A5067857334- Celiac Disease Research and Management
- Microscopic Colitis
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Biomedical Research and Pathophysiology
- Folate and B Vitamins Research
- Connective tissue disorders research
- Metabolism and Genetic Disorders
- Renal Diseases and Glomerulopathies
- Sexual Differentiation and Disorders
- Parathyroid Disorders and Treatments
- Mitochondrial Function and Pathology
- RNA regulation and disease
- Lysosomal Storage Disorders Research
- Kidney Stones and Urolithiasis Treatments
- Esophageal and GI Pathology
- Epilepsy research and treatment
- RNA and protein synthesis mechanisms
- RNA modifications and cancer
- Heavy Metal Exposure and Toxicity
- Pregnancy and Medication Impact
- Craniofacial Disorders and Treatments
- Eosinophilic Esophagitis
- Trace Elements in Health
- Hormonal and reproductive studies
- Fetal and Pediatric Neurological Disorders
University of Monastir
2011-2013
Military Hospital of Tunis
2010-2013
Hospital Fatuma Bourguiba Monastir
2010-2012
The oxidant stress, expected to increase in obese adults, has an important role the pathogenesis of many diseases. It results when free radical formation is greatly increased or protective antioxidant mechanisms are compromised. main objective this study evaluate response obesity-related stress healthy children.A hundred and six children (54 52 controls), aged 6-12 years old, participated study. collected data included anthropometric measures, blood pressure, fasting glucose, total...
The frequency of primary resistance to antibiotics in H. pylori isolates is increasing worldwide. In Tunisia, there are limited data regarding the pattern antibiotic resistance.To evaluate clarithromycin, metronidazole and amoxicillin detect mutations involved clarithromycin resistance.273 strains isolated from adults children were enrolled. was evaluated by means E-test minimal inhibitory concentration (MIC). real-time PCR using Scorpion primers performed all cases assess point involved.No...
<b>Background:</b> IL–4 is a determining factor in immunologic mechanisms to allergy and inflammation. The authors designed case–controlled study investigate the potential association of repeat polymorphism gene with specific clinical phenotypes asthma. <b>Methods:</b> used polymerase chain reaction characterize variation intron 2 region 145 unrelated Tunisian patients asthma 160 healthy control subjects. In order strengthen study, analysis was performed families...
Introduction Congenital dysfibrinogenemia is a rare qualitative fibrinogen deficiency. Molecular defects that result in are usually caused by mutations which affect fibrinopeptide release, fibrin polymerization, cross‐linking or fibrinolysis. Aim Here, we investigated the genetic basis of hypodysfibrinogenemia two Tunisian siblings with major bleeding. Methods Coagulation‐related tests were performed on patients and their family members. Functional analysis was plasma to characterize...
Glycogen storage disease type III (GSD III) is an autosomal recessive disorder caused by the deficiency of glycogen debranching enzyme (AGL). It characterized hepatomegaly, progressive myopathy, cardiomyopathy and fasting hypoglycemia. Several mutations in AGL gene have been described different populations. The W1327X mutation was reported one Tunisian patient resident Italy. We looked this report to determine frequency among patients. screening 26 GSD patients originated from various...
To investigate fertility in a sample of Tunisian patients with congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency. bicentric prospective study. Endocrinology department, Hedi Chaker Hospital, Sfax, Tunisia and Department Internal Medicine, Tahar Sfar Mahdia, Tunisia. Twenty-six (11 M; 15 F), aged 16.5–48 years, were enrolled. Clinical, biological, hormonal ultrasound examinations performed assess fertility. Eighteen had the classical form eight non classic. One patient...
West syndrome is the most frequent cause of epilepsy in Down syndrome. often associated with poor long-term prognosis children. We report a girl which occurred at 8 months age for repetitive flexor spasms and electroencephalography (EEG) showed hypsarrhythmia. She had facies, microcephaly, psychomotor development delay axial hypotonia. Computed tomography brain was normal. Her karyotype 47, XX, +21. Phenobarbital therapy immediately effective good clinical control seizures, while EEG...