- Venous Thromboembolism Diagnosis and Management
- Diagnosis and Treatment of Venous Diseases
- Central Venous Catheters and Hemodialysis
- Receptor Mechanisms and Signaling
- Peripheral Artery Disease Management
- Neurotransmitter Receptor Influence on Behavior
- Vascular Procedures and Complications
- Aortic aneurysm repair treatments
- Neuroscience and Neuropharmacology Research
- Cerebrovascular and Carotid Artery Diseases
- Ultrasound in Clinical Applications
- Neuropeptides and Animal Physiology
- Cardiac, Anesthesia and Surgical Outcomes
- HER2/EGFR in Cancer Research
- Aortic Disease and Treatment Approaches
- Entomological Studies and Ecology
- CRISPR and Genetic Engineering
- Radiation Dose and Imaging
- Cardiac Valve Diseases and Treatments
- Renal and Vascular Pathologies
- Hormonal Regulation and Hypertension
- Adrenal and Paraganglionic Tumors
- Medical Imaging and Pathology Studies
- Vascular anomalies and interventions
- Tracheal and airway disorders
University Hospital Galway
2016-2025
Ollscoil na Gaillimhe – University of Galway
2017-2022
Royal College of Surgeons in Ireland
2004-2017
Mater Misericordiae University Hospital
2015
St Vincent's Hospital Sydney
2015
University College Hospital
2006-2014
University College London
2006-2014
Health Service Executive
2011
Institut Gustave Roussy
2006
Institute of Oncology Ljubljana
2006
Abstract Purpose To assess safety and patency of the Venovo venous stent for treatment iliofemoral vein obstruction. Materials Methods Twenty-two international centers enrolled 170 patients in VERNACULAR study (93 post-thrombotic syndrome; 77 non-thrombotic iliac lesions). Primary outcome measures were major adverse events at 30 days 12-month primary (freedom from target vessel revascularization, thrombotic occlusion, or stenosis > 50%). Secondary outcomes included Venous Clinical...
Purpose To report 36-month outcomes and subgroup analysis of the ABRE Study evaluating safety effectiveness Abre venous self-expanding stent system for treatment symptomatic iliofemoral outflow obstruction disease. Methods The was a prospective, multicenter, non-randomized study that enrolled implanted stents in 200 participants (mean age 51.5±15.9 years 66.5% women) with at 24 global sites. Outcomes assessed through 36 months included patency, major adverse events, migration, fracture,...
Activation of dopamine D1 receptors (D1Rs) has been shown to induce epileptiform activity. We studied the molecular changes occurring in hippocampus response administration D1-type receptor agonist, SKF 81297. 81297 at 2.5 and 5.0 mg/kg induced behavioural seizures. Electrophysiological recordings dentate gyrus revealed presence discharges peaking 30-45 min post-injection declining by 60 min. Seizures were prevented antagonist, SCH 23390, or cannabinoid CB1 CP 55,940. The effect was...
Summary Objective To describe clinical practice experience of 11 C‐Metomidate PET/CT as an adjunct to adrenal vein sampling (AVS) in the lateralization aldosterone‐producing adenomas (APA) primary aldosteronism (PA). Context Accurate APA setting PA offers potential for surgical cure and improved long‐term cardiovascular outcomes. Challenges associated with AVS, current gold standard modality, mean that only a small proportion potentially eligible patients currently make it through surgery....
Interventional radiology (IR) has come a long way to nowadays UEMS-CESMA endorsed clinical specialty. Over the last decades IR became an essential part of modern medicine, delivering minimally invasive patient-focused care.To provide principles for high quality care in IR.Systematic description skills, practice, organizational standards and infrastructure needed provision professional services.There are procedures almost all body parts organs, covering broad range medical conditions. In many...
The neuregulin-1 gene is widely expressed in the central nervous system and associated with increased risk for schizophrenia. Using an ethologically based approach, phenotype of heterozygous knockout mice was examined by revealing individual elements behaviour murine repertoire over prolonged course interaction environment. During initial exploration, mutants displayed a characterized increases locomotion rearing free, sex-specific alterations sifting grooming. Over subsequent habituation,...
Abstract Purpose To describe the outcomes of a survey on provision interventional radiology procedures for treatment acute pulmonary embolism (PE) in Europe and beyond. Methods An online with 14 structured items was designed by authors sent to 7116 CIRSE members via email. The anonymous collected data eight weeks; only complete responses were statistically analysed. Results completed 373 (5.24%). Among these, 75.1% worked at centres offering catheter-directed thrombolysis or thrombectomy,...