A5076008878- Trypanosoma species research and implications
- Research on Leishmaniasis Studies
- Fungal Biology and Applications
- Medical and Biological Ozone Research
- Synthesis and Biological Evaluation
- Polysaccharides and Plant Cell Walls
- Cytomegalovirus and herpesvirus research
- Phytochemistry Medicinal Plant Applications
- Systemic Lupus Erythematosus Research
- Tendon Structure and Treatment
- Autoimmune and Inflammatory Disorders Research
- Healthcare Regulation
- Biochemical and Molecular Research
- Exercise and Physiological Responses
- Systemic Sclerosis and Related Diseases
- Birth, Development, and Health
- Microbial Metabolites in Food Biotechnology
- HIV/AIDS drug development and treatment
- Occupational health in dentistry
- Dental Research and COVID-19
- Healthcare during COVID-19 Pandemic
- Dental Anxiety and Anesthesia Techniques
- Antifungal resistance and susceptibility
- Rheumatoid Arthritis Research and Therapies
- Nematode management and characterization studies
Universidade Estadual do Oeste do Paraná
2016-2025
Universidade Estadual do Paraná
2014-2025
Universidade Estadual de Campinas (UNICAMP)
2021
Universidade Estadual de Londrina
2003-2004
Cutaneous leishmaniasis is an infectious disease that causes disfiguring scars, which are not eliminated by drugs available to the treatment. Besides, these marks lead economic and social losses. Ozonated oil has wound healing activity as proven in literature, its use with standard treatment could enhance therapy. This study investigated ozonated sunflower adjuvant meglumine antimoniate (MA) of lesions caused Leishmania amazonensis. BALB/c mice were infected parasite, after appeared, they...
One characteristic of autoimmune diseases (ADs) is the production autoantibodies for extractable nuclear autoantigens, which may aid in discrimination different types and related to antinuclear antibody (ANA) patterns. The present study verified profile patient samples tested antigens (ENA) antibodies a public hospital correlated ENA results with ANA patterns diagnoses. reviewed data medical records patients who underwent anti-ENA tests at West State Paraná from February 2011 January 2017....
INTRODUÇÃO: Estudos epidemiológicos brasileiros sobre o lúpus eritematoso sistêmico (LES) são bastante escassos e os dados existentes hoje praticamente todos de literatura internacional. OBJETIVOS: Determinar a incidência algumas características clínicas laboratoriais pacientes com LES em Cascavel, Paraná - Brasil. PACIENTES E MÉTODOS: Os foram coletados entre agosto 2007 julho 2008 serviços saúde do município que possuíam atendimentos na especialidade Reumatologia: um hospital...
Staphylococcus aureus is among the major pathogens involved in food poisoning, and meat contaminated with S. coagulase positive considered a public health risk because bacterium resistant to several conventional antimicrobials. Mycocins are substances produced by yeasts that secrete glycoproteins, which can also be called toxin killers, they have an inhibitory action on other microorganisms. The Wickerhamomyces anomalus, one of microorganisms capable producing these mycocins, resulting...
The immune cross-reactivity between Trypanosoma cruzi, the protozoan that causes Chagas' disease, and Phytomonas serpens, a trypanosomatid infects tomatoes, was studied. Sera from patients with disease presented strong reactivity P. serpens antigens by conventional serological assays such as indirect immunofluorescence (IIF) direct agglutination test (DAT), confirmed after cross-absorption experiments. results show this is highly immunogenic rabbit mouse hyperimmune serum raised against T....
Brazilian epidemiological studies on rheumatoid arthritis are scarce, thus all data currently available originate from the international literature.To determine incidence and some clinical laboratory characteristics of patients with in municipality Cascavel, state Paraná, Brazil.Data were collected between August 2010 July 2011 health services Cascavel that provided care Rheumatology: a university-affiliated hospital, public outpatient clinic four private clinics.We identified 38 diagnosed...
PURPOSE: This study evaluated the rate of microbial contamination toothbrushes used by students and established a protocol for spraying 0.12% chlorhexidine to decrease bacterial presence on bristles brushes. METHODS: We performed cultures selective nonselective media from Dentistry State University West Paraná (Unioeste/PR) identify quantify number total specific microorganisms. For test, crossover double-blind was conducted, with random selection volunteers. Each experimental phase...
Trypanosoma cruzi is the agent of Chagas disease, an infection that affects around 8 million people worldwide. The search for new anti-T. drugs are relevant, mainly because treatment this disease limited to two drugs. objective study was investigate trypanocidal and cytotoxic activity elucidate chemical profile extracts from roots Lonchocarpus cultratus. Roots L. cultratus were submitted successive extractions with hexane, dichloromethane, methanol, resulting in LCH, LCD, LCM extracts,...
Chagas disease is a neglected tropical with only two drugs available for treatment and the plant Cecropia pachystachya has several compounds antimicrobial anti-inflammatory activities. This study aimed to evaluate supercritical extract from C. leaves in vitro vivo against Trypanosoma cruzi. A CO2 extraction was used obtain (CPE). Cytotoxicity immunostimulation ability were evaluated macrophages, trypanocidal activity epimastigotes trypomastigotes forms. In tests done by infecting BALB/c mice...
Aim and objective: This study aimed to evaluate the effect of ozonated water used as an irrigant dentin-cleaning solution on bond strength fiberglass pins in vitro, comparing it with commonly solutions.Material methods: Seventy-seven bovine roots were randomly divided into seven groups according be used: HP/HP, 2.5% sodium hypochlorite; DA/DA, distilled water; CHX/CHX, 2% chlorhexidine; OA/OA, 4 ppm HP/DA; HP/CHX; HP/OA.In each group, root canals endodontically prepared by using...
Ganoderma australe was studied to determine the composition of cell wall, and polysaccharide fraction SK5 obtained after freeze-thawing an aqueous 5% potassium hydroxide extraction. The monosaccharide revealed by gas chromatography-mass spectrometry showed 81.3% glucose, analyses 13C nuclear magnetic resonance spectroscopy confirmed a β-glucan with glycosidic links (1→3)-β type most likely 4-O substituted. In addition, biological effect from G. evaluated via in vitro cultures peritoneal...
Introduction: Trypanosoma cruzi is the agent of Chagas’ disease and affects approximately 6-8 million people worldwide. The search for new anti-T. drugs are relevant because only two exist actually. objective this study was to investigate effect extracts from seeds Lonchocarpus cultratus on T. cruzi, its cytotoxicity as well elucidate chemical profile.
 Methodology: characterization done using 1H-RMN. forms were treated with increasing concentrations after, percentage inhibition IC50 or...
Aims This study aimed to characterize and evaluate leishmanicidal trypanocidal action as well cytotoxicity on macrophages antioxidant ability of extracts, obtained by supercritical CO2 ultrasound-assisted extractions Uvaia (Eugenia pyriformis) leaves. Methods Leaves from E. pyriformis were submitted (E1) (E2) extractions. The characterization extracts was done using GC-MS HPLC. L. amazonensis (promastigotes) T. cruzi (epimastigotes trypomastigotes) treated with crescent concentrations E1 E2....