A5062710421- Intensive Care Unit Cognitive Disorders
- Family and Patient Care in Intensive Care Units
- Respiratory Support and Mechanisms
- Hemodynamic Monitoring and Therapy
- Palliative Care and End-of-Life Issues
- Sepsis Diagnosis and Treatment
- Cardiac Arrest and Resuscitation
- Cardiac, Anesthesia and Surgical Outcomes
- Healthcare Regulation
- Patient Safety and Medication Errors
- Blood transfusion and management
- Parasites and Host Interactions
- Healthcare professionals’ stress and burnout
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Ultrasound in Clinical Applications
- Health Systems, Economic Evaluations, Quality of Life
- Emergency and Acute Care Studies
- Grief, Bereavement, and Mental Health
- COVID-19 and healthcare impacts
- COVID-19 Clinical Research Studies
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Long-Term Effects of COVID-19
- Family Caregiving in Mental Illness
- Muscle and Compartmental Disorders
- Electrolyte and hormonal disorders
Hospital Israelita Albert Einstein
2017-2025
Hospital São Paulo
2005-2023
Insper
2022
Universidade de São Paulo
2014-2017
Instituto do Coração
2017
Hospital Sírio-Libanês
2005-2015
Universidade Federal de São Paulo
2013
Latin American Sepsis Institute
2013
Harvard University
2001-2008
Massachusetts General Hospital
2001-2008
than 5 ml/kg PBW, mean EFFi increased from 0.722 to 0.736, or by 1.8 6 0.8% (mean SD).The exact value chosen for VANA appears not be critical.Therefore, a moderate error in flow sensor calibration is of low importance.In future studies, should compared with alternative parameters (e.g., VAE/VT proposed Lucangelo and colleagues [10]).Because VDphys/VT reflect uneven V : /Q among lung compartments, it was expected that they correlate closely.EFFi easier study, as noninvasive may continuously...
Abstract Introduction Contemporary information on mechanical ventilation (MV) use in emerging countries is limited. Moreover, most epidemiological studies ventilatory support were carried out before significant developments, such as lung protective or broader application of non-invasive (NIV). We aimed to evaluate the clinical characteristics, outcomes and risk factors for hospital mortality failure NIV patients requiring Brazilian intensive care units (ICU). Methods In a multicenter,...
Background: Noninvasive positive-pressure ventilation (NPPV) has been shown to be effective in select patients enrolled clinical trials. However, few data are available on the use of NPPV as routine standard medical care for with respiratory failure outside controlled Measurements and Main Results: All receiving a 1-yr period acute or chronic who did not do intubate/resuscitate status were evaluated. Demographic, physiological, laboratory collected long was provided. Data recorded 449...
Introduction Patients and family members undergo different experiences of suffering from emotional disorders during ICU stay after discharge. The purpose this study was to compare the incidence anxiety, depression post-traumatic stress disorder (PTSD) symptoms in pairs (patient respective member), at an open visit 30 90-days post-ICU We hypothesized that there a positive correlation with severity among patterns over time. Methods A prospective conducted 22-bed adult general including...
Readmission to the intensive care unit (ICU) is associated with poor clinical outcomes, increased length of ICU and hospital stay, higher costs. Nevertheless, knowledge epidemiology readmissions, risk factors, attributable outcomes restricted developed countries.To determine effect readmissions on in-hospital mortality, incidence identify predictors compare resource use between readmitted nonreadmitted patients in a developing country.This retrospective single-center cohort study was...
An intensive care unit (ICU) admission is a stressful event for the patient and patient's family. Several studies demonstrated symptoms of anxiety, depression, posttraumatic stress disorder in family members patients admitted to ICU. Some recognize that open visitation policy (OVP) related reduction anxiety depression an improvement satisfaction. However, some issues have been presented as barriers adoption strategy. This study was designed evaluate perceptions physicians, nurses,...
Importance Despite its implementation in several countries, there has not been a randomized clinical trial to assess whether telemedicine intensive care units (ICUs) could improve outcomes of critically ill patients. Objective To determine an intervention comprising daily multidisciplinary rounds and monthly audit feedback meetings performed by remote board-certified intensivist reduces ICU length stay (LOS) compared with usual care. Design, Setting, Participants A parallel cluster baseline...
BackgroundGeoeconomic variations in epidemiology, the practice of ventilation, and outcome invasively ventilated intensive care unit (ICU) patients without acute respiratory distress syndrome (ARDS) remain unexplored. In this analysis we aim to address these gaps using individual patient data four large observational studies.MethodsIn pooled harmonised from ERICC, LUNG SAFE, PRoVENT, PRoVENT-iMiC prospective studies, which were conducted June, 2011, December, 2018, 534 ICUs 54 countries. We...
This retrospective multicenter cohort study compared characteristics and outcomes of 5,790 critically ill patients with COVID-19 in Brazil's public private intensive care units. Patients units exhibited greater disease severity, more frequent use organ support, higher mortality rates to those The risk in-hospital death was than twice as high ■ Public unit presented comorbidities severity at admission. required invasive support (e.g., mechanical ventilation, vasopressors, renal replacement...
Field hospitals, following the Fangcang Shelter Hospital model, were critical during global COVID-19 pandemic to alleviate strain on overwhelmed healthcare systems. Despite their widespread adoption, concerns persist regarding efficacy and cost-effectiveness. This study aimed assess impact of Pacaembu in São Paulo, Brazil pandemic, specifically focusing lives saved associated public health costs. retrospective cohort was conducted April 6 June 29. The 200-bed field hospital, a collaboration...
To evaluate whether a strategy of double-dose influenza vaccination during hospitalization for an acute coronary syndrome (ACS) compared with standard-dose outpatient (as recommended by current guidelines) would further reduce the risk major cardiopulmonary events.Vaccination against Influenza to Prevent cardiovascular events after Acute Coronary Syndromes (VIP-ACS) was pragmatic, randomized, multicentre, active-comparator, open-label trial blinded outcome adjudication comparing two...
To identify the independent variables associated with death within 4 days after first sepsis-induced organ dysfunction.In this prospective observational study, severe sepsis and septic shock patients were classified into 3 groups: Group 1, survivors; 2, late non-survivors; 3, early non-survivors. Early was defined as occurring dysfunction. Demographic, clinical laboratory data collected submitted to univariate multinomial analyses.The study included 414 patients: 218 (52.7%) in 165 (39.8%)...
A previous volume history should be established prior to pressure– (P–V) curve measurement, however the effect of and peak inspiratory pressure (PIP) during P–V measurement has not been explored. Lung injury was created by lavage in nine sheep (25–35 kg). After stabilization, four curves were sequentially obtained with PIP 40, 50, 60, 40 cm H2O. Prior each delivered for 1 min same as measurement. We compared lower inflection point (Pflex), upper (UIP), compliance below Pflex (Cstart),...
Prolonged invasive mechanical ventilation and reintubation are associated with adverse outcomes increased mortality. Daily screening to identify patients able breathe without support is recommended reduce the length of ventilation. Noninvasive positive-pressure has been proposed as a technique shorten time that remain on ventilation.We conducted before-and-after study evaluate efficacy an intervention combined daily use noninvasive immediately after extubation in selected patients. The...
To evaluate the satisfaction of intensive care unit staff with a computerized physician order entry and to compare concept relevance among healthcare workers.We performed cross-sectional survey assess in 30-bed medical/surgical adult using self-administered questionnaire. The questions used for grading levels were answered according numerical scale that ranged from 1 point (low satisfaction) 10 points (high satisfaction).The majority respondents (n=250) female (66%) between ages 30 35 years...
The pathophysiological mechanisms associated with the effects of red blood cell (RBC) transfusion on cardiopulmonary function and inflammation are unclear. We developed an experimental model homologous 14-days stored RBC in hypovolemic swine to evaluate short-term system inflammation. Sixteen healthy male anesthetized (68±3.3 kg) were submitted controlled hemorrhage (25% volume). Two units non-filtered from each animal under bank conditions for 14 days. After 30 min hypovolemia, control...
To develop experimental models of erythrocyte transfusion, the first step is to ensure viability red blood cells transfused. In this pilot study, we assessed transfused with validation in vitro and vivo homologous swine erythrocytes stored for 14 days.Blood collected from one Agroceres was two cell units. performed by labeling Na₂⁵¹CrO₄ recovering viable after 24 hours infusion autologous four animals. at baseline days sixteen units measuring hemoglobin, hematocrit, hemolysis index free...
To evaluate outcomes of vascular surgeries and identify strategies to improve public care.This was a descriptive, qualitative, cross-sectional survey involving 30 specialists the Hospital Israelita Albert Einstein via Zoom. The procedures performed in Public Health System extracted through Big Data analysis were discussed, 53 potential care care.There consensus on mandatory reporting some key complications after complex arterial surgeries, such as stroke carotid revascularization amputations...