A5102912394- Glaucoma and retinal disorders
- Retinal Imaging and Analysis
- Retinal Diseases and Treatments
- Retinal and Optic Conditions
- Corneal surgery and disorders
- Intraocular Surgery and Lenses
- Ophthalmology and Eye Disorders
- Artificial Intelligence in Healthcare and Education
- Retinal Development and Disorders
- Diversity and Career in Medicine
- Ophthalmology and Visual Health Research
- Corneal Surgery and Treatments
- Ocular Surface and Contact Lens
- Optical Coherence Tomography Applications
- Cardiovascular Health and Disease Prevention
- Neurological Disorders and Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Retinal and Macular Surgery
- Ocular Infections and Treatments
- Privacy-Preserving Technologies in Data
- Radiology practices and education
- Dental Education, Practice, Research
- Cerebral Venous Sinus Thrombosis
- Global Health Workforce Issues
- Redox biology and oxidative stress
Penn Presbyterian Medical Center
2023-2025
University of Pennsylvania
2023-2025
Technologies pour la Santé
2023-2025
New York University
2020-2024
Hinge Health
2024
NYU Langone Health
2019-2023
Columbia University Irving Medical Center
2009-2022
Columbia University
2010-2022
Ophthalmology Associates (United States)
1999-2022
New York Hospital Queens
2022
Recent evidence supports the presence of macular damage (within 8° central field) to retinal ganglion cells and associated visual field (VF) defects in glaucoma, even early stages. Despite this, our knowledge, association 10-2 VF with vision-related quality life (QOL) has not been well studied.To determine between QOL function as measured by 24-2 VFs patients primary open-angle glaucoma test hypothesis that disproportionate their status may exhibit overlooked test.In this cross-sectional...
Although almost equal numbers of male and female medical students enter into ophthalmology residency programs, whether they have similar surgical experiences during training is unclear.To determine differences for cataract surgery total procedural volume between residents residency.This retrospective, longitudinal analysis resident case logs from 24 US programs spanned July 2005 to June 2017. A 1271 were included. Data analyzed August 12, 2017, through April 4, 2018.Variables included mean...
Purpose: To assess the agreement between structural (optical coherence tomography [OCT]) and functional (visual field [VF]) glaucomatous damage with an automated method deviation/probability maps, to compare this a metric method. Methods: Wide-field spectral-domain OCT scans, including disc macula, 24-2 10-2 VFs were obtained from 45 healthy control (H) eyes/individuals, 53 eyes/patients mean deviation (MD) better than −6 dB diagnosed as "definite glaucoma" (DG) by experts. Abnormal...
Ocular hypertension is an important risk factor for the development of primary open-angle glaucoma (POAG). Data from long-term follow-up can be used to inform management patients with ocular hypertension.
Diagnosis and detection of progression glaucoma remains challenging. Artificial intelligence-based tools have the potential to improve standardize assessment but development these algorithms is difficult given multimodal variable nature diagnosis. Currently, most are focused on a single imaging modality, specifically screening diagnosis based fundus photos or optical coherence tomography images. Use anterior segment goniophotographs limited. The majority designed for disease prediction...
Purpose: To investigate the ocular surface microbiome of patients with unilateral or asymmetric glaucoma being treated topical ophthalmic medications in one eye and to determine whether microbial community changes were related measures disease. Methods: V3-V4 16S rRNA sequencing was conducted on swabs collected from both eyes 17 subjects: 10 asymmetric/unilateral using therapy only seven age-matched, healthy controls no history disease eyedrop use. Samples categorized into three groups:...
Glaucoma-related molecular biomarkers can improve clinical testing to diagnose the disease early, predict its prognosis, and monitor treatment responses. Based on evidence of increased oxidative stress in glaucomatous tissues, this study analyzed stress-related biomarker candidates blood aqueous humor samples with or without glaucoma.The collected from carefully selected groups 96 patients glaucoma 64 healthy subjects were included study. The for protein carbonyls advanced glycation end...
The Tube vs Trabeculectomy Trial (TVT) found that the 350-mm2 Baerveldt implant (tube) and trabeculectomy with mitomycin may be similarly effective in lowering intraocular pressure primary open-angle glaucoma. However, to date, there are no published long-term clinical data on cost-effectiveness of tube insertion.To assess these procedures compared maximal medical treatment.We used Markov cohort model a 5-year time horizon study hypothetical 100 000 patients who required glaucoma...
Purpose: Besides glia-driven neuroinflammation, growing evidence from analysis of human blood samples, isolated autoantibodies, and postmortem tissues also support systemic immune responses during neurodegeneration in glaucoma patients. To explore the T-cell–mediated component immunity, this study analyzed T lymphocytes patients' blood. Methods: Blood samples were collected 32 patients with 21 nonglaucomatous controls, mononuclear cells by Histopaque density gradient centrifugation. T-cell...
Pegasus outperformed 5 of the 6 ophthalmologists in terms diagnostic performance, and there was no statistically significant difference between deep learning system "best case" consensus ophthalmologists. The agreement gold standard 0.715, whereas highest ophthalmologist with 0.613. Furthermore, high sensitivity makes it a valuable tool for screening patients glaucomatous optic neuropathy.The purpose this study to evaluate performance identification neuropathy.Six system, Pegasus, graded 110...
<h3>Importance</h3> Little is known about the association between structural macular damage and self-reported visual function of people with glaucoma. <h3>Objective</h3> To determine vision-related quality life among patients primary open-angle glaucoma retinal ganglion cell plus inner plexiform layer (RGC+IPL) loss identified by spectral-domain optical coherence tomography (SD-OCT) machine-generated deviation maps thickness measurements. <h3>Design, Setting, Participants</h3> This...
TopicThis scoping review summarizes AI reporting in ophthalmology literature, respect to model development and validation. We characterize the state of transparency studies prospectively validating models for disease classification.Clinical RelevanceUnderstanding what elements authors currently describe regarding their may aid future standardization reporting. This highlights need facilitate critical appraisal prior clinical implementation, minimize bias inappropriate use. Transparent can...