Root colonization by a plant-beneficial rhizobacterium, Pseudomonas chlororaphis O6, induces disease resistance in tobacco against leaf pathogens Erwinia carotovora subsp. SCC1, causing soft-rot, and syringae pv. tabaci, wildfire. In order to identify the bacterial determinants involved induced systemic plant diseases, extracellular components produced bacterium were fractionated purified. Factors culture filtrate inducing retained aqueous fraction rather than being partitioned into ethyl...

Purpose Radiation-induced oral mucositis limits the delivery of high-dose radiation to head and neck cancer. This study investigated effectiveness epicatechin (EC), a component green tea extracts, on radiation-induced in vitro vivo. Experimental Design The effect EC cytotoxicity was analyzed human keratinocyte line HaCaT. apoptosis, change mitochondrial membrane potential (MMP), reactive oxygen species (ROS) generation changes signaling pathway were investigated. In vivo therapeutic effects...

CCL15, a member of the CC chemokine family, is potent chemoattractant for leukocytes and endothelial cells (ECs). Given that chemokines play key roles in vascular inflammation, we investigated effects hypoxia/reoxygenation (H/R) on expression human CCL15 role upregulating ICAM-1 ECs. We found exposure ECs to H/R increased ICAM-1, which resulted an increase monocyte adhesivity Further studies revealed knockdown or CCR1 attenuated after H/R, suggesting upregulated by CCL15. Stimulation with...

Lactoferrin (Lf) is known to have anti‐inflammatory activity, but the mechanisms of action by Lf remain be elucidated. Here, we demonstrated that TNF‐α‐induced expression intercellular adhesion molecule‐1 (ICAM‐1) was down‐regulated in a DNA‐binding dependent manner at transcriptional level endothelial cells. Our results showed bound DNA region ICAM‐1 promoter vitro as well chromatin context. inhibited binding NF‐κB proximal site promoter. This type repression represents an additional...

Radiation-induced oral mucositis is a dose-limiting toxic side effect for patients with head and neck cancer. Numerous attempts at improving radiation-induced have not produced qualified treatment. Ginseng polysaccharide has multiple immunoprotective effects. Our aim was to investigate the effectiveness of Korean red ginseng (KRG) on damage in human keratinocyte cell line HaCaT an vivo zebrafish model. Radiation inhibited proliferation migration viability assay wound healing assay,...

Cynanchum wilfordii has been traditionally used in eastern Asia for the treatment of various diseases such as gastrointestinal and arteriosclerosis. Cynandione A (CA), an acetophenone, is one major constituents from roots C. wilfordii. In present study, anti-inflammatory activities CA were investigated lipopolysaccharide (LPS)-treated RAW264.7 macrophages LPS-administered C57BL/6 N mice. significantly decreased LPS-induced production nitric oxide prostaglandin E2 a dose-dependent manner,...

Angiogenesis, the growth of new blood vessels from pre-existing vasculature, plays an important role in physiological and pathological processes such as embryonic development wound healing revascularization tissues after exposure to ischemia. We investigated effects jaceosidin, a main constituent medicinal herbs genus Artemisia, on angiogenesis signaling pathways endothelial cells. Jaceosidin stimulated proliferation, migration tubulogenesis ECs well ex vivo sprouting aorta rings, which are...

Previously developed Intradialytic hypotension (IDH) prediction models utilize clinical variables with potential privacy protection issues. We an IDH model using minimal variables, without the risk of infringement.Unidentifiable data from 63,640 hemodialysis sessions (26,746 79 patients for internal validation, 36,894 255 external validation) two Korean hospital databases were finally analyzed, three definitions: (1) systolic blood pressure (SBP) nadir <90 mmHg (Nadir90); (2) SBP decrease...

Radiation-induced normal cell damage limits the delivery of high-dose radiation to targeted cancer. This study investigated effect epicatechin (EC), a minor component green tea extracts, on radiation-induced cellular in vitro primary cultured human fibroblasts and vivo zebrafish model. Cell viability, proliferation wound-healing efficacy, mitochondrial membrane potential, reactive oxygen species (ROS) generation as well changes signaling pathway related apoptosis were fibroblasts. The...

Stewartia koreana (S. koreana) has been used in the treatment of inflammatory diseases, such as acute gastroenteritis and aches, Korean folk medicine reported to have a number biological activities, anti-inflammatory activity promotion angiogenesis. In this study, we aimed determine effects S. extract (SKE) its components on dermal fibroblast growth migration, investigate wound healing mice. vitro experiments revealed that numbers SKE-treated cells increased by approximately 2.5­‑ 3.7-fold...

Background Inflammation levels are lower in East Asians than Western people. We studied the association between high-sensitivity hs-CRP (C-reactive protein) and adverse outcomes Korean patients with chronic kidney disease. Methods Results included 2018 participants from KNOW-CKD (Korean Cohort Study for Outcome Patients With Chronic Kidney Disease) April 2011 February 2016. The primary outcome was a composite of extended major cardiovascular events (eMACE) or all-cause mortality. secondary...

Abstract Background The stabilizing effect of lavender and the arousal peppermint essential oils are acknowledged used widely in aromatherapy cosmetics industry. However, no evaluation method confirms effects through quantitative objective electroencephalogram (EEG) results; instead, only a psychological subjective exists. Therefore, this study aims to create new emotional cosmetic paradigm using EEG values. Moreover, it enables interpretation results addition survey outcomes. Methods For...

The spread of COVID-19 has made mask wear essential. Expecting that long-term would change the characteristics skin, this study investigated changes in skin wrinkles and pores caused by whether or not use moisturizers an effect on any changes.The participants were 20 women who instructed to a for at least 6 hours day 4 weeks. Measurements obtained before after weeks wear. effects application moisturizer assessed applying within mask-wearing area. They completed questionnaire about end...

The purpose of this randomized controlled trial was to compare outcomes limited open and short wrist transverse techniques in patients with carpal tunnel syndrome. In a single centre trial, 84 idiopathic syndrome were before surgery or release. evaluated at 6 weeks, 3 months, 1 2 years after surgery. At every follow-up, the Brigham Women’s Carpal Tunnel Questionnaire scores, scar discomfort, subjective patient satisfaction evaluated. Two surgery, five lost follow-up. groups had similar...

Focus on the hair and cuticle is increasing. The first layer to be exposed damage area of primary protection. For such reasons, product manufacturers consider protection important. However, previous studies used only visual assessment examine cuticle. This study aimed obtain changes in cuticles measure roughness using a HIROX microscope.A total 23 female subjects same products daily for 4 weeks. Three samples per subject were collected from three different areas head. Measurements taken...

Abstract Background COVID‐19 is a serious respiratory disease, and wearing masks has become essential in daily life. Nevertheless, the number of people complaining skin problems caused by increasing. Therefore, we investigated characteristics changes sensitive mask. Materials methods Twenty healthy Korean women with participated this study. To determine any skin‐related mask‐wearing, evaluated redness, hydration, transepidermal water loss (TEWL), moisture at 2.5 mm below surface before 4 h...

A Si-based coupled double dot has been studied for its application to two-qubit gate. The authors manipulated electron number of each by using adjacent side gate and finally observed a honeycomb charge-stability pattern, demonstrating interdot capacitive coupling. From the diagram capacitance-related coupling parameters were extracted. Moreover, fine structure in conductance trace near triple point honeycomb, where tunnel is maximized, was measured finite bias, dependence on attributed spin...

The scalp care market is growing rapidly and research into the factors associated with sensitive performed in many countries. However, to best of our knowledge, no previous study has examined triggering Korean women. Thus, aim was establish objective standards for scalp, investigate that trigger this condition, determine ratio women.A total 125 adult women participated study. participants answered questionnaire, had their temperature measured, condition evaluated analyzed.Compared...

Purpose: Acute side effects of radiation such as oral mucositis are observed in most patients.Although several potential radioprotective agents have been proposed, no effective agent has yet identified.In this study, we investigated the effectiveness synthetic compound 3-amino-3-(4-fluoro-phenyl)-1H-quinoline-2,4-dione (KR22332) a agent.Materials and Methods: Cell viability, apoptosis, generation reactive oxygen species (ROS), mitochondrial membrane changes, changes apoptosis-related...

Abstract This study aimed to investigate the impact of nationwide nonpharmaceutical interventions against coronavirus disease 2019 (COVID-19) on incidence Pneumocystis jirovecii pneumonia (PCP) in kidney transplant recipients. The monthly PCP during COVID-19 period decreased significantly compared that pre–COVID-19

We have studied the reliability problems in degradation of data retention characteristics stacked-gate flash EEPROM devices with an oxide–nitride–oxide (ONO) interpoly dielectric. Threshold voltage shift measured as a function bake time at all tested temperatures shows that there are two distinct phases which different dependences on temperature and time; first phase very fast rate threshold while second has gradual rate. Based high-temperature accelerated test, empirical model was developed...