- Intestinal and Peritoneal Adhesions
- Herpesvirus Infections and Treatments
- Virus-based gene therapy research
- Cardiac, Anesthesia and Surgical Outcomes
- Hernia repair and management
- Virology and Viral Diseases
- Foreign Body Medical Cases
- Abdominal Surgery and Complications
- Platelet Disorders and Treatments
- Cellular transport and secretion
- Veterinary Oncology Research
- Parathyroid Disorders and Treatments
- Hepatitis B Virus Studies
- Extracellular vesicles in disease
- Glycogen Storage Diseases and Myoclonus
- Inflammatory Biomarkers in Disease Prognosis
- Magnesium in Health and Disease
- RNA regulation and disease
- Diverticular Disease and Complications
- Gastrointestinal Tumor Research and Treatment
- Case Reports on Hematomas
- Colorectal Cancer Surgical Treatments
- Cancer-related molecular mechanisms research
- Appendicitis Diagnosis and Management
- Fungal and yeast genetics research
Okayama University
2023-2025
Okayama University Hospital
2025
Mito Saiseikai General Hospital
2020-2023
Nara Institute of Science and Technology
2022
Tokushima University
2006
Gifu University
2000
Kyushu University
1968
Abstract Background The mechanisms by which neutrophils acquire pro-tumor properties remain poorly understood. In pancreatic cancer, cancer-associated fibroblasts (CAFs) may interact with neutrophils, directing them to promote tumor progression. Methods To validate the association between CAFs and localization of was examined in clinically resected cancer specimens. were produced culturing cancer-conditioned media, effects these on examined. vitro migration invasion assays assess effect...
Abstract Background: Chemotherapy resistance is a major contributor of the poor prognosis pancreatic cancer, yet its underlying mechanisms remain poorly understood. Neutrophil Extracellular Traps (NETs), form neutrophil-specific cell death, have been reported to be associated with in various cancers because they act suppress tumor immunity and promote metastasis. Recently, chemotherapy-stimulated NETs, termed “ChemoNETosis”, were contribute chemotherapy breast cancer (Mousset A, Cancer cell....
Abstract Background: Regarding the sidedness of colorectal cancer, right-sided cancer (RCRC) and left-sided (LCRC) originate from midgut hindgut, respectively. It is known that in stages III IV, RCRC has a poorer prognosis compared to LCRC. Furthermore, liver metastasis (CRLM) also varies depending on primary tumor's sidedness. Although differences such as MSI-H status, BRAF mutations, histological types have been noted between right- cancers, clinical observations recognized treatment...
Proline is the most abundant amino acid in wine and beer, because yeast Saccharomyces cerevisiae hardly assimilates proline during fermentation processes. Our previous studies showed that arginine induces endocytosis of transporter Put4, resulting inhibition utilization. We here report a possible role sensing first found two basic acids, ornithine, lysine, inhibit utilization by inducing Put4 manner similar to arginine, but citrulline does not. genetic screening revealed Can1 involved...
[in Japanese]
A hematoma that gradually increases over a chronic course of months or longer is defined as expanding (CEH). CEHs often develop in the limbs and on body surfaces are susceptible to external stimuli. intrathoracic intraperitoneal organs uncommon, with liver being particularly rare worldwide.A 57-year-old woman was previously diagnosed giant cyst right lobe, axis approximately 15 cm. Abdominal ultrasonography findings suggested complex cyst, she referred our hospital for further inspection....
Abstract Background In this retrospective study, we aimed to assess the predictive factors for bowel resection due strangulated small obstruction (SSBO). Methods We enrolled a total of 109 patients diagnosed with SSBO at surgery. They were divided into two groups: those who underwent and did not. The clinical findings, blood test results, gas analysis computed tomography (CT) sequential organ failure assessment (SOFA) scores examined compared between groups. Results group (n = 38) non-bowel...
Abstract Purpose In this retrospective study, we assessed factors that can be used to predict the need for bowel resection due an incarcerated groin hernia. Methods We enrolled a total of 83 patients diagnosed with hernia on preoperative unenhanced computed tomography (CT) between January 2010 and December 2019 in our hospital. They were divided into two groups: those who underwent did not. The clinical findings, blood test results, CT values examined compared groups. indication intestinal...
Abstract Background: In this retrospective study, we aimed to assess the predictive factors for bowel resection due strangulated small obstruction (SSBO). Methods: We enrolled a total of 109 patients diagnosed with SSBO at surgery. They were divided into two groups: those who underwent and did not. The clinical findings, blood test results, gas analysis computed tomography (CT) sequential organ failure assessment (SOFA) scores examined compared between groups. Results: A univariate indicated...