Xiaojuan Hao

ORCID: 0000-0003-2705-0000
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Research Areas
  • Advanced Polymer Synthesis and Characterization
  • Graphene research and applications
  • Nanoparticle-Based Drug Delivery
  • Dendrimers and Hyperbranched Polymers
  • Supercapacitor Materials and Fabrication
  • Nanoplatforms for cancer theranostics
  • Graphene and Nanomaterials Applications
  • biodegradable polymer synthesis and properties
  • Analytical Chemistry and Chromatography
  • Conducting polymers and applications
  • Advanced biosensing and bioanalysis techniques
  • Carbon Nanotubes in Composites
  • Electrospun Nanofibers in Biomedical Applications
  • Ocular Surface and Contact Lens
  • Polymer Surface Interaction Studies
  • Innovative Microfluidic and Catalytic Techniques Innovation
  • Block Copolymer Self-Assembly
  • Hydrogels: synthesis, properties, applications
  • Quantum and electron transport phenomena
  • 2D Materials and Applications
  • Intraocular Surgery and Lenses
  • Pickering emulsions and particle stabilization
  • Microfluidic and Capillary Electrophoresis Applications
  • Sesquiterpenes and Asteraceae Studies
  • 3D Printing in Biomedical Research

Yangzhou University
2025

CSIRO Manufacturing
2015-2024

University of Chinese Academy of Sciences
2023-2024

Wenzhou Medical University
2023-2024

Shanxi Agricultural University
2017-2024

Guangdong Pharmaceutical University
2023

Health Sciences and Nutrition
2016-2022

Northwest A&F University
2021

Hunan Normal University
2020

University of Nebraska–Lincoln
2014-2020

Hollow polyhedrons were structured from carbon-coated CoSe<sub>2</sub> nanospheres bridged by CNTs, and showed a boosted rate capability/robust cyclability for sodium storage.

10.1039/c7ta02665j article EN Journal of Materials Chemistry A 2017-01-01

Abstract Although heat stress reduces seed size in rice (Oryza sativa), little is known about the molecular mechanisms underlying observed reduction and yield. To elucidate mechanistic basis of sensitivity reduced size, we imposed a moderate (34°C) high (42°C) treatment on developing seeds during postfertilization stage. Both treatments final size. At cellular level, resulted precocious endosperm cellularization, whereas severe heat-stressed failed to cellularize. Initiation cellularization...

10.1104/pp.113.232413 article EN PLANT PHYSIOLOGY 2014-03-03

In this study, an injectable, photocurable gelatin system, consisting of acrylated and thiolated gelatin, with tunable mechanical, biodegradation, biological properties was used as a potential cell-supportive scaffold for the repair focal corneal wounds. The mechanical property hydrogels can be readily modified (postcure shear modulus between 0.3 22 kPa) by varying ratio acrylate to thiol groups, photointensity, solid content, biodegradation times also varied change content. More...

10.1021/acsami.7b17054 article EN ACS Applied Materials & Interfaces 2018-04-05

Cellular carbon-wrapped FeSe<sub>2</sub> nanocavities with ultrathin walls and multiple rooms were synthesized by stress-induced cracking–hollowing reassembly processes for sodium storage, showing superb rate capability cyclability.

10.1039/c8ta10614b article EN Journal of Materials Chemistry A 2018-12-17

Stable graphene oxide monoliths (GOMs) have been fabricated by exploiting epoxy groups on the surface of (GO) in a ring opening reaction with amine poly(oxypropylene) diamines (D 400 ). This method can rapidly form covalently bonded GOM D within 60 s. FTIR and XPS analyses confirm formation covalent C‐N bonds. Investigation mechanism reveals that interaction GO diamine cross‐linker result 3 different assemblies depending ratio to GO, which proven both experiment molecular dynamics...

10.1002/adfm.201303815 article EN Advanced Functional Materials 2014-04-23

Well-defined linear poly(acryloyl glucosamine) (PAGA) exhibiting molar masses ranging from 3 to 120 K and low polydispersities have been prepared via reversible addition-fragmentation chain transfer polymerization (RAFT) in aqueous solution without recourse protecting group chemistry. The livingness of the process was further demonstrated by successfully chain-extending one these polymers with N-isopropylacrylamide affording narrow dispersed thermosensitive diblocks. This strategy finally...

10.1021/bm0506086 article EN Biomacromolecules 2005-12-13

Abstract The use of biomacromolecular therapeutics has revolutionized disease treatment, but frequent injections are required owing to their short half‐life in vivo. Thus there is a need for drug delivery system that acts as reservoir and releases the remotely “on demand”. Here we demonstrate simple light‐triggered local through photo‐thermal interactions polymer‐coated gold nanoparticles (AuNPs) inside an agarose hydrogel therapeutic depot. Localized temperature increase induced by visible...

10.1002/anie.201610618 article EN Angewandte Chemie International Edition 2016-12-05

A novel phototheranostic platform based on tri-malonate derivative of fullerene C70 (TFC70)/photosensitizer (Chlorin e6, Ce6) nanovesicles (FCNVs) has been developed for effective tumor imaging and treatment. The FCNVs were prepared from amphiphilic TFC70-oligo ethylene glycol -Ce6 molecules. possessed the following advantages: (i) high loading efficiency Ce6 (up to ∼57 wt%); (ii) efficient absorption in near-infrared light region; (iii) enhanced cellular uptake vitro vivo; (iv) good...

10.1016/j.biomaterials.2016.06.023 article EN cc-by-nc-nd Biomaterials 2016-06-27

Abstract The synthesis and characterization of novel first‐ second‐generation true dendritic reversible addition–fragmentation chain transfer (RAFT) agents carrying 6 or 12 pendant 3‐benzylsulfanylthiocarbonylsulfanylpropionic acid RAFT end groups with Z‐group architecture based on 1,1,1‐hydroxyphenyl ethane trimethylolpropane cores are described in detail. multifunctional have been used to prepare star polymers poly(butyl acrylate) (PBA) polystyrene (PS) narrow polydispersities (1.4 &lt;...

10.1002/pola.20434 article EN Journal of Polymer Science Part A Polymer Chemistry 2004-10-13

Abstract Styrene has been grafted from crosslinked poly(divinylbenzene) core microspheres by both reversible addition fragmentation chain transfer (RAFT) polymerization and conventional free radical polymerization. The were prepared precipitation Crosslinked poly(DVB) containing double bonds on the particle surface can be used directly to graft polymers RAFT without prior modification of microspheres. agent 1‐phenylethyl dithiobenzoate (PEDB) was used: Particle sizes increased 2 μm up 3.06...

10.1002/pola.20328 article EN Journal of Polymer Science Part A Polymer Chemistry 2004-09-07

Herein we provide the first report of a new method for preparation porous functional poly(styrene-co-divinylbenzene) monoliths by use reversible addition–fragmentation chain transfer (RAFT) polymerization. The method, exemplified styrene–divinylbenzene copolymerization in presence 2-cyano-2-propyl dodecyl trithiocarbonate, provides control over polymerization kinetics, monolith morphology and surface functionality. Kinetic studies formation show period slow copolymerization, with rate...

10.1039/c3py01015e article EN Polymer Chemistry 2013-09-02

Self-assembled lipid lyotropic liquid crystalline nanoparticles such as hexosomes and cubosomes contain internal anisotropic isotropic nanostructures, respectively. Despite the remarkable potential of in various biomedical applications, stabilisers used formulating are often limited to commercially available polymers Pluronic block copolymers. This study explored using Reversible Addition-Fragmentation chain Transfer (RAFT) technology design amphiphilic brush-type for purpose stabilising...

10.1039/c6fd00039h article EN Faraday Discussions 2016-01-01

Dual-cross-linked network (DCN) hydrogels with multiresponsive and self-healing properties are attracting intensive interests due to their enhanced mechanical strength for a wide range of applications. Herein, we developed DCN hydrogel that combines dynamic imine benzoxaboronic ester neutral pKa value (∼7.2) as dual linkages contains biocompatible zwitterionic poly(2-methacryloyloxyethyl phosphorylcholine) [poly(MPC)] the backbone. Oscillatory rheology result indicated shear strengthening...

10.1021/acs.biomac.0c01548 article EN Biomacromolecules 2020-12-15

As promising anodes for sodium-ion batteries, metal sulfides ubiquitously suffer from low-rate and high-plateau issues, greatly hindering their application in full-cells. Herein, exemplifying carbon nanotubes (CNTs)-stringed superstructure (CSC) assembled by nano-dispersed SnS2 CoS2 phases, cocktail mediation effect similar to that of high-entropy materials is initially studied ether-based electrolyte solve the challenges. The high nano-dispersity CSC anode underlies cocktail-like effect,...

10.1007/s40820-021-00686-4 article EN cc-by Nano-Micro Letters 2021-08-17

IrC induces immunogenic cell death in melanoma cells and enhances anti-PD-1 immunotherapy by remodeling the tumor microenvironment mice.

10.1039/d3qi00841j article EN Inorganic Chemistry Frontiers 2023-01-01

Antibacterial coatings have drawn much attention because of their high potential applications in medicine. However, the weak mechanical property, poor biosafety, and biocompatibility most established antibacterial restrict applications. In this study, robust were fabricated via a simple organic-inorganic hybrid method. The polymer component provides an excellent property to coatings, silica sol improves hardness coatings. After cross-linking, network-structured formed. coating surfaces...

10.1021/acsami.9b15031 article EN ACS Applied Materials & Interfaces 2019-10-21

We report the design, optimization, and biological evaluation of nuclear receptor RORγ inverse agonists as therapeutic agents for prostate cancer treatment. The most potent compound 27 (designated XY101) exhibited cellular activity with an IC50 value 30 nM in a cell-based reporter gene assay good selectivity against other subtypes. cocrystal structure complex ligand binding domain provided solid structural basis its antagonistic mechanism. potently inhibited cell growth, colony formation,...

10.1021/acs.jmedchem.9b00327 article EN Journal of Medicinal Chemistry 2019-04-09

Abstract The sterically hindered monomers dibutyl itaconate (DBI) and dicyclohexyl (DCHI) were polymerized via reversible addition fragmentation chain transfer (RAFT) free‐radical polymerization. S , ′‐Bis(α,α′‐dimethyl‐α″‐acetic acid) trithiocarbonate, cumyl dithiobenzoate, phenyldithioacetate have been used as RAFT agents to mediate a series of polymerizations at 65 °C yielding rod polymers ranging in number average molecular weight from 9000 92,000 g mol −1 . progress the polymerization...

10.1002/pola.20098 article EN Journal of Polymer Science Part A Polymer Chemistry 2004-04-06
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