A5076311860- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Hepatocellular Carcinoma Treatment and Prognosis
- Nutrition and Health in Aging
- Liver Diseases and Immunity
- Hepatitis C virus research
- Pancreatitis Pathology and Treatment
- Organ Transplantation Techniques and Outcomes
- Pediatric Hepatobiliary Diseases and Treatments
- COVID-19 Clinical Research Studies
- Systemic Lupus Erythematosus Research
- Hepatitis B Virus Studies
- Gallbladder and Bile Duct Disorders
- Frailty in Older Adults
- Drug-Induced Hepatotoxicity and Protection
- Pancreatic and Hepatic Oncology Research
- Long-Term Effects of COVID-19
- Renal Transplantation Outcomes and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Genetic and Kidney Cyst Diseases
- Colorectal Cancer Surgical Treatments
- Neurological Complications and Syndromes
- Genetics and Neurodevelopmental Disorders
- Digestive system and related health
- Lipoproteins and Cardiovascular Health
University of Alberta
2017-2025
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
2014-2024
University of Alberta Hospital
2018-2024
Alberta Hospital Edmonton
2018-2024
Hospital Angeles Pedregal
2024
Center for Digestive and Liver Diseases
2024
Hospital Español
2021
Foundation for Physical Medicine and Rehabilitation
2021
Universitat de Barcelona
2021
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2021
Baveno-VI guidelines recommend that patients with compensated cirrhosis liver stiffness by transient elastography (LSM-TE) <20 kPa and platelets >150,000/mm(3) do not need an esophagogastroduodenoscopy (EGD) to screen for varices, since the risk of having varices needing treatment (VNT) is <5%. It remains uncertain if this tool can be used in cholestatic diseases (ChLDs): primary biliary cholangitis (PBC) sclerosing (PSC). These may have a pre-sinusoidal component portal hypertension could...
Introduction and aim. Sarcopenia is an independent predictor of mortality in cirrhosis. Hypogonadism common cirrhosis has been associated with sarcopenia non-cirrhotic chronic liver disease populations. The aim this study to investigate if low testosterone levels patients Material methods. This a retrospective analysis prospectively collected data 211 cirrhotic undergoing evaluation for transplantation. was defined by computed tomography (CT) scan using specific cutoffs the 3rd lumbar...
Sarcopenia has been related to negative outcomes in different clinical scenarios from critical illness chronic conditions. The aim of this study was verify whether there an association between low skeletal muscle index and in-hospital mortality, intensive care unit admission, invasive mechanical ventilation need hospitalized patients with COVID-19.This a retrospective cohort referral center for COVID-19. We included all consecutive admitted the hospital February 26 May 15, 2020, confirmed...
Primary sclerosing cholangitis (PSC) may reoccur following liver transplantation (LT), and the diagnosis established once imaging studies demonstrate diagnostic cholangiographic appearance. To evaluate whether development of recurrent PSC (rPSC) is associated with cholestasis soon after LT, we studied changes in hepatic biochemistry within first 12 months were linked rPSC graft loss. We conducted a retrospective cohort analysis 158 transplant recipients Canada 549 from United Kingdom....
Hepatocellular carcinoma (HCC) constitutes the fourth leading cause of cancer-related mortality. Various factors, such as tumor size, multiplicity, and liver function, have been linked to prognosis HCC. The aim this study was explore prognostic significance muscle, subcutaneous visceral adipose tissue (VAT) mass, radiodensity, in a cohort 101 HCC patients treated with selective internal radiation therapy (SIRT). Muscle cross sectional area (cm2/m2) reported Hounsfield Unit (HU), were...
Criteria defined by the European Association for Study of Liver (EASL) and Imaging Reporting Data System (LI-RADS) enable hepatocellular carcinoma (HCC) diagnosis based on imaging in cirrhosis. Non-cirrhotic patients require biopsy given lower pre-test probability HCC. The objective our study was to assess performance EASL LI-RADS criteria HCC non-cirrhotic with chronic HBV infection.This a cross-sectional performed at referral center. We included all without cirrhosis focal liver lesions...
Cirrhosis is characterised by a prolonged asymptomatic period in which the inflammation persists, increasing as disease progresses. Characteristic of this increase pro-inflammatory cytokines and pro-oxidant molecules are determining factors development multiple organ dysfunction. In early cirrhosis, splanchnic arterial vasodilation, activation vasoconstrictor systems (renin-angiotensin-aldosterone) sympathetic nervous system (noradrenaline) bring about bacterial translocation systemic...
Abstract Background & Aims Information about the impact of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) in patients with liver cancer is lacking. This study characterizes outcomes and mortality risk this population. Methods Multicentre retrospective, cross‐sectional, international SARS‐CoV‐2 infection registered between February December 2020. Clinical data at diagnosis were registered. Results Two hundred fifty from 38 centres included, 218 hepatocellular carcinoma (HCC)...
Rett syndrome (RTT) is a neurodevelopmental disorder caused by mutations in the MECP2 gene, potentially disrupting lipid metabolism and leading to dyslipidemia (DLD) steatotic liver disease (SLD). Although SLD has been described RTT mouse models, it remains undocumented humans. We herein describe 24-year-old woman with who was evaluated for abnormal enzymes. Imaging revealed hepatic steatosis, transient elastography showed controlled attenuation parameter of 342 dB/m stiffness 7.1 kPa....
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a prevalent influenced by dietary factors. While high sugar and fat consumption are associated with weight gain, their specific impact on accumulation remains unclear. This study aimed to evaluate the relationship between saturated intake body composition. Methods: A cross-sectional was conducted from September 2021 February 2023 in workers tertiary care center Mexico City. Anthropometric measurements,...
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a prevalent influenced by dietary factors. While high sugar and fat consumption are associated with weight gain, their specific impact on accumulation remains unclear. This study aimed to evaluate the relationship between saturated intake body composition. Methods: A cross-sectional was conducted from September 2021 February 2023 in workers tertiary care center Mexico City. Anthropometric measurements,...
The most widely used staging system for hepatocellular carcinoma (HCC) is the Barcelona Liver Clinic Cancer (BCLC) system, which considers tumor burden, performance status, and liver function. Tumor burden assessed with cross sectional imaging of abdomen chest, controversy surrounds routine use bone scintigraphy (BS) detecting extrahepatic metastases. This study evaluated role BS in HCC Mexican patients.