A5020030473- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Cardiac Valve Diseases and Treatments
- Acute Myocardial Infarction Research
- ECG Monitoring and Analysis
- Cardiovascular Function and Risk Factors
- Ion channel regulation and function
- Cardiovascular Effects of Exercise
- Infective Endocarditis Diagnosis and Management
- Pericarditis and Cardiac Tamponade
- Cardiomyopathy and Myosin Studies
- Cardiac Structural Anomalies and Repair
- Cardiovascular Syncope and Autonomic Disorders
- Antiplatelet Therapy and Cardiovascular Diseases
- Venous Thromboembolism Diagnosis and Management
- Advanced MRI Techniques and Applications
- Cerebrovascular and Carotid Artery Diseases
- HIV-related health complications and treatments
- Myasthenia Gravis and Thymoma
- Pulmonary Hypertension Research and Treatments
- Health Systems, Economic Evaluations, Quality of Life
University of Turin
2016-2025
Maria Cecilia Hospital
2024
University of Lübeck
2024
University Hospital Schleswig-Holstein
2024
Azienda Ospedaliera Citta' della Salute e della Scienza di Torino
2013-2023
Ospedale Maria Vittoria
2014-2023
Ospedale Policlinico San Martino
2023
A. O. Ordine Mauriziano di Torino
2001-2023
University of Trieste
2023
Hospital Maria Pia
2023
Background— Sudden cardiac death takes the lives of more than 300 000 Americans annually. Malignant ventricular arrhythmias occurring in individuals with structurally normal hearts account for a subgroup these sudden deaths. The present study describes genetic basis new clinical entity characterized by and short-QT intervals ECG. Methods Results— Three families hereditary syndrome high incidence were studied. In 2 them, we identified different missense mutations resulting same amino acid...
Background— Brugada syndrome is characterized by ST-segment elevation in the right precordial leads and an increased risk of sudden cardiac death (SCD). Fundamental questions remain on best strategy for assessing real disease-associated arrhythmic risk, especially asymptomatic patients. The aim present study was to evaluate prognosis factors SCD patients FINGER (France, Italy, Netherlands, Germany) registry. Methods Results— Patients were recruited 11 tertiary centers 4 European countries....
A prolonged QT interval is associated with a risk for life-threatening events. However, little known about prognostic implications of the reverse-a short interval. Several members 2 different families were referred syncope, palpitations, and resuscitated cardiac arrest in presence positive family history sudden death. Autopsy did not reveal any structural heart disease. All patients had constantly uniformly at ECG. Six from both submitted to extensive noninvasive invasive work-up, including...
Background— Ventricular fibrillation is the main mechanism of sudden cardiac death. The feasibility eliminating recurrent episodes by catheter ablation has not been reported. Methods and Results— Twenty-seven patients without known heart disease (13 men, 14 women, 41±14 years age) were studied after being resuscitated from (10±12) primary idiopathic ventricular fibrillation; 23 had received a defibrillator. first initiating beat an identical electrocardiographic morphology coupling interval...
Ablation of the slow pathway has been performed to eliminate atrioventricular (AV) nodal reentrant tachycardia (AVNRT) either by a surgical approach or using radiofrequency catheter technique guided retrograde activation mapping. From previous experience midseptal and posteroseptal mapping, we were aware existence peculiar potentials in most humans. Postulating their role AVNRT, studied these effects energy.Sixty-four patients (mean age, 48 +/- 19 years) with usual form AVNRT studied. Slow,...
Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is a condition associated with the risk of sudden death (SD).We conducted multicenter study impact implantable cardioverter-defibrillator (ICD) for prevention SD in 132 patients (93 males and 39 females, age 40+/-15 years) ARVC/D. Implant indications were history cardiac arrest 13 (10%), sustained tachycardia 82 (62%), syncope 21 (16%), other 16 (12%). During mean follow-up 39+/-25 months, 64 (48%) had appropriate ICD...
Radiofrequency left atrial catheter ablation has become a routine procedure for treatment of fibrillation. The aim this study was to assess with preprocedural and postprocedural cerebral magnetic resonance imaging the thromboembolic risk, either silent or clinically manifest, in context fibrillation ablation. secondary end point identification clinical procedural parameters that correlate embolism.A total 232 consecutive patients paroxysmal persistent who were candidates radiofrequency...
Clinical presentation, occurrence of sudden infant death, and results the available therapies in largest group patients with short QT syndrome (SQTS), studied so far, are reported. history, physical examination, electrocardiogram (ECG), exercise stress testing, electrophysiological study, morphological evaluation, genetic analysis therapy 29 SQTS personal and/or familial history cardiac arrest The median age at diagnosis was 30 years (range 4-80). In all subjects, structural heart disease...
InvestigatorsIMPORTANCE Postpericardiotomy syndrome, postoperative atrial fibrillation (AF), and effusions may be responsible for increased morbidity health care costs after cardiac surgery.Postoperative use of colchicine prevented these complications in a single trial.OBJECTIVE To determine the efficacy safety perioperative oral reducing postpericardiotomy AF, pericardial or pleural effusions. DESIGN, SETTING, AND PARTICIPANTSInvestigator-initiated, double-blind, placebo-controlled,...
<h3>Importance</h3> Anakinra, an interleukin 1β recombinant receptor antagonist, may have potential to treat colchicine-resistant and corticosteroid-dependent recurrent pericarditis. <h3>Objective</h3> To determine the efficacy of anakinra for <h3>Design, Setting, Participants</h3> The Anakinra—Treatment Recurrent Idiopathic Pericarditis (AIRTRIP) double-blind, placebo-controlled, randomized withdrawal trial (open label with followed by a double-blind step or placebo until pericarditis...
AF Ablation Technologies and Silent Cerebral Ischemic Lesions. Introduction: cerebral ischemic lesions have recently emerged as the most frequent complications after pulmonary vein isolation (PVI). To reduce thromboembolic complications, new types of catheters energy source been introduced in clinical practice. The study purpose is to compare incidence silent events patients with paroxysmal atrial fibrillation (PAF) undergoing PVI different ablation technologies. Methods Results: One hundred...
Orthopedic strain and radiation exposure are recognized risk factors in personnel staff performing fluoroscopically guided cardiovascular procedures. However, the potential occupational health effects still unclear. The purpose of this study was to examine prevalence problems among working interventional cardiology/cardiac electrophysiology correlate them with length exposure.We used a self-administered questionnaire collect demographic information, work-related lifestyle-confounding...
Brugada syndrome poses significant challenges in terms of risk stratification and management, particularly for asymptomatic patients who comprise the majority individuals exhibiting ECG pattern (BrECG). The aim this study was to evaluate long-term prognosis a large cohort with BrECG.
Background —Knowledge of the electrophysiological substrates and cure atrial fibrillation (AF) is still unsatisfactory. The goal this study was to evaluate features idiopathic AF their relationship results radiofrequency (RF) catheter ablation safety effectiveness procedure. Methods Results —Sixteen patients with underwent mapping during then RF in right atrium. activation simultaneously recorded four regions atrium: high lateral wall (HL), low (LL), septum (HS), (LS) left atrium through...