A5001536723- Vestibular and auditory disorders
- Hearing, Cochlea, Tinnitus, Genetics
- Hearing Loss and Rehabilitation
- Ear Surgery and Otitis Media
- Ear and Head Tumors
- Semiconductor materials and devices
- Head and Neck Surgical Oncology
- Head and Neck Cancer Studies
- Noise Effects and Management
- Magnetic properties of thin films
- Voice and Speech Disorders
- Animal Disease Management and Epidemiology
- Surgical Simulation and Training
- Glaucoma and retinal disorders
- Cerebral Venous Sinus Thrombosis
- Diet, Metabolism, and Disease
- Cholesterol and Lipid Metabolism
- Sinusitis and nasal conditions
- Liver Disease Diagnosis and Treatment
- Ferroelectric and Negative Capacitance Devices
- Vector-Borne Animal Diseases
- Cancer Diagnosis and Treatment
- Explainable Artificial Intelligence (XAI)
- Foreign Body Medical Cases
- Balance, Gait, and Falls Prevention
Samsung (South Korea)
2019-2025
Korea University
2017-2025
Seoul St. Mary's Hospital
2018-2024
Catholic University of Korea
2018-2024
Kosin University
2023
Sengkang General Hospital
2023
St. Vincent's Hospital
2022
Samsung (United Kingdom)
2017
High density 1Gb embedded STT-MRAM in 28nm FDSOI technology was successfully demonstrated. Based on the highly reliable and manufacturable eMRAM technology, high yield over 90% achieved at operating temperature from −40°c to 105°c with satisfying read, write function 10 years retention 105°c. These results are mainly attributed advanced process for better control of MTJ CD, window robust circuit design chip. properties can be systematically adjusted by tailoring stack module process....
7nm CMOS FinFET technology featuring EUV lithography, 4 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">th</sup> gen. dual Fin and 2 xmlns:xlink="http://www.w3.org/1999/xlink">nd</sup> multi-eWF gate stack is presented, providing 20% faster speed or consuming 35% less total power over 10nm [1]. fully applied to MOL contacts minimum-pitched metal/via interconnects, can reduce >25% mask steps with higher fidelity smaller CD variation. A <inf...
Hearing rehabilitation with auditory training (AT) is necessary to improve speech perception ability in patients hearing loss. However, face-to-face AT has not been widely implemented due its high cost and personnel requirements. Therefore, there a need for the development of patient-friendly, mobile-based program.
Abstract We demonstrate the mechanism by which C3G, a major dietary anthocyanin, regulates energy metabolism and insulin sensitivity. Oral administration of C3G reduced hepatic plasma triglyceride levels, adiposity, improved glucose tolerance in mice fed high-fat diet. Hepatic metabolomic analysis revealed that shifted metabolite profiles towards fatty acid oxidation ketogenesis. increased uptake HepG2 cells C2C12 myotubes induced rate oxidation. directly interacted with activated PPARs,...
African swine fever (ASF), a highly contagious and severe hemorrhagic viral disease in swine, is emerging as major threat not only Korea but also worldwide. The first confirmed case of ASF was reported 2019. Despite the occurrence Korea, few studies have genetically characterized causative virus (ASFV). In this study, we aimed to characterize ASFV responsible for 2019 outbreak Korea. genome isolated during analyzed. Korea/YC1/2019 strain has 188,950 base pairs, with GC content 38.4%....
Objectives: Vitamin D deficiency as a risk factor of tinnitus has not been well known. We tried to evaluate the association between serum 25-(OH) vitamin levels and among Korean population propose possible role in patients with tinnitus. Methods: This cross-sectional study investigated potential factors relation 25(OH)D within population. It encompassed health interview, nutrition assessment, examination. Data was sourced from KNHANES V (2010-2012), conducted by Division Health Nutritional...
Endoscopic sinus and skull base surgeries are minimally invasive surgical techniques that reduce postoperative symptoms complications enhance patients' quality of life. However, to ensure excellent outcomes after such interventions, intimate familiarity with important landmarks high-level endoscope manipulation skills essential. Cadaver training is one possible option, but cadavers expensive, scarce, nonreusable cadaver work requires specialized equipment staff. In addition, it difficult...
In this paper, we studied the mechanism of triglyceride (TG)-lowering effect kaempferol in vitro and vivo. Kaempferol showed LXR agonistic activities without inducing TGs or expression several lipogenic genes cultured cells. A luciferase qPCR analysis that increased transactivation PPARα PPARδ stimulated gene associated with fatty acid oxidation uptake hepatocytes. More importantly, inhibited protein kinase B (Akt) activity suppressed SREBP-1 activation via multiple mechanisms, including...
Objective To examine the effect of xylitol nasal irrigation in a large sample size patients who had undergone surgery. Study Design Double‐blinded randomized controlled crossover study. Setting Tertiary referral center. Methods The study included 100 with sinonasal disease underwent endoscopic sinus surgery (ESS), septoplasty, or both concurrently. identify allergic sensitization, serum‐specific immunoglobulin E levels were measured. Nasal symptoms evaluated NOSE (Nasal Obstruction Symptoms...
Objective Review of a sigmoid sinus diverticuli (SSDi) variants surgically managed with novel technique using an inferior periosteal flap. Study Design Case series. Setting Tertiary referral center. Patients presenting pulsatile tinnitus to tertiary center between January 1, 2015, and June 31, 2021, who were diagnosed SSDi on CT temporal bone received surgical management for these variants. Intervention(s) Obliteration inferiorly based Main Outcome Measure(s) Pure-tone audiometry, Tinnitus...
We demonstrate embedded STT-MRAM fully integrated onto 28nm CIS logic platform, highlighting the world-best macro density of 13.94 Mb/mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> . The provides 55% area saving over SRAM. MTJ processes are compatible with standard 3D-stacked integration that require sufficient 400°C heat budget. stack has also been improved for frame buffer applications, achieving write speed <50ns and endurance...
Alpha-lipoic acid (ALA) is an antioxidant with oto-protective effects. In the present study, safety and effectiveness of ALA therapy after noise-induced hearing loss was confirmed based on administration method. The intratympanic (IT-ALA) evaluated oto-endoscopy middle ear mucosa morphologic study. Perilymph concentrations according to routes were compared, efficacy investigated through tests cochlear histological studies. swollen 1 week IT-ALA but completely recovered within 3 weeks....
African swine fever (ASF), a contagious and lethal haemorrhagic disease of domestic pigs wild boars, poses significant threat to the global pig industry. Although experimental vaccine candidates derived from naturally attenuated, genetically engineered, or cell culture-adapted ASF virus have been tested, no commercial is accepted globally. We developed safe effective cell-adapted live attenuated candidate (ASFV-MEC-01) by serial passage field isolate in CA-CAS-01-A cells. ASFV-MEC-01,...
Despite sufficient hearing gains, many patients with loss have difficulty using aids due to poor word recognition ability. This study was performed introduce our rehabilitation therapy (HRT) program for aid users and evaluate its effect on improvement.In this prospective randomized case-control study, 37 participants moderate or moderate-severe sensorineural who had used bilateral more than 3 months functional gain were enrolled in study. Nineteen randomly assigned the control group (CG) 18...
Abstract Background Although cigarette smoking is the most significant risk factor for laryngeal cancer, other factors might also be associated with development of cancer. We investigated whether underweight and type 2 diabetes are cancer in a Korean population. Methods A total 9,957,059 participants (≥20 years) without prior history who underwent National Health Insurance Service health checkup 2009 were followed up until December 31, 2018. Newly diagnosed was identified using claim data,...
Background: The preventative effect of melatonin on the development obesity and progression fatty liver under a high-fat diet (HFD) has been well elucidated through previous studies. We investigated mechanism behind this regarding cholesterol biosynthesis regulation levels.Methods: Mice were divided into three groups: normal chow (NCD); HFD; HFD administration group (HFD+M). assessed serum lipid profile, mRNA expression levels proteins involved in synthesis reabsorption nutrient transporters...
The objective of this study was to investigate current perception and expected price personal sound amplification products (PSAPs) analyze influencing factors through multi-center hospital-based surveys outpatients, caregivers, hearing experts.A exploratory cross-sectional conducted in two groups respondents with separate surveys: 1) a survey patients caregivers who visited an otorhinolaryngology outpatient clinic 5 general hospitals 2) opinion specialists about the PSAPs. A total 197...
Background and Objectives Tinnitus retraining therapy (TRT) is one of the most effective treatment methods for tinnitus. This study aimed to evaluate response TRT in tinnitus patients with hearing loss analyze an additive effect aid.Subjects Method In this retrospective observational case-control study, we reviewed medical records 80 who were diagnosed sensorineural mild moderate managed by TRT. The changes after or without aids measured questionnaire visual analog scale (VAS) Handicap...
Due to high demand but limited supply, there has been an increase in the need replace autologous bone grafts with alternatives that fulfill osteogenic requirements. In this study, two different types of were tested for their drug carrying abilities along properties. Two alendronate-loaded grafts, Bio-Oss (bovine graft) and InRoad (biphasic synthetic observed see how concentrations alendronate would affect sustained release enhance osteogenesis. defected ovariectomize-induced osteoporotic rat...