A5102961497- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Cardiac Structural Anomalies and Repair
- Acute Myocardial Infarction Research
- Vascular Procedures and Complications
- Cardiac Valve Diseases and Treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Angiogenesis and VEGF in Cancer
- Coronary Artery Anomalies
- Cardiac Arrhythmias and Treatments
- Mechanical Circulatory Support Devices
- Cardiac Arrest and Resuscitation
- Cerebrovascular and Carotid Artery Diseases
- Central Venous Catheters and Hemodialysis
- Cardiac tumors and thrombi
- Venous Thromboembolism Diagnosis and Management
- Aortic aneurysm repair treatments
- Infective Endocarditis Diagnosis and Management
- Lymphatic System and Diseases
- Non-Invasive Vital Sign Monitoring
- Cardiac electrophysiology and arrhythmias
- Heart Rate Variability and Autonomic Control
- Mobile Health and mHealth Applications
- Congenital Heart Disease Studies
- Heparin-Induced Thrombocytopenia and Thrombosis
Antwerp University Hospital
2016-2025
University of Antwerp
2014-2025
Cardiogenic shock (CGS) occurs in 10% of patients presenting with acute myocardial infarction (MI), in-hospital mortality rates 40-50% despite revascularisation.
Aims: Cardiogenic shock (CGS) occurs in 6-10% of patients with acute coronary syndromes (ACS). Mortality has fallen over time from 80% to approximately 50% consequent on revascularisation but plateaued since the 1990s. Once established, CGS develop adverse compensatory mechanisms that contribute downward spiral towards death, which becomes difficult reverse. We aimed test a robust, prospective, randomised controlled trial whether early support veno-arterial extracorporeal membrane...
Mobilization of bone marrow-derived endothelial progenitor cells (EPC) might explain exercise-induced improvement function. We assessed whether a maximal exercise bout could alter the number circulating EPC in healthy subjects and this effect is related to their cardiovascular risk profile. Additionally, we investigated possible mediators effect, namely nitric oxide (NO) bioavailability vascular growth factor (VEGF) release. Healthy (group 1, n = 11; group 2, 14) performed symptom-limited...
Cannabis is a frequently used recreational drug that potentially imposes serious health problems.We report three cases where recent and/or chronic use of marijuana led to severe cardiac dysfunction. All patients collapsed at home and required cardiopulmonary resuscitation (CPR) with initial restoration spontaneous circulation (ROSC).The mechanism the cardiovascular collapse was different in each case. The first case presented asystole found have diff coronary vasospasm on angiography hours...
To evaluate the first experience of real-time instantaneous wave-free ratio (iFR) measurement by clinicians.
<h3>Objective:</h3> To investigate the underlying mechanisms of a decreased coronary flow reserve after myocardial infarction (MI) by analysing characteristics diastolic hyperaemic pressure–flow relationship. <h3>Design:</h3> Prospective study. <h3>Setting:</h3> Tertiary care hospital. <h3>Patients:</h3> 68 patients with recent MI and 27 stable angina pectoris (AP; control group). <h3>Main outcome measures:</h3> The intercept pressure axis (the zero or Pzf) slope index relationship (SIPF)...
The present observational case-control study assessed the cost-effectiveness of contemporary vascular closure devices (VCDs) for prevention complications in an all-comers transfemoral percutaneous coronary intervention (PCI) population.A total 8,292 consecutive PCI patients were enrolled from a single-centre prospective registry January 2005 to December 2010. VCDs available July 2007 and, that time point, implanted 1,780 5,394 (33%). Vascular occurred 221 (2.7%) patients. use was...
Models of experimental ischemia-reperfusion (IR) in adiponectin knockout animals have shown that mediates protection against the development IR injury. However, role injury humans is largely unknown. In a total 234 ST segment elevation myocardial infarction (STEMI) patients, baseline circulating concentration was correlated with after primary percutaneous coronary intervention (pPCI) and major adverse cardiac events (MACE, death hospitalization) during one year follow up. defined by serial...
<b><i>Background:</i></b> MicroRNA are noncoding RNA that have a significant role in both inflammatory and cardiovascular diseases. <b><i>Aims:</i></b> We aimed to assess whether the inflammation-related microRNA-155 is associated with development of adverse left ventricular (LV) remodeling following ST elevation myocardial infarction (STEMI). <b><i>Methods:</i></b> Peripheral blood samples were collected (day 2),...
To evaluate differences in strut coverage, inflammation and endothelialization between two second-generation polymer-based drug-eluting stents (DES) an atherosclerotic rabbit double-injury iliac artery model at 28 days follow-up.Rabbits with induced atheroma received bilateral stents: everolimus-eluting stent (Xience V EES; Abbott Vascular), zotarolimus-eluting (Resolute ZES; Medtronic CardioVascular), or bare-metal (BMS; MultiLink Vision; Vascular). After days, total neointimal coverage...
Abstract Objectives The study aimed to demonstrate through instant wave‐free ratio (iFR) measurements that myocardium distal a chronic total occlusion (CTO) is ischemic, ischemia reversible by PCI, and iFR assessment after PCI can be used optimize results. Background greatest benefit of revascularization found in patients with low fractional flow reserve. In CTOs, measurement may more appropriate evaluate as it does not require maximal microvascular vasodilation, which hampered dysfunction....
A 64-year-old-man underwent routine elective right-left heart catheterization, 1 year after cardiac transplantation for terminal ischaemic cardiomyopathy. Surprisingly, selective coronary angiography disclosed coronary–pulmonary artery fistula with three feeding vessels originating from the proximal right artery, portion of left anterior descending circumflexus and main draining into pulmonary trunk. For this particular patient, without any significant complaints or symptoms, normal...
Abstract Atrioventriculardissociation can be amanifestationof an underlying noncardiacdisease.We present a patient who underwent pacemaker implantation because of intermittent atrioventricular dissociation and medically untreatable supraventricular arrhythmias, which could not induced by electrophysiological testing. The arrhythmias proved to due pheochromocytoma. After left adrenalectomy, both the disappeared. Adequate recognition treatment pheochromocytoma reverse may avoid unnecessary...