- Venomous Animal Envenomation and Studies
- Rabies epidemiology and control
- Environmental Impact and Sustainability
- Energy, Environment, Economic Growth
- Anesthesia and Pain Management
- Light effects on plants
- Anesthesia and Sedative Agents
- Medical Imaging Techniques and Applications
- MicroRNA in disease regulation
- Diabetes and associated disorders
- Radiomics and Machine Learning in Medical Imaging
- Intensive Care Unit Cognitive Disorders
- Anesthesia and Neurotoxicity Research
- Bioactive Natural Diterpenoids Research
- Climate Change Policy and Economics
- Automotive and Human Injury Biomechanics
- Water Resources and Sustainability
- University Challenges and Reforms
- IgG4-Related and Inflammatory Diseases
- Immune Cell Function and Interaction
- Innovative Educational Techniques
- Service-Learning and Community Engagement
- Advanced Differential Geometry Research
- Neuropeptides and Animal Physiology
- Advanced Graph Theory Research
Sun Yat-sen University
2017-2025
Sun Yat-sen Memorial Hospital
2017-2025
Guangxi Medical University
2006-2024
Kunming Medical University
2023-2024
Hubei University of Chinese Medicine
2024
Nantong University
2022-2023
Nanjing Forestry University
2023
National Institute of Biological Sciences, Beijing
2021
Jiangsu Institute of Meteorological Sciences
2020
Nanjing Agricultural University
2017-2018
Abstract Appetitive locomotion is essential for animals to approach rewards, such as food and prey. The neuronal circuitry controlling appetitive unclear. In a goal-directed behavior—predatory hunting, we show an excitatory brain circuit from the superior colliculus (SC) substantia nigra pars compacta (SNc) enhance in mice. This tectonigral pathway transmits locomotion-speed signals dopamine neurons triggers release dorsal striatum. Synaptic inactivation of this impairs but not defensive...
Prunella vulgaris plants (full-bloom stage) were subjected to short-term (15 days) UV-B radiation in a growth chamber. was effective at enhancing morphological and biomass characteristics decreasing chlorophyll contents of P. vulgaris. Treatment with artificial significantly increased peroxidase (POD), superoxide dismutase (SOD) glutathione (GSH) activities compared the control treatment. levels hydrogen peroxide (H2O2), malondialdehyde (MDA) proline leaves those plants. In addition, total...
The effects of UV-B radiation on the content bioactive components and antioxidant activity Prunella vulgaris L. spica during development were studied. experimental design involved two levels intensity (0 120 μW cm-2 nm-1). results showed that contents total flavonoids, rosmarinic acid, caffeic acid hyperoside, as well capacities (DPPH● ABTS•+ scavenging activities), in spicas significantly decreased development. salviaflaside increased highest activities found full-flowering stage, while...
The Yangtze River Economic Belt (YEB) and the Yellow Ecological (YREB) surround two biggest inland rivers emit greatest amount of carbon emissions in China. In order to implement China's dual goal, this research applies a Meta-frontier DN-DEA model, including reduction factor (CRF), assess emission efficiency energy, CO2, atmospheric pollutants for total 19 regions YEB YREB from 2011 2017. Synergistic climate risk control economic belts are verified by tests CO2 three kinds pollutant...
In recent years, the research on post operational cognitive dysfunction (POCD) has received increasing attention. Some patients may experience complications such as mental disorder and memory impairment after gynecological laparoscopic surgery, which are cognitive, social, personality issues of postoperative patients. This article divided surgery into three groups based different BIS (biological index) ranges. Before clinical use, artificial intelligence was used to sort out patients'...
Background: This study is supposed to investigate the effects of combined epidural and general anesthesia on intraoperative hemodynamic responses, postoperative cellular immunity, prognosis in patients with gallbladder cancer (GBC). Methods: One hundred forty-four GBC were selected randomly divided into (GA) group epidural-general (CEGA) group. Before induction (t0), at intubation (t1), beginning surgery (t2), 5 minutes after pneumoperitoneum (t3), end (t4), recovery spontaneous breathing...
Previously, we demonstrated that follicle stimulating hormone (FSH) enhanced VEGF expression and facilitated ovarian cancer angiogenesis via the PI3K/AKT signaling pathway. In this study, further investigated involvement of microRNA-27a: ZBTB10‑specificity protein pathway in mechanism FSH-induced VEGF, Cox2 survivin expression. Treatment with FSH resulted significant increase Cox2, survivin, Sp1 proteins microRNA-27a a dose-dependent manner, whereas reverse pattern was observed ZBTB10....
Background: Catheter-related bladder discomfort (CRBD) to an indwelling urinary catheter is defined as a painful urethral discomfort, resistant conventional opioid therapy, decreasing the quality of postoperative recovery. According anatomy, branches sacral somatic nerves form afferent urethra and triangle, which deriving from ventral rami second fourth spinal nerves, innervating muscles sphincter perineum pelvic floor; well providing sensation penis clitoris in males females, including...
A large-scale persistent strong dense fog (SDF) event that occurred from December 30, 2016, to January 5, 2017, in central and eastern China is analyzed by using a variety of data, including high-resolution satellite surface observations, meteorological tower fine-resolution sounding NCEP/NCAR reanalysis data. The results show the following: (1) SDF has characteristics long duration, wide influence range, large intensity, serious air pollution. During study period, there are 531 stations...
In the current study, we scrutinized effect of sevoflurane and halothane on cognitive immune function in young rats. The rats were divided into following groups: sevoflurane, + groups, respectively. regularly treated with pre-determined treatment. We also serum proinflammatory cytokines including IL-10, IL-4 IL-2; brain level IL-1β; hippocampal neuronal apoptosis concentration estimated. water maze test was performed for estimation ability. During test, 1st day group showed latency;...
With rapid population growth and productivity development, the contradiction between economic social development resource environmental protection is becoming increasingly prominent, so it important to study regional carrying capacity protect environment promote high-quality development. This takes three major urban agglomerations of Beijing-Tianjin-Hebei, Yangtze River Delta Pearl as research objects, uses entropy-weighted topsis model obstacle diagnosis evaluate comprehensive levels...
The new development form of urban agglomeration has greatly promoted economic and social progress in recent years, but it is also facing severe environmental pollution problems. Understanding the status quo efficiency agglomerations its leading driving forces an important prerequisite for formulating energy conservation emission reduction policies. This research uses Meta Epsilon Based Measure (Meta-EBM) model to measure Beijing-Tianjin-Hebei(BTH), Yangtze River Delta (YRD) Pearl (PRD) China...
Bungarus multicinctus is one of the top ten venomous snakes in China, and its bite causes acute severe diseases, but pathophysiology remains poorly elucidated. Thus, an animal model was established by intramuscular injection 30μg/kg venom, then serum metabolites were subsequently screened, identified validated ultra-performance liquid chromatography-quadrupole-time flight-mass spectrometry (UPLC-Q-TOF-MS) methods to explore potential biomakers possible metabolic pathways. Untargeted...
Background Hand, foot, and mouth disease (HFMD) is a febrile rash infection caused by enteroviruses, spreading mainly via the respiratory tract close contact. In past two decades, HFMD has been prevalent in Asia, including China South Korea, causing huge burden putting lives health of children at risk. Therefore, further study factors influencing incidences far-reaching implications. existing studies, environmental affecting such are divided into categories: meteorological air. Among these...
Naja atra bite is one of the most common severe snakebites in emergency departments. Unfortunately, pathophysiological changes caused by are unclear due to lack good animal models. In this study, an model Guangxi Bama miniature pigs was established intramuscular injection at 2 mg/kg venom, and serum metabolites were systematically analyzed using untargeted metabolomic targeted approaches. Untargeted analysis revealed that 5045 chromatographic peaks obtained ESI+ 3871 ESI-. Screening modes...
Most patients with advanced leukemia eventually die from multidrug resistance (MDR). Chemotherapy-resistant cells may lead to treatment failure and disease relapse. Overexpression of ATP-binding cassette subfamily G member 2 (ABCG2) leads MDR, which serves as a potential biomarker target therapeutic intervention for cells. Targeting ABCG2 is strategy selective therapy eradicate MDR cells, thus improving malignant treatment. KD025 (SLx-2119) novel Rho-associated protein kinase 2-selective...
Background: Bungarus multicinctus is one of the most dangerous venomous snakes prone to cardiopulmonary damage with extremely high mortality. In our previous work, we found that glutamine (Gln) and synthetase (GS) in pig serum were significantly reduced after bite. present study, explore whether there a link between pathogenesis injury Gln metabolic changes induced by venom. We investigated effect supplementation on lung heart function snakebite. Methods: supplemented different...
The present study aims to investigate the clinical efficacy of recombinant human growth hormone (r-hGH) in treatment school-age pediatric patients with idiopathic short stature (ISS). Pediatric who were diagnosed ISS and treated r-hGH at our hospital enrolled as research subjects. main outcome indicators included serum level insulin-like factor-1, factor binding protein-3, baseline height standard deviation scores, posttreatment scores retrospective analysis was performed. This complies...
Objective To investigate the preemptive analgesia effects of tramadol on stress reaction during in patients undergoing laparoscopic hiatus hernia surgery. Methods Conduct prospective studying sixty surgery Xinjang Uygur Autonomous Region People′s Hospital from June to December 2016.All were randomly divided into three groups with 20 each by double-blind design method.Tramadol group(group A): received 2.5 mg/kg intravenously 30 min before operation and 2 ml saline at end operation;...