A5006178262- Sepsis Diagnosis and Treatment
- Machine Learning in Healthcare
- Cardiac Health and Mental Health
- Intensive Care Unit Cognitive Disorders
- Respiratory Support and Mechanisms
- Sleep and related disorders
- COVID-19 Clinical Research Studies
- Central Venous Catheters and Hemodialysis
- Clinical Reasoning and Diagnostic Skills
- Nosocomial Infections in ICU
- Climate Change and Health Impacts
- Healthcare cost, quality, practices
- Circadian rhythm and melatonin
- Patient Safety and Medication Errors
- Artificial Intelligence in Healthcare
- Heart Failure Treatment and Management
- Dialysis and Renal Disease Management
- Emergency and Acute Care Studies
- Iron Metabolism and Disorders
- SARS-CoV-2 and COVID-19 Research
- COVID-19 diagnosis using AI
- Explainable Artificial Intelligence (XAI)
- Intravenous Infusion Technology and Safety
- Long-Term Effects of COVID-19
- Patient Satisfaction in Healthcare
Nord University
2008-2025
Levanger Hospital
2013-2025
Norwegian University of Science and Technology
2014-2024
St Olav's University Hospital
2021-2024
Central Norway Regional Health Authority
2024
Nordland Hospital Trust
2023
Med-Storm Innovation (Norway)
2023
Oslo University Hospital
2005-2008
We aimed to evaluate the clinical usefulness of qSOFA as a risk stratification tool for patients admitted with infection compared traditional SIRS criteria or our triage system; Rapid Emergency Triage and Treatment System (RETTS). The study was an observational cohort performed at one Department (ED) in urban university teaching hospital Norway, approximately 20,000 visits per year. All >16 years presenting symptoms signs suggesting (n = 1535) were prospectively included from January 1...
AimsThe nature of the association depression and anxiety with risk for acute myocardial infarction (AMI) remains unclear. We aimed to study prospective single recurrent self-reported symptoms a AMI in large Norwegian population based cohort.
Systemic inflammatory response syndrome (SIRS) and sepsis are now frequently identified by observations of vital signs detection organ failure during triage in the emergency room. However, there is less focus on effect patient outcome with better observation treatment at ward level.This was a before-and-after intervention study one community hospital within Mid-Norway Sepsis Study catchment area. All patients confirmed bloodstream infection have been prospectively registered continuously...
Aims Symptoms of anxiety and depression often co‐exist with cardiovascular disease, yet little is known about the prospective risk for heart failure ( HF ) in people symptoms anxiety. We aimed to study these associations using self‐reported anxiety, depression, mixed MSAD a large population sample. Methods results In second wave Nord‐Trøndelag Health Study HUNT 2, 1995–1997), Norway, baseline data on socio‐demographic variables, health status including factors, common chronic somatic...
Few studies have reported on mortality beyond one year after sepsis. We aim to describe trends in short- and long-term among patients admitted with sepsis, the association between clinical characteristics for improved monitoring, treatment prognosis.Patients ≥ 18 years all Norwegian hospitals (2008-2021) a first sepsis episode were identified using Patient Registry International Classification of Diseases 10th Revision codes. Sepsis was classified as implicit (known infection site plus organ...
Abstract The association between pulmonary sequelae and markers of disease severity, as well pro-fibrotic mediators, were studied in 108 patients 3 months after hospital admission for COVID-19. COPD assessment test (CAT-score), spirometry, diffusion capacity the lungs (DL CO ), chest-CT performed at 23 Norwegian hospitals included NOR-SOLIDARITY trial, an open-labelled, randomised clinical investigating efficacy remdesivir hydroxychloroquine (HCQ). Thirty-eight percent had a CAT-score ≥ 10....
Insomnia has been associated with altered inflammatory response as well increased risk of infections and sepsis in observational studies. However, these studies are prone to bias, such residual confounding. To further understand the potential causal association between insomnia risk, a 2-sample Mendelian randomization (MR) approach should be explored.
BackgroundAtrial fibrillation (AF) is the most common sustained cardiac arrhythmia. Anxiety and depression may activate autonomic nervous system which likely to play an important role in etiology of AF. However, little known about association between symptoms anxiety risk AF.ObjectiveThis study aimed assess AF.MethodsIn a population-based study, 37,402 adult residents were followed for incident AF from 2006 2008 until 2015. Participants classified according data on symptoms. Cox proportional...
Abstract Observational studies have indicated an association between iron status and risk of sepsis COVID-19. We estimated the effect genetically-predicted biomarkers on being hospitalized with COVID-19, performing a two-sample Mendelian randomization study. For sepsis, one standard deviation increase in serum was associated odds ratio (OR) 1.14 (95% confidence interval [CI] 1.01–1.29, P = 0.031). The findings were supported analyses for transferrin saturation total binding capacity, while...
Medical histories of patients can predict a patient’s immediate future. While most studies propose to survival from vital signs and hospital tests within one episode care, we carried out selective feature engineering longitudinal medical records in this study develop dataset with derived features. We thereafter trained multiple machine learning models for the binary prediction whether an care will culminate death among suspected bloodstream infections. The classifier performance is evaluated...
Abstract Background Immune dysregulation is a major factor in the development of severe coronavirus disease 2019 (COVID-19). The homeostatic chemokines CCL19 and CCL21 have been implicated as mediators tissue inflammation, but data on their regulation acute respiratory syndrome 2 (SARS-CoV-2) infection limited. We thus investigated levels these COVID-19 patients. Methods Serial blood samples were obtained from patients hospitalized with (n = 414). Circulating during hospitalization 3-month...
To estimate temporal trends in incidence rate (IR) and case fatality during a 14-year period from 2008 to 2021, assess possible shifts these the COVID-19 pandemic.
Bloodstream infections (BSI) and sepsis are important causes of hospitalization, loss health, death globally. Targetable risk factors need to be identified improve prevention treatment. In this study, we aimed evaluate the association chronic kidney disease (CKD) mortality from BSI in general population during a 22-year period.
This study aimed to investigate the predictive capabilities of historical patient records predict adverse outcomes such as mortality, readmission, and prolonged length stay (PLOS).
Peripheral intravenous catheters (PIVCs) account for a mean of 38% catheter associated bloodstream infections (CABSI) with Staphylococcus aureus, which are preventable if deficiencies in best practice addressed. There exists no feasible and reliable quality surveillance tool assessing all important areas related to PIVC quality. Thus, we aimed develop test feasibility reliability an efficient assessment overall The Intravenous Catheter- mini Questionnaire, PIVC-miniQ, consists 16 items...
Abstract Previous studies indicate sex differences in incidence and severity of bloodstream infections (BSI). We examined the effect on risk BSI, BSI mortality, caused by most common infecting bacteria. Using causal mediation analyses, we assessed if this is mediated health behaviours (smoking, alcohol consumption), education, cardiovascular factors (systolic blood pressure, non-HDL cholesterol, body mass index) selected comorbidities. This prospective study included 64,040 participants...
Background Socioeconomic status (SES) may influence risk of sepsis and sepsis-related mortality, but to what extent lifestyle health-related factors mediate this effect is not known. Methods The study included 65 227 participants the population-based HUNT Study in Norway linked with hospital records identify incident deaths. Cox regression estimated HRs mortality associated different indicators SES, whereas mediation analyses were based on an inverse odds weighting approach. Results During...
Sepsis survivors commonly experience functional impairment, which may limit return to work. We investigated work (RTW) of patients hospitalized with sepsis and the associations patient clinical characteristics.Working-age (18-60 years) admitted a Norwegian hospital between 2010 2021 were identified using Patient Registry linked sick-leave data from National Social Security System Registry. The main outcome was proportion RTW in at 6 months, 1 year, 2 years after discharge. Secondary outcomes...
Purpose: Previous research has explored nurses´ experience with the implementation of early detection alert systems, and nurses physicians' perceptions sepsis management use triage. As one first, this study aims to investigate perceived usefulness an interdisciplinary quality improvement project including standardized patient pathway improve identification treatment patients. Participants Methods: This was a qualitative that employed semi-structured interviews thirteen ward five physicians...
In observational studies that use administrative data, it is essential to report technical details such as the number of International Classification Disease (ICD) coding fields extracted. This information crucial for ensuring comparability between and avoiding truncation bias in estimates, particularly complex conditions like sepsis. Specific sepsis codes (explicit sepsis) are suggested be identified by extracting 15 diagnosis fields, while implicit sepsis, which comprises an infection code...