A5047686171- Retinal and Optic Conditions
- Ocular Oncology and Treatments
- Ocular Diseases and Behçet’s Syndrome
- Cytomegalovirus and herpesvirus research
- Global Health and Surgery
- Ophthalmology and Visual Impairment Studies
- Nonmelanoma Skin Cancer Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Glaucoma and retinal disorders
- Systemic Lupus Erythematosus Research
- Anesthesia and Neurotoxicity Research
- Ocular Disorders and Treatments
- Intraocular Surgery and Lenses
- Herpesvirus Infections and Treatments
- Cutaneous Melanoma Detection and Management
- Retinal and Macular Surgery
- Corneal Surgery and Treatments
- Autoimmune and Inflammatory Disorders
- Nicotinic Acetylcholine Receptors Study
- Hematopoietic Stem Cell Transplantation
- Scoliosis diagnosis and treatment
- Parasitic Diseases Research and Treatment
- Fetal and Pediatric Neurological Disorders
- Trigeminal Neuralgia and Treatments
- Brain Metastases and Treatment
Bayero University Kano
2016-2025
Aminu Kano Teaching Hospital
2014-2024
NIHR Leeds Musculoskeletal Biomedical Research Unit
2021-2024
University of Leeds
2024
Leeds Teaching Hospitals NHS Trust
2021-2024
Versus Arthritis
2021
British Society for Rheumatology
2021
Icahn School of Medicine at Mount Sinai
2011
Hairmyres Hospital
2004
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease that affects spinal cord and cortical motor neurons. An increasing amount of evidence suggests mitochondrial dysfunction contributes to neuron death in ALS. Peroxisome proliferator-activated receptor gamma co-activator-1α (PGC-1α) principal regulator biogenesis oxidative metabolism.In this study, we examined whether PGC-1α plays protective role ALS by using double transgenic mouse model where over-expressed an...
The travel distance from home to a treatment centre, which may impact the stage at diagnosis, has not been investigated for retinoblastoma, most common childhood eye cancer. We aimed investigate burden and its on clinical presentation in large sample of patients with retinoblastoma Africa Europe.A cross-sectional analysis including 518 treatment-naïve residing 40 European countries 1024 43 African countries.Capture rate was 42.2% expected 108.8% Europe. were older (95% CI -12.4 -5.4,...
Background and Objective HIV-associated retinopathy other ocular complications remain conditions of concern despite the introduction combination antiretroviral therapy (ART). Evaluating people living with HIV (PLWH) for early hemodynamic changes in their ophthalmic arteries using Doppler ultrasonography is crucial to modifying care preventing potential retinal damage. Methods This case-control study included 150 eligible adults on ART an equal number age- sex-matched apparently healthy...
Background: Cycloplegic refraction is important in assessing children with hypermetropia. Atropine, though the gold standard cycloplegic agent for children, has a long duration of action and more severe side effects compared to short-acting agents. The aim study was compare effect atropine cyclopentolate tropicamide combination Subjects Methods: This crossover interventional using two separate regimens drugs done on all subjects. Data were analyzed statistical software SPSS version 22.0....
The prevalence and nature of corneal astigmatism among patients with cataract has not been well-documented in the resident African population. This retrospective study was undertaken to investigate preexisting adult cataract. We analyzed keratometric readings acquired by manual Javal-Schiotz keratometry before surgery between January 1, 2011 December 31, 2011. There were 3,169 (3286 eyes) aged 16 110 years involved a Male female ratio 1.4:1. Mean diopters K1 = 43.99 K2 43.80. 1.16 diopter...
Filarial worms are tissue-dwelling nematodes that can infest man. The adult filarial parasites, depending on the species, may live in lymphatics, blood vessels, serous membranes, skin, or connective tissues [1]. Loa loa worm lives commonly tissues, eyelids, and subconjunctiva, where it be seen moving across conjunctival sac [2]. Instances of intraocular occurrence rare, few cases which were reported earlier presence Wuchereria bancrofti either vitreous anterior chamber [3,4]. Ocular loiasis...
Background: Uncorrected refractive errors are a major cause of blindness and low vision. Determination the etiology is essential in planning appropriate treatment modalities. Aim this study was to determine correlation between axial length corneal power with status patients error Kano, Nigeria. Methods: Observational cross-sectional which 385 eligible were recruited. Relevant history obtained from ocular examination done. Objective Subjective refraction performed. Spherical equivalent...
Aim: This study aims to determine the effect of pterygium excision on degree corneal induced astigmatism and visual acuity. Patients Methods: was a prospective interventional conducted between September 2012 June 2013. Consecutive patients with who met inclusion criteria were recruited into study. They had basic eye examination, those existing comorbidity excluded. Selected using bare sclera technique intraoperative application Mitomycin C. Detailed pre- post-operative evaluation refraction...
Background: To review the common indications for intravitreal anti vascular endothelial growth factor (VEGF) medications given at retinal unit of Makkah Specialist Eye Hospital, Kano, Nigeria from January 2014 to December 2015.Methods: The case records all patients VEGF were reviewed and age, diagnosis indication injection recorded. Results analyzed using PAWS statistics version 18.0 (SPSS Inc., Chicago, IL).Results: A total 174 injections consisting 170 bevacizumab 4 ranibizumab in study...
Human immunodeficiency virus (HIV) is a pandemic disease affecting all regions across the globe and Nigeria having second highest prevalence worldwide. Highly active antiretroviral therapy (HAART) has profound negative effect on optic nerve even though improved health status of affected individuals overall reduction in mortality. Imaging modality especially ultrasound great role assessment because its availability, affordability, easy operability with reliable sensitivity.This...
<h3>Background:</h3> The consideration of intensive therapy in SLE depends on disease severity, resistance, or reimbursement issues. Evaluating the baseline predicting factors for earlier decisions to initiate high-risk patients is an unmet need. Thus, we assessed predictors requirements such a novel early strategy prevent severe and accrual damage. <h3>Objectives:</h3> To investigate clinical biomarkers time-to-requirement from diagnosis. <h3>Methods:</h3> We conducted retrospective...
Morning glory syndrome (MGS) is uncommon in Nigeria as less commonly seen Africans. It one of the congenital excavated optic disc dysplasia apart from coloboma and peripapillary staphyloma. We report a case morning anomaly (MGDA) with associated retinal detachment 9 year old boy, who presented complaint poor vision left eye incidentally noticed when he covered right following trivial trauma to eye. Ocular examination revealed best corrected visual acuity 6/5 no perception light (NPL)...
Craniofacial duplication known as diprosopus is a rare congenital disorder whereby parts or all of the face are duplicated on head. This case 1-year-old boy referred to our hospital with an extra eye (third eye) left side head and abnormally shaped head, which were noticed since birth. Pregnancy delivery uneventful. Apart from routine antenatal medication, there was no history suggestive ingestion traditional other medication during pregnancy. No smoking pregnancy exposure radiation. The...
Context: Conjunctiva is a transparent membrane lining the inner surface of eyelids and globe up to corneoscleral limbus. It common site for growth lesions in eye. Depending on their origin, conjunctival could be non-neoplastic neoplastic. The neoplastic are either benign or malignant. These can distinguished based patient's history, clinical presentation histopathological features. Aims: In this study, pattern excised was determined. Methods Material: This 6-year (2010–2015) retrospective...
Background: Human cytomegalovirus (HCMV) is a leading cause of opportunistic infection in HIV-infected patients. HCMV viraemia an active marker and prelude to end-organ diseases (EODs), such as retinitis. The aim the study was assess burden associated factors infection, retinitis among patients Nigeria.Methods: Comparative cross-sectional 160 adults, comprising 80 participants each <100/mm3 ≥100 cells/mm3 CD4+ cell count groups, who attended HIV clinic at tertiary hospital located major...
Waardenburg syndrome (WS) is associated with hearing loss and an autosomal inherited disorder genetic heterogeneity. WS types 1 2 depict a high degree of inter- intrafamilial variabilities, type being less common than 2. In Northern Nigeria, due to cultural religious inclinations, consanguineous marriages are quite common; thus, inheritable genes easily passed on from one generation the next. Following paucity reports this in Nigeria its rarity worldwide, we report case familial variability...
Abstract Background: Migraine is a group of headache syndromes, with prevalence 5%–25%. complex recurrent disorder, often unilateral, throbbing or pulsating in nature aggravated by physical activity, bright light, and loud noises. Symptoms associated migraine without aura are nausea, anorexia, varying degrees ophthalmic problems ranging from visual aura, ocular symptoms, ophthalmoplegia. Objectives: The study determined the pattern manifestations Aminu Kano Teaching Hospital, Kano, Nigeria....
Background: Glaucoma constitutes a serious health problem in Nigeria and beyond. It is leading cause of bilateral blindness its burden remains high. There paucity literature on the levels circulating brain-derived neurotrophic factor (BDNF) disease among Africans. In addition, dynamics reasons for variation BDNF local population glaucoma patients are yet to be demonstrated. Objective: This study determined level factors associated with it patients. Materials Methods: Serum concentration...
Purpose: Accommodative-convergence mechanism failure could occur in non presbyopic HIV- sero positive patients on Highly Active Anti-Retroviral Therapy (HAART). This be due to either direct neuronal infection by HIV, pathologic changes of the lens or ciliary body adverse effects some individual drugs constituting HAART regimen cranial nerves which play vital roles accommodation and convergence.
 Case report: is a case report an accommodative- convergence HIV 32-year-old male patient...
Highly Active Anti-Retroviral Therapy (HAART) has been effective in reducing rapidly progressive retinopathies, there are other ocular manifestations of HIV and side effects HAART which yet to be determined evaluated. The aim this study was investigate evaluate the effect on Visual Acuity (VA) Intraocular Pressure (IOP) among HIV/AIDS patients Kano State, Nigeria. This a prospective hospital based cross-sectional study; consented that fulfilled inclusion criteria were recruited grouped into...
To report the rare case of a patient with bilateral uveitis meningococcal septicaemia from Neisseria meningitides, resulting to blindness and adjustment disorder. A 9-years-old boy presented Emergency paediatric unit hospital complaints fever, neck stiffness one week duration. There was associated sudden decreased vision, pain photophobia both eyes. Neck stiff retracted positive Kernig’s Brudzinski’s signs. meningitidis isolated turbid CSF blood. Visual Acuity (VA) Perception Light (PL)...
Background: SLE is heterogeneous in clinical presentation, underlying immunology, and response to therapy. Patients with severe or resistant disease receive cyclophosphamide rituximab. Although effective, late use of these therapies entails cumulative damage. Emerging predictors rituximab include demographics, IFN-Scores autoantibodies. For such change treatment strategy we need understand their association the effectiveness other therapeutic options at earlier decision points. Prospective...
Albinism is a heterogenous group of disorders melanin synthesis or distribution that genetically inherited. Refractive errors are common in participants with albinism and high values have been reported. The aim this study was to determine the pattern refractive people living North-Western Nigeria. This prospective hospital-based study, carried out over 12 months from April 2017-March 2018 (12 months) whereby persons Kano Jigawa states were recruited. Ethical approval obtained ethical review...