A5078080625- AI in cancer detection
- Genetic and phenotypic traits in livestock
- Prenatal Screening and Diagnostics
- Ovarian cancer diagnosis and treatment
- Pregnancy and preeclampsia studies
- Bacterial Genetics and Biotechnology
- Urologic and reproductive health conditions
- Conflict of Laws and Jurisdiction
- Endometrial and Cervical Cancer Treatments
- Genital Health and Disease
- Bacteriophages and microbial interactions
- Congenital gastrointestinal and neural anomalies
- Reproductive Biology and Fertility
- Reproductive Physiology in Livestock
- Genomics and Phylogenetic Studies
- Uterine Myomas and Treatments
- Protein Structure and Dynamics
- Reproductive System and Pregnancy
- Animal Behavior and Welfare Studies
- Genetic factors in colorectal cancer
- Endometriosis Research and Treatment
- Gynecological conditions and treatments
- Genetic Associations and Epidemiology
- Protist diversity and phylogeny
University of Tartu
2022-2025
Toxin-antitoxin (TA) systems are a large group of small genetic modules found in prokaryotes and their mobile elements. Type II TAs encoded as bicistronic (two-gene) operons that encode two proteins: toxin neutralizing antitoxin. Using our tool NetFlax (standing for Network-FlaGs toxins antitoxins), we have performed large-scale bioinformatic analysis proteinaceous TAs, revealing interconnected clusters constituting core network TA-like gene pairs. To understand the structural basis...
Abstract Accurate placenta pathology assessment is essential for managing maternal and newborn health, but the placenta’s heterogeneity temporal variability pose challenges histology analysis. To address this issue, we developed ‘Histology Analysis Pipeline.PY’ (HAPPY), a deep learning hierarchical method quantifying of cells micro-anatomical tissue structures across whole slide images. HAPPY differs from patch-based features or segmentation approaches by following an interpretable...
Abstract Study question Can a large-scale GWAS meta-analysis identify the genomic risk loci and associated candidate genes for FGT polyps? Summary answer We identified ten loci, with two exonic missense variants in PRIM1 COL17A1 genes, highlighting shared mechanisms cancerous processes. What is known already Small-scale gene studies have focused on biological processes such as oestrogen stimulation inflammation to clarify biology behind polyps. However, exact mechanism development of polyps...
Toxin-antitoxin (TA) systems are a large group of small genetic modules found in prokaryotes and their mobile elements. Type II TAs encoded as bicistronic (two-gene) operons that encode two proteins: toxin neutralising antitoxin. Using our tool NetFlax (standing for Network-FlaGs toxins antitoxins) we have performed large-scale bioinformatic analysis proteinaceous TAs, revealing interconnected clusters constituting core network TA-like gene pairs. To understand the structural basis...
Abstract Accurate placenta pathology assessment is essential for managing maternal and newborn health, but the placenta’s heterogeneity temporal variability pose challenges histology analysis. To address this issue, we developed ‘Histology Analysis Pipeline.PY’ (HAPPY), a deep learning hierarchical method quantifying of cells micro-anatomical tissue structures across whole slide images. HAPPY differs from patch-based features or segmentation approaches by following an interpretable...
Abstract STUDY QUESTION Can a large-scale genome-wide association study (GWAS) meta-analysis identify the genomic risk loci and associated candidate genes for female genital tract (FGT) polyps, provide insights into mechanism underlying their development, inform potential overlap with other traits, including endometrial cancer? SUMMARY ANSWER GWAS of FGT polyps highlighted potentially shared mechanisms between polyp development cancerous processes. WHAT IS KNOWN ALREADY Small-scale gene...
The aetiology of foetal presentation in cattle is still unresolved. hind legs are the main source propulsive movement cattle, which provides changes presentation. assumption that absence leg movements foetus, as case congenital malformation, Perosomus elumbis, incidence anterior and posterior will be same. Scopus database, world wide web (www), list article references were searched using keyword, elumbis. Manuscripts with data about included 21 cases 16 articles identified. There 11 10...