A5015183244- Antibiotic Resistance in Bacteria
- Mosquito-borne diseases and control
- Malaria Research and Control
- Tuberculosis Research and Epidemiology
- Antimicrobial Resistance in Staphylococcus
- Antibiotic Use and Resistance
- Viral Infections and Vectors
- Pneumonia and Respiratory Infections
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Bacterial biofilms and quorum sensing
- Mycobacterium research and diagnosis
- Urinary Tract Infections Management
- Pneumocystis jirovecii pneumonia detection and treatment
- Advanced Topics in Algebra
- Bacterial Identification and Susceptibility Testing
- Pharmaceutical and Antibiotic Environmental Impacts
- Bacterial Infections and Vaccines
- HIV, Drug Use, Sexual Risk
- Antibiotics Pharmacokinetics and Efficacy
- Blood donation and transfusion practices
- HIV/AIDS Research and Interventions
- Algebraic structures and combinatorial models
- Vibrio bacteria research studies
- Rice Cultivation and Yield Improvement
Tribhuvan University
2016-2025
Kathmandu University
2025
B.P. Koirala Institute of Health Sciences
2008-2024
Louisiana State University of Alexandria
2018-2024
Universal College of Medical Sciences
2024
Instituut voor Tropische Geneeskunde
2024
Universidad Nacional de Córdoba
2024
Beltsville Agricultural Research Center
2024
Agricultural Research Service
2024
College of Medical Sciences
2024
Abstract Background Dengue is one of the newest emerging diseases in Nepal with increasing burden and geographic spread over years. The main objective this study was to explore epidemiological patterns dengue since its first outbreak (2006) 2019 Nepal. Methods This a retrospective analysis that covers last 14 years (2006–2019) reported cases from Epidemiology Diseases Control Division (EDCD), Ministry Health Population, Government . Reported were plotted time maps case incidence generated...
Introduction: Resistance to carbapenem in Gram-negative bacteria is attributable their ability produce carbapenemase enzymes. The main objective of this study was detect the presence blaOXA-48 genes carbapenem-resistant uropathogenic Escherichia coli and Klebsiella pneumoniae isolated from urine samples patients attending Alka Hospital, Jawalakhel, Lalitpur, Nepal. Methods: A total 1013 mid-stream were collected with suspected urinary tract infection (UTI) between April September 2018....
The goal to eliminate malaria from the Asia-Pacific by 2030 will require safe and widespread delivery of effective radical cure malaria. In October 2017, Asia Pacific Malaria Elimination Network Vivax Working Group met discuss impediments primaquine (PQ) cure, how these can be overcome methodological difficulties in assessing clinical effectiveness cure. salient discussions this meeting which involved 110 representatives 18 partner countries 21 institutional organizations are reported....
Emergence and spread of antimicrobial resistance (AMR) is a global threat significantly affects the treatment options for common infectious diseases. Inappropriate use antibiotics, particularly third-generation cephalosporins, has contributed to development AMR. This study aims determine prevalence extended-spectrum β-lactamase (ESBL) production in Escherichia coli Klebsiella species isolated from various clinical samples.This cross-sectional was conducted at International Friendship...
Pakistan is facing a severe energy crisis due to its heavy dependency on the import of costly fossil fuels, which ultimately leads expansive electricity generation, low power supply, and interruptive load shedding. In this regard, utilization available renewable resources within country for production can lessen crisis. Livestock waste/manure considered most abundant material biogas generation. primarily an agricultural country, livestock widely kept by farming community, in order meet their...
Abstract Background Microscopic examination of Giemsa-stained blood films remains the reference standard for malaria parasite detection and quantification, but is undermined by difficulties in ensuring high-quality manual reading inter-reader reliability. Automated quantification may address this issue. Methods A multi-centre, observational study was conducted during 2018 2019 at 11 sites to assess performance EasyScan Go, a microscopy device employing machine-learning-based image analysis....
The largest dengue outbreak in the history of Nepal occurred 2022, with a significant number casualties. It affected all 77 districts, nation's capital, Kathmandu (altitude 1300 m), being hardest hit. However, molecular epidemiology this outbreak, including virus (DENV) serotype(s) responsible for epidemic, remain unknown. Here, we report epidemic trends, clinico-laboratory features, and serotypes their viral load profiles that are associated Nepal. Dengue-suspected febrile patients were...
Screening of transfusion-transmissible infections (TTIs) among blood donors can be a cost-effective approach to monitor the prevalence, distribution, and trends healthy-looking individuals. The study aimed determine seroprevalence four TTIs, human immunodeficiency virus (HIV), hepatitis B (HBV), C (HCV) syphilis, in Kathmandu, Nepal.A total 21,716 units were tested for presence anti-HIV 1/2 IgG/IgM, HBsAg, anti-HCV anti-Treponema pallidum IgG/IgM/IgA using commercial ELISA kits following...
In recent years, the use of unmanned aerial vehicles (UAVs) has received increasing attention in remote sensing, vegetation monitoring, index (VI) mapping, precision agriculture, etc. It many advantages, such as high spatial resolution, instant information acquisition, convenient operation, maneuverability, freedom from cloud interference, and low cost. Nowadays, different types UAV-based multispectral minisensors are used to obtain either surface reflectance or digital number (DN) values....
Abstract Background Plasmid-mediated resistance to the last-resort drugs: carbapenems and colistin is an emerging public health threat. The studies on prevalence co-expression of resistant genes among livestock human pathogens are rare in Nepal. This first study Nepal exploring co-existence gene, mcr -1 along with carbapenemase OXA -48 Escherichia coli isolated from poultry clinical specimens. Methods A total 240 rectal swabs chickens five different farms Kathmandu valley 705 mid-stream...
Abstract Nepal suffers from high burden of antimicrobial resistance (AMR) due to inappropriate use antibiotics. The main objective this study was explore knowledge, attitude and practices antibiotics uses among patients, healthcare workers, laboratories, drug sellers farmers in eight districts Nepal. A cross-sectional survey conducted between April July 2017. total 516 individuals participated a face-to-face interview that included clinicians, private dispensers, public health...
The prevalence of antimicrobial resistance (AMR) among Gram-negative bacteria is alarmingly high. Reintroduction colistin as last resort treatment in the infections caused by drug-resistant has led to emergence and spread resistance. This study was designed determine drug-resistance beta-lactamase-producing strains Escherichia coli Klebsiella pneumoniae, isolated from clinical specimens received at a tertiary care centre Kathmandu, Nepal during period March August, 2019.A total 3216...
We sequenced Leishmania donovani genomes in blood samples collected emerging foci of visceral leishmaniasis western Nepal. detected lineages very different from the preelimination main parasite population, including a new lineage and rare one previously reported eastern Our findings underscore need for genomic surveillance.
Japanese encephalitis (JE) is endemic in the Terai region of Nepal. There little information on occurrence JE outside and particularly densely populated Kathmandu valley. Acute syndrome (AES) cases were detected using a sentinel surveillance system that has been functioning since 2004. was confirmed anti-JE IgM ELISA. All laboratory-confirmed occurred valley during 2006 followed up for verification residence travel history. 40 residents valley, including 30 had no history incubation period....
We report on the changing epidemiology of two important flaviviruses in Nepal: Japanese encephalitis (JE) and dengue viruses. Morbidity mortality Nepal is thousands since JE was introduced 1978. launched an extensive laboratory-based surveillance 2004. experienced a remarkable reduction disease burden after mass immunizations from 2005 to 2010, when 2,040 infections 205 JE-related deaths were confirmed. With its emergence 2006, has become significant challenge country, highlighted by sudden...
Dengue virus (DENV) is expanding toward previously nonendemic areas. DENV has recently been introduced in Nepal with limited information. We report the clinical features and serotype distribution of during 2010 outbreaks. A total 1,215 dengue cases at two major hospitals central western were investigated. Demographic, clinical, laboratory parameters recorded. Serum specimens tested for by IgM/IgG enzyme-linked immunosorbent assays (ELISAs) reverse transcription polymerase chain reaction...
In recent years, the use of image fusion method has received increasing attention in remote sensing, vegetation cover changes, indices (VIs) mapping, etc. For making high-resolution and good quality (with low-cost) VI mapping from a fused image, its underlying factors need to be identified properly. example, same-sensor generally higher spatial resolution ratio (SRR) (1:3 1:5) but multi-sensor lower SRR (1:8 1:10). addition SRR, there might other affecting index (FVI) result which have not...