, 42 newly diagnosed, 18 who experienced disease progression or relapse, 45 post-treatment, 36 benign bone tumor, 20 healthy...
The present study successfully developed a method based on dual-functional probe for detecting breast cancer cells MCF-7 by recognizing the MUC1 protein cell surface. This integrated inductively coupled plasma mass spectrometry (ICP-MS) and fluorescence imaging technology, enhancing sensitivity, specificity, accuracy of detection. Additionally, through two-sample Mendelian randomization (MR) analysis, we verified potential correlation between (PIVW<0.05), while also proving no liver...
<b><i>Background/Aims:</i></b> Nattokinase is a serine protease produced by <i>Bacillus subtilis</i> during the fermentation of soybean product natto. The fibrinolytic activity and thrombolytic effects nattokinase have been observed in vitro, but effect vivo has still to be researched. objective this study was demonstrate vivo. <b><i>Methods:</i></b> To establish rat model thrombosis, &#954;-carrageenan injected subcutaneously...
Yulangsan polysaccharide (YLSP) is a traditional Chinese medicine used in long-term treatment as modulator of brain dysfunction and immunity.
Abstract Background The aim of this study was to investigate the effects Resveratrol (RSV) in rats with dilated cardiomyopathy (DCM). Methods Porcine cardiac myosin used set up rat model DCM. RSV (10 mg/kg RSV-L group and 50 RSV-H group) or vehicle administered DCM once daily from 28th day till 90th after first immunization. Cardiac function evaluated by echocardiographic analysis. deposition fibrous tissues hearts Masson picrosirius red staining. mRNA levels collagen type I (Col I), III...
To track the level of serum antibodies in Fuzhou residents and analyze possible influencing factors antibodies, so as to provide a scientific basis for adjustment population immunity prevention control strategies. Residents community who had symptoms covid-19 infection or tested positive nucleic acid antigen since December 2022 were selected questionnaire survey their sera collected trend antibody changes, was divided into high group low according literature data. The analyzed by...
The incidence of secondary displacement in fractures the greater tuberosity humerus remains high, irrespective whether conservative or surgical treatment is administered. However, specific risk factors contributing to have not been previously reported. primary objective this study was analyze associated with and summarize corresponding guidelines for clinical diagnosis treatment. A retrospective analysis conducted on patients who received at same trauma center between January 2018 December...
Sleep disturbance has become a significant concern among college students, as it can lead to various mental and physical disorders. This study aims provide fresh perspective by developing validating predictive model for sleep quality students. Data from 20,645 students in Fujian Province, China, collected between 5th April 16th 2022, were analyzed. Participants completed the Pittsburgh Quality Index (PSQI) scale, self-designed general data questionnaire, influencing factor questionnaire....
High serum lactate dehydrogenase and dyspnea: Positive predictors of adverse outcome in critical COVID-19 patients Yichang
Abstract Objective To examine potential associations of the Glu/Asp 298 polymorphism in exon 7 and 4a/b intron 4 endothelial nitric oxide synthase (eNOS) gene with susceptibility to clinical expression giant cell arteritis (GCA), particularly patients versus those without ischemic complications. Methods Ninety‐one consecutive biopsy‐proven GCA, who were residents Reggio Emilia, Italy, 133 population‐based controls from same geographic area genotyped by polymerase chain reaction...
Calcitonin gene-related peptide (CGRP), the predominant neurotransmitter in capsaicin-sensitive sensory nerves, is a potent vasodilator and inhibits proliferation of vascular smooth muscle cells. Previous investigations have demonstrated that hypotensive effect rutaecarpine (Rut) associated to stimulation CGRP synthesis release via activation vanilloid receptor subtype 1 (VR1) phenol-induced hypertensive rat. This study tested whether depressor inhibiting hypertrophy Rut mediated by...
To establish an electrochemical immunosensor for the determination of serum trypsin levels using a multiwall carbon nanotubes (MWCNTs)-composite-modified electrode.A MWCNT composite coated on surface bare gold electrodes was used fixation anti-trypsin antibody. The assembly process and performance indicators, including sensitivity, linear range detection, anti-jamming performance, stability, were examined by cyclic voltammetry (CV) impedance spectroscopy (EIS).With optimized experimental...
Pallister-Killian syndrome (PKS) is a rare sporadic genetic disorder usually caused by mosaicism of an extra isochromosome 12p (i(12p)). This retrospective study analysed the prenatal ultrasound manifestations and molecular cytogenetic results five PKS foetuses. Samples amniotic fluid and/or cord blood, skin biopsy placenta were collected. Conventional karyotyping single nucleotide polymorphism array (SNP array) performed on all or blood samples. Copy number variants sequencing (CNV-seq)...