A5086211005- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Coronary Interventions and Diagnostics
- Blood Pressure and Hypertension Studies
- Cardiac pacing and defibrillation studies
- Cardiac Structural Anomalies and Repair
- Cardiovascular Health and Disease Prevention
- Atrial Fibrillation Management and Outcomes
- Acute Myocardial Infarction Research
- Cardiac electrophysiology and arrhythmias
- Cardiomyopathy and Myosin Studies
- Venous Thromboembolism Diagnosis and Management
- Cardiac Arrhythmias and Treatments
- Ultrasound and Hyperthermia Applications
- Heart Rate Variability and Autonomic Control
- Cardiovascular Effects of Exercise
- Coronary Artery Anomalies
- Advanced MRI Techniques and Applications
- Antiplatelet Therapy and Cardiovascular Diseases
- ECG Monitoring and Analysis
- Medical Imaging Techniques and Applications
- Inflammatory Biomarkers in Disease Prognosis
- Cardiac tumors and thrombi
- Kawasaki Disease and Coronary Complications
Inha University
2010-2022
Inha University Hospital
2013-2022
Weatherford College
2020
National Institutes of Health
2018
Chungnam National University Hospital
2016
Cleveland Clinic
2003-2010
Cleveland Foundation
2005
Imaging Center
2003
Asan Medical Center
2000
University of Ulsan
2000
This study was conducted to elucidate the geometric differences of mitral apparatus in patients with significant regurgitation caused by ischemic cardiomyopathy (ICM-MR) and idiopathic dilated (DCM-MR) use real-time 3D echocardiography (RT3DE).Twenty-six ICM-MR posterior infarction, 18 DCM-MR, 8 control subjects were studied. With software, commissure-commissure plane 3 perpendicular anteroposterior (AP) planes generated for imaging medial, central, lateral sides valve (MV) during mid...
Recent studies suggest that the intracoronary administration of bone marrow (BM)-derived mesenchymal stem cells (MSCs) may improve left ventricular function in patients with acute myocardial infarction (AMI).However, there is still argumentative for safety and efficacy MSCs AMI setting.We thus performed a randomized pilot study to investigate AMI.Eighty after successful reperfusion therapy were randomly assigned received an autologous BM-derived into infarct related artery at 1 month.During...
PurposeCombination therapy with ezetimibe and statins is recommended in cases of statin intolerance or insufficiency. The objective this study was to compare the efficacy safety combination rosuvastatin versus those monotherapy patients hypercholesterolemia.MethodsI-ROSETTE (Ildong ROSuvastatin & ezETimibe for hypercholesTElolemia) an 8-week, double-blind, multicenter, Phase III randomized controlled trial conducted at 20 hospitals Republic Korea. Patients hypercholesterolemia who required...
Atrial fibrillation (AF) can be a risk factor for development of significant tricuspid regurgitation (TR). We investigated which clinical and echocardiographic parameters were related to severity functional TR in patients with lone AF. A total 89 AF enrolled (75 ± 11 years; 48% male): 13 severe TR, 36 moderate 40 consecutive less than mild TR. Clinical measurements including right ventricular (RV) remodeling function evaluated. Patients more older had frequently persistent (each p < 0.001)....
Ticagrelor has shown greater, more rapid and consistent platelet inhibition than clopidogrel. However, the superiority of ticagrelor for preventing ischaemic damage in STEMI patients not been proven. The aim this trial was to assess whether is superior clopidogrel microvascular injury ST-elevation myocardial infarction (STEMI).Patients with underwent prospective random assignment receive a loading dose (LD) 600 mg or 180 (1:1 ratio) before primary percutaneous coronary intervention (PCI). As...
Clinical practice guidelines have been slowly and inconsistently applied in clinical practice, certain evidence-based, guideline-driven therapies for heart failure (HF) significantly underused. The purpose of this study was to survey guideline compliance its effect on outcomes the treatment systolic HF Korea.The SUrvey Guideline Adherence Treatment Systolic Heart Failure Real World (SUGAR) trial a multi-center, retrospective, observational subjects with (ejection fraction <45%) admitted 23...
This study was done to explore the 3D geometry of normal tricuspid annulus and compare it with mitral (MA), using real-time echocardiography (RT3DE) newly developed computer software.Thirteen left ventricular (LV) 13 right (RV) volumetric images were obtained RT3DE from subjects. LV RV data segmented into 16 rotational apical planes (angle increment=11.25 degrees ) around axis apex through center two annuli, software (TomTec, Co., Munich, Germany). Two hinge points MA TA traced in each plane...
Objective: Most studies of the pathogenesis functional mitral regurgitation (MR) have focused on alterations in ventricular function and geometry. We used a novel 3D echocardiographic method to assess abnormalities annular (MA) geometry motion patients with ischemic MR (IMR) compared these data those obtained from normal subjects caused by dilated cardiomyopathy (DMR). Methods: Real time echo was performed 12 subjects, 25 IMR, 14 DMR. Eight points along saddle‐shaped MA were identified using...
Objective: In patients with ischemic mitral regurgitation (IMR), we assessed dynamic changes in annular geometry and motion during the cardiac cycle, examined their association severity of IMR, using our computerized three‐dimensional (3D) echo method. Methods: Real‐time 3D was performed 12 normal controls 25 IMR. The saddle‐shaped annulus reconstructed every volume/frame a cycle. For each volume/frame, area (MAA) contraction that expressed as percentage largest MAA accounted for by change...
AimsThe geometry of the mitral apparatus changes dynamically throughout systole and diastole. We investigated how geometric dynamics could affect haemodynamics outflow tract in patients with hypertrophic cardiomyopathy presenting systolic anterior motion (HCMSAM) using three-dimensional (3D) echocardiography.
Three-dimensional (3D) speckle tracking echocardiography (STE) has been developed to overcome the limitations of two-dimensional (2D) STE and applied in several clinical settings. However, no data exist about prognostic value 3DSTE-based strain on outcome after myocardial infarction (MI). This study was designed investigate area (AS) by 3D predicting acute MI.We assessed 96 patients (62±14 years, 72% male) with MI who had undergone a coronary angiography. Clinical parameters conventional...
To validate the accuracy of mitral annular motion assessed by real-time three-dimensional echocardiography (RT3DE) as a surrogate for determination left ventricular function in comparison with magnetic resonance imaging (MRI).Forty-seven patients variety cardiac pathologies underwent both RT3DE and MRI exams. After 3D data sets were transferred to PC custom-made program, nine consecutive rotational apical plane images (20 degrees apart) displayed. The two leaflet insertion points manually...
We aimed to investigate whether thrombus aspiration could preserve the index of microcirculatory resistance (IMR) after primary percutaneous coronary intervention (PCI) in patients with ST-elevation myocardial infarction (STEMI).Sixty-three STEMI were randomised into two groups: PCI (aspiration group, n=33) and without (non-aspiration n=30). IMR was measured using a pressure-temperature sensor-tipped wire. Echocardiography performed at baseline six-month follow-up. No significant differences...
A pathophysiological mechanism of microvascular dysfunction in ST-segment elevation myocardial infarction (STEMI) is multifactorial; thus, multiple modalities were needed to precisely evaluate a microcirculation.We complementarily assessed microcirculation STEMI by the index microcirculatory resistance (IMR) and coronary flow reserve (CFR) immediately after primary percutaneous intervention 89 patients. Cardiovascular cerebrovascular events (MACCE) including cardiovascular death, target...
BACKGROUND The neutrophil-to-lymphocyte ratio (NLR) has been proven to be a reliable inflammatory marker. A recent study reported that elevated NLR is associated with adverse cardiovascular events in patients ST-segment elevation myocardial infarction (STEMI). We investigated whether at emergency room (ER) mechanical complications of STEMI undergoing primary percutaneous coronary intervention (PCI). METHODS total 744 who underwent successful PCI from 2009 2018 were enrolled this study. Total...
Significant mitral regurgitation (MR) is frequently associated with coronary artery disease. The precise geometric predictors of significant MR in ischemic cardiomyopathy are not clearly defined. We performed real-time 3D echocardiography (RT3DE) 48 patients scheduled for infarct exclusion surgery or Dor procedure, 22 whom had moderate severe (DorMR) and 26 no trivial (DorNoMR).Two orthogonal apical volumetric planes LV, commissure-commissure (CC) antero-posterior (AP) planes, were generated...
Purpose: A maximum P-wave duration (Pmax) of 110 msec and a dispersion (PWD) 40 are accepted indicators disturbance in interatrial conduction an inhomogeneous propagation the sinus impulse, respectively.The left atrial (LA) volume has been reported to be strongly associated with systolic diastolic dysfunction is considered index remodeling.We aimed investigate relationship between LA Pmax or PWD patients congestive heart failure (CHF).Patients Methods: Sixty-one CHF were enrolled this...
This study was conducted to explore the geometrical changes of mitral annulus during systole.The 3D shape reconstructed in 13 normal subjects who had structure apparatus using real-time echocardiography (RT3DE) and computer software.The two orthogonal (antero-posterior commissure-commissure) dimensions, areas (2D projected surface) non-planarity were estimated early, mid late systole.We demonstrated that MA a "saddle shape" appearance it consistently enlarged mainly antero-posterior...
Objective: The results from the ASCOT CAFÉ study demonstrated inferiority of beta blockers in reducing central aortic blood pressure. In this study, we wanted to demonstrate whether or not second-generation with higher 1 selectivity, namely bisoprolol, may counterbalance effect bradycardia through reduced reflection wave magnitude resulting relative lack increase peripheral vascular resistance. Method: This was a prospective, randomized, open-label, active-controlled trial 209 hypertensive...
We herein report the case of a 23-year-old man who presented with recurrent pancreatitis and was diagnosed primary pancreatic extranodal natural killer/T-cell lymphoma, nasal type, involving right ventricle. The cardiac involvement screened confirmed by transthoracic echocardiography (TTE), magnetic resonance imaging fluorodeoxyglucose positron emission tomography. Although patient did not have any symptoms or evidence arrhythmia before chemotherapy, he fatal newly developed ventricular...