A5002457245- Mosquito-borne diseases and control
- Viral Infections and Vectors
- MicroRNA in disease regulation
- Vector-borne infectious diseases
- Viral Infections and Immunology Research
- Cytomegalovirus and herpesvirus research
- Garlic and Onion Studies
- Extracellular vesicles in disease
- Viral gastroenteritis research and epidemiology
- Respiratory viral infections research
- Studies on Chitinases and Chitosanases
- Cancer-related molecular mechanisms research
- Parvovirus B19 Infection Studies
- Iron Metabolism and Disorders
- Synthesis and biological activity
- Tannin, Tannase and Anticancer Activities
- RNA and protein synthesis mechanisms
- Phytochemical compounds biological activities
- Herpesvirus Infections and Treatments
- Hemoglobinopathies and Related Disorders
- Genomics, phytochemicals, and oxidative stress
- Kawasaki Disease and Coronary Complications
- Ocular Diseases and Behçet’s Syndrome
Sanjay Gandhi Post Graduate Institute of Medical Sciences
2015-2024
Allium sativum L. has been used medicinally and traditionally since antiquity. This study sought to examine the ethanolic extract (ASEE) in inducing apoptosis human triple-negative breast cancer (TNBC) MDA-MB-231 cells molecular interactions of identified components with cell death markers using silico method. Cytotoxicity ASEE was tested on MCF-7, MDA-MB-231, Normal Vero cells. The ROS production, apoptosis, MMP, cycle were conducted utilizing flow cytometer, western blot also performed for...
Japanese encephalitis is one of the serious vector-borne viral diseases found worldwide and poses a major threat to public health. Most virus (JEV) infections are subclinical; only 1: 250 1:1000 infected persons develop clinical presentations. Delay in proper diagnosis JE affects timeliness treatment initiation increases mortality rate patients. Therefore, there an extreme need potential biomarkers, which might improve can become basis for development new therapeutics. The microRNAs...
Vaccine is the most effective preventive measure against Japanese Encephalitis infection. Role of IFN‐γ expressing T cells for JE virus clearance has been described as a part cellular immunity. induced immunity also involve immune response, therefore study was aimed to observe induction and persistence by ELISpot assay. The cell count increased significantly after 28 ( P < 0.0001) days post vaccination, remained higher at all time points (day 28, day 180, 360) when compared with...
Over a third of diabetes patients develop diabetic nephropathy. To categorize such subset there is need for non‐invasive biomarker that regulate very early in the pathogenesis. We tested miRNAs urinary exosomes (UE) as candidate molecule using serial urine sample from rats before and during course diabetes. Wistar were injected with streptozotocin (50 mg/kg. body weight). For exosome isolation, samples collected (ND) after induction. Differentially expressed identified small RNA sequencing,...
Identifying potential biomarkers, which can be used for diagnostic and therapeutic purposes, is urgently needed successful Japanese encephalitis (J.E.) viral infection disease management. In the present study, we identified key CSF protein biomarkers of J.E. patients. We compared them to those from non-JE acute syndrome other neurological non-infectious patients determine their discriminatory detect JEV infection. Demographic clinical information including fever, headache, vomiting, altered...
Abstract Background Acute flaccid paralysis (AFP), characterized by the rapid onset of asymmetric paralysis, can be caused a variety viral infections or coinfections. Besides wild-type and revertant vaccine strains polioviruses, several nonpolio enteroviruses, have also been associated with AFP. Enteroviruses (EVs) are RNA viruses in family Picornaviridae comprising more than 100 serotypes that divided into four species, human enteroviruses A to D. The clinical manifestations EVs range from...
Japanese encephalitis virus (JEV) is one of the most important causes acute and uncontrolled inflammatory disease in Asia. Matrix metalloproteinases (MMPs) chemokines play a detrimental role host response to JE disease, aetiology, outcome. Evidently, MMPs are widely circulated brain regulate various process including microglial activation, inflammation, blood-brain barrier disruption as well affects central nervous system (CNS). The present study was assess association single nucleotide...