A5068967377- Dermatology and Skin Diseases
- Food Allergy and Anaphylaxis Research
- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Contact Dermatitis and Allergies
- Healthcare and Venom Research
- Eosinophilic Esophagitis
- Traditional Chinese Medicine Studies
- Diverse Approaches in Healthcare and Education Studies
- Nutrition, Health and Food Behavior
- Pediatric health and respiratory diseases
- Effects and risks of endocrine disrupting chemicals
- Sepsis Diagnosis and Treatment
- Advancements in Transdermal Drug Delivery
- Psychosocial Factors Impacting Youth
- Urticaria and Related Conditions
- Emergency and Acute Care Studies
- Air Quality and Health Impacts
- IL-33, ST2, and ILC Pathways
- Exercise and Physiological Responses
- Skin Protection and Aging
- Obesity, Physical Activity, Diet
- Respiratory and Cough-Related Research
- Neonatal Respiratory Health Research
- Eating Disorders and Behaviors
Kosin University Gospel Hospital
2019-2025
Samsung Medical Center
2017-2025
Sungkyunkwan University
2005-2025
Chungnam National University
2024
Samsung (South Korea)
2024
Korea Brain Research Institute
2023
Kosin University
2017-2020
ORCID
2020
University of Fukui
2019
Yonsei University
2009-2018
We aimed to investigate epidermal lipid profiles and their association with skin microbiome compositions in children atopic dermatitis (AD).Specimens were obtained by tape stripping from 27 AD 18 healthy subjects matched for age sex. Proteins lipids of stratum corneum samples nonlesional lesional patients normal quantified liquid chromatography tandem mass spectrometry. Skin analyzed using bacterial 16S rRNA sequencing.Ceramides nonhydroxy fatty acids (FAs) C18 sphingosine as sphingoid base...
Long-standing or repeated skin barrier damage followed by atopic dermatitis (AD) is the initial step of march that eventually progresses to respiratory allergies. Maintenance an acidic pH in stratum corneum (SC) important factor for normal function. We performed this study determine whether oxazolone (Ox)-induced AD murine model can develop airway inflammation topical application and nasal inhalation a house dust mite, Dermatofagoides pteronyssinus (Dp), which novel 'atopic animal model', SC...
Among ElectroActive Polymers (EAPs) the dielectric elastomer actuator is regarded as one of most practically applicable in near future. So far, its effect on actuation phenomena has not been discussed sufficiently, although strong dependency prestrain a significant drawback an actuator. Recent observations clarifies that following pros and cons: plays important role generating large strain, whereas it rather contributes to reduction strain. Prestrain provides advantages improving response...
Please cite this paper as: Topical calcineurin inhibitors compromise stratum corneum integrity, epidermal permeability and antimicrobial barrier function. Experimental Dermatology 2010; 19: 501–510. Abstract Background: (TCIs) such as pimecrolimus tacrolimus have recently been used for dermatologic diseases including atopic dermatitis instead of topical glucocorticoids, because they display comparable efficacy, but less‐frequent side effects. Although even short‐term glucocorticoid...
This study aimed to evaluate the reliability and validity of Korean version Food Allergy Quality Life Questionnaire-Parent Form (K-FAQLQ-PF) identify clinical characteristics related low quality life (QoL) in children with food allergy (FA).Parents 0-12-year-old patients FA were enrolled. The English FAQLQ-PF was translated into Korean. Construct validation confirmed by Independent Measure-Parent (FAIM-PF) Child Health Questionnaire Parent 28 (CHQ-PF28). Logistic regression analyses used...
Despite the high workload of mechanical ventilation, there has been a lack studies on association between nurse workforce and mortality in mechanically ventilated patients. We evaluated bed-to-nurse ratio with pediatric patients admitted to an intensive care unit (ICU).We conducted nationwide retrospective analysis by using Korean National Health Insurance database, which categorizes into 9 grades according number beds divided full-time equivalent registered nurses unit. Patients ages 28...
Atopic dermatitis (AD) is a chronic inflammatory skin disorder characterized by immune dysregulation, pruritus, and abnormal epidermal barrier function. Compared with conventional mesenchymal stem cell (MSC), induced pluripotent (iPSC)-derived (iMSC) recognized as unique source for producing extracellular vesicles (EVs) because it can be obtained in scalable manner an enhanced homogeneity. Stimulation of iMSCs cytokines improve the immune-regulatory, anti-inflammatory, tissue-repairing...
Exposure to heavy metals such as lead, cadmium, and mercury poses serious health risks pregnant women because of their high toxicity. In this study, we investigated the associations metal exposure with birth outcomes Korean infants. Data 5,215 between 2015 2019 were analyzed. This study was part Children's Environmental Health (Ko-CHENS) study. Linear regression logistic analyses used examine effects concentrations on weight, small for gestational age, large age after adjusting maternal...
Short Communication Sustained Unresponsiveness in Oral Immunotherapy for Cow’s Milk Allergy Sukyung Kim 1,†, Minji 2,†, Jiwon 2, Minyoung Jung 3, Ji Young Lee 4, Kangmo Ahn 1,5 and Jihyun 1,5,* 1 Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School Medicine, Seoul 06351, Korea 2 Chungnam National Sejong Hospital, 30099, 3 Kosin Gospel College Busan 49267, 4 Hallym Chuncheon Sacred Heart 24253, 5 Health Sciences Technology, Advanced Institute & 06355, *...
Objectives The purpose of this study is to identify trends and derive future research directions based on the analysis data previous studies college liberal major. Methods According collection stage, 39 papers published from 2008 2024 (November) were selected as data. Research analyzed using five criteria. As tools, ‘EXCEL’ big tool ‘Textom’ used generate descriptive statistics visualization Results First, major rapidly increasing in line with policy trend Ministry Education. Second, most...
The presence of congenitally impaired skin barrier followed by atopic dermatitis (AD) is an initial step in the march. maintenance acidic pH stratum corneum (SC) has been suggested as a therapeutic or preventive strategy for impairment caused inflammation. To determine whether AD murine model, flaky tail mice, with inherited filaggrin deficiency could develop airway inflammation repeated topical application nasal inhalation house dust mite (HDM) antigen (defined novel "atopic march animal...
To compare mortality rate, the adjustment of case-mix variables is needed. The Pediatric Index Mortality (PIM) 3 score a widely used system pediatric intensive care unit (ICU), but there has been no validation study it in Korea. We aim to validate PIM3 Korean ICU, and extend from those aged 0-16 0-18 years, as patients 16-18 years are admitted ICU A retrospective cohort 1,710 was conducted tertiary ICU. score, discriminatory power assessed by calculating area under receiver-operating...
Objectives The aim of this review is to analyze research trends on the Korean medical treatment and study fracture. Methods We searched 38 studies related fracture via medicine web databases. classified these by three types (experimental reports, case reports retrospective reports) researched how treat patient Results were published since 1993 every year 2004 2013. There 8 experimental 20 10 reports. Most effective Bee venom Hua-Tuo-Jia-Ji-Xue acupuncture more than general treatment....
Background: The acidic pH of the stratum corneum (SC) is important for epidermal permeability barrier homeostasis.Acidification skin surface has been suggested as a therapeutic strategy disorders such atopic dermatitis (AD).Objective: We performed an animal study to evaluate usefulness acidification SC inhibition AD lesions and find out if effect vinegar attributable its herbal contents, rather than acidity.Methods: Five groups six oxazolone-treated (Ox)-AD mice were treated three weeks with...
Atopic dermatitis (AD) is a heterogeneous disease with different age of onset, course, clinical symptoms, severity, and risk comorbidity. The characteristics children AD also vary by or country. However, little known about the in Korean school-aged adolescents. Furthermore, there are few studies on phenotypic differences according to onset age. This study aimed explore phenotypes severity adolescents Korea.AD patients aged 6-18 years who presented 18 hospitals nationwide were surveyed....
Food allergy (FA) can have a profound effect on quality of life (QoL), stress, and anxiety in the family. We aimed to validate Korean version Allergy Quality Life-Parental Burden (FAQL-PB) identify factors related parental psychosocial burden caring for children with FAs.Parents aged between 6 months 17 years immunoglobulin E (IgE)-mediated FAs from Pediatric Department five university hospitals Korea were enrolled study. Parents asked complete FAQL-PB, Independent Measure-Parent Form...
Shellfish and fish are common causes of food allergy (FA) in Asia, with significant prevalence rates reported across various countries. This study aimed to identify the diagnostic decision points (DDPs) for shrimp, crab, cod allergies Korean children. We enrolled participants aged 18 years or younger suspected through a retrospective review medical records from nationwide 14-center between January 2018 March 2022. FA was diagnosed using an open oral challenge reproducible convincing history...
It is necessary to evaluate the parental ability achieve nutritional adequacy while avoiding allergens for children with food allergies (FA), yet this area currently understudies. Our study aimed develop and validate Parental Self-Efficacy Scale Dietary Management of Children Food Allergies (PSED-FA). PSED-FA was developed through a literature review semi-structured interviews refined by panel five allergists dietitians, validated using responses from caregivers FA. The construction tool...