A5100676629- MicroRNA in disease regulation
- Lung Cancer Diagnosis and Treatment
- Advanced Surface Polishing Techniques
- Advanced Machining and Optimization Techniques
- Pleural and Pulmonary Diseases
- Advanced machining processes and optimization
- RNA modifications and cancer
- Circular RNAs in diseases
- PARP inhibition in cancer therapy
- Tuberculosis Research and Epidemiology
- Liver Disease Diagnosis and Treatment
- RNA Interference and Gene Delivery
- Biomarkers in Disease Mechanisms
- Heavy Metal Exposure and Toxicity
- Diet, Metabolism, and Disease
- Toxin Mechanisms and Immunotoxins
- Cancer-related molecular mechanisms research
- Advancements in Transdermal Drug Delivery
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Alcohol Consumption and Health Effects
- Medical Imaging and Pathology Studies
- Congenital Diaphragmatic Hernia Studies
- Genetics and Neurodevelopmental Disorders
- High-Voltage Power Transmission Systems
- Chemotherapy-related skin toxicity
Meizhou City People's Hospital
2018-2025
Beijing Chest Hospital
2008-2024
Capital Medical University
2015-2024
Shandong University of Technology
2024
Longhua Hospital Shanghai University of Traditional Chinese Medicine
2024
Shanghai University of Traditional Chinese Medicine
2024
TianjinSino-German University of Applied Sciences
2024
Changchun University of Science and Technology
2023
Chinese Academy of Fishery Sciences
2023
Huizhou University
2012-2022
// Chengcao Sun 1, 2, * , Zhidong Liu 3, Shujun Li 4, Cuili Yang 1 Ruilin Xue Yongyong Xi Liang Wang Suqing Qiqiang He Jie Huang 5 Songping Xie Wenyang Jiang Dejia Department of Occupational and Environmental Health, School Public Wuhan University, 430071, P. R. China 2 Institute Global 3 Thoracic Surgery, Beijing Chest Hospital, Capital Medical 101149, P.R. 4 Hospital for the Prevention Treatment Diseases, People's 430000, These authors have contributed equally to this work Correspondence...
The purpose of this study was to figure out the effect ciRS-7/miR-7/NF-κB axis on development non-small cell lung cancer (NSCLC). In response, expressions ciRS-7, miR-7 and NF-κB subunit (ie RELA) within NSCLC tissues lines were determined with real-time polymerase chain reaction (RT-PCR) Western blot. Moreover, cells transfected pcDNA3-ciRS-7-ir, pcDNA3-ciRS-7, miR-NC mimic. Furthermore, targeted relationships between ciRS-7 miR-7, as well RELA, confirmed by luciferase reporter assay....
Next-generation sequencing (NGS) is an efficient and sensitive method to detect mutations from ctDNA. Many features clinical conditions could significantly affect the concordance between ctDNA corresponding tumor tissues. Our goal was systematically investigate critical factors contributing different tissues.We recruited two groups of IIIB or IV lung cancer patients: The standard group evaluate accuracy our tissues, study with various conditions. We applied unique identification (UID)...
9005 Background: ADJUVANT-CTONG1104, a randomized phase 3 trial showed adjuvant gefitinib treatment significantly improved disease-free survival (DFS) vs standard doublet chemotherapy in patients (pts) with epidermal growth factor receptor ( EGFR) mutation-positive resected stage II-IIIA (N1-N2) non-small-cell lung cancer (NSCLC). 5-year rate of N1N2 were 38%-50% IASLC staging system. Here, we present the final overall (OS) results from study. Methods: From Sep 2011 to April 2014, 222...
This paper presents a floating-buck dimmable LED driver for solid-state lighting applications. In the proposed driver, an adaptive timing difference compensation (ATDC) is developed to adaptively adjust off-time of low-side power switch enable achieve high accuracy average current over wide range input voltages and number output loads, fast settling time, operation frequency. The efficiency benefits from capabilities using synchronous rectifier having no sensing resistor in stage....
Antarctic krill (Euphausia superba), a shrimp-like marine crustacean, has become beneficial source of high-quality animal protein. Meanwhile, special focus been placed on its potential sensitization issue. In this study, 35 kDa protein was purified and identified to be tropomyosin (AkTM) by high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). The TM showed strong IgE-binding capacity shrimp/crab-allergic patients' sera, indicating that is the primary allergen in...
MicroRNs (miRNAs) are small non-coding RNAs that modulate the expression of protein-coding genes at post-transcription level and their dysregulated has been implicated in cardiovascular diseases. Circulating miRNAs have widely recommended as potential biomarkers for many diseases including coronary artery disease. In this study, miRNA profiles 6 normal (NCA), 12 patients with disease unstable angina (UA) ST-segment elevation myocardial infarction (STEMI) were determined by RNA sequencing....
Abstract Bacterial persisters, usually slow-growing, non-replicating cells highly tolerant to antibiotics, play a crucial role contributing the recalcitrance of chronic infections and treatment failure. Understanding molecular mechanism persister formation maintenance would obviously inspire discovery new antibiotics. The significant upregulation Mycobacterium tuberculosis Rv3290c, conserved mycobacterial lysine ε-aminotransferase (LAT) during hypoxia persistent model, suggested LAT in...
CANT1, calcium-activated nucleotidase 1, was reported to be upregulated in certain tumors. However, the function mechanism of CANT1 pan-cancer is still unclear.
To compare video-assisted thoracoscopic surgery (VATS) lobectomy and conventional open in patients with pulmonary tuberculosis (TB) who require surgery.Forty TB required were randomized to receive either VATS or lobectomy. Patient demographic, function, operative, postoperative data compared between the groups.There 20 received (median age 31.5 years, range 19-67 years) that 33.5 16-60 years). The two groups similar respect gender, function (all, P>0.05). Lobectomy was completed by 19 of...
Abstract Background To monitor dypsnea and mortality at 5 10 years, respectively, after surgical treatment of tuberculosis-destroyed lung (TDL) patients. Methods TDL patients treated surgically Beijing Chest Hospital from November 2007 to June 2019 were monitored in this observational study. Follow-up assessments respiratory function indicators survival conducted years post-surgery led patient grouping based on mMRC score into a dyspnea group (mMRC ≥ 1) non-dyspnea = 0). Cox regression...
Electro-phonophoresis (EP) has been used in various clinical fields. The objective of present study is to evaluate the skin permeability isoniazid (INH) and rifampicin (RIF) patients with tuberculous lymphadenitis aid EP validate applications this transdermal delivery system for treatment superficial extrapulmonary tuberculosis. INH RIF solutions were delivered transdermally, or without EP, surrounding tissue lesion 0.5 h. Local pyogenic fluids necrotic samples from infection sites collected...
The upstream regulators of microRNAs were rarely reported. Hydroquinone (HQ) is the main metabolite benzene, one important environmental factors contributing to leukemia and lymphoma. In HQ-induced malignant transformed TK6 (TK6-HT) cells, expression PARP-1 miR-223 upregulated. When in silencing TK6-HT was downregulated apoptotic cell number correspondingly increased. cells treated with HQ for different terms, dynamically observed found be decreased increased, respectively. Trichostatin A...
Electro-phonophoresis (EP) has been used as a drug delivery approach in clinical fields. The objective of the present study is to evaluate skin permeability isoniazid and rifampin guinea pigs by EP provide reference basis for applications such transdermal system treatment patients with superficial tuberculosis. Isoniazid solutions were delivered transdermally or without health 0.5 h. Local blood samples collected serially at 0, 1/2, 1, 2, 4, 6 24 h after dosing. Drug concentrations local...
ObjectiveThe sequence of vessel ligation in lobectomy can significantly affect the hematogenous spread circulating tumor cells (CTCs). Vein-first substantially reduces CTC dissemination and achieves favorable survival compared with artery-first ligation. In this study, we further explored whether timing pulmonary vein (PV) determined according to early late PV technique is associated dissemination.MethodsA total 44 patients who underwent uniform 2-port video-assisted thoracoscopic surgery...
Chest wall tuberculosis (TB) is an endemic disease with a large number of variants. The condition affects numerous parts the body and can penetrate skin to form chronic open ulcers. Current treatment methods include oral anti‑TB drugs surgery. However, conventional drug treatments are not effective due difficulty in achieving local concentration, certain patients unable tolerate recurrence rate for chest TB high following surgery, may result prolonged healing wounds patients, as well...
In view of the impact and influence grid-connected distributed energy on power system, this paper studies capacity optimization microgrid. First all, introduces non-cooperative game theory to build a model microgrid based game. Then, whale algorithm is used configure each player. Finally, using historical data certain region for analysis, results show that compared with single stakeholder method, photovoltaic station storage system revenue increased by 9% 2.5%, respectively.