- Plant Pathogens and Fungal Diseases
- Gastroesophageal reflux and treatments
- Helicobacter pylori-related gastroenterology studies
- Gastric Cancer Management and Outcomes
- Mycotoxins in Agriculture and Food
- Mycorrhizal Fungi and Plant Interactions
- Yeasts and Rust Fungi Studies
- Plant-Microbe Interactions and Immunity
- Eosinophilic Esophagitis
- Metastasis and carcinoma case studies
- Gastrointestinal Tumor Research and Treatment
- Gastrointestinal disorders and treatments
- Plant Disease Resistance and Genetics
- Esophageal Cancer Research and Treatment
- Plant Virus Research Studies
- Plant Pathogens and Resistance
- Esophageal and GI Pathology
- Plant and Fungal Interactions Research
- Gastrointestinal motility and disorders
- Plant Disease Management Techniques
- Vasculitis and related conditions
- Microbial Natural Products and Biosynthesis
- Microbial Metabolites in Food Biotechnology
- Vascular Anomalies and Treatments
- Leech Biology and Applications
Kyushu Okinawa Agricultural Research Center
2022-2025
National Agriculture and Food Research Organization
2011-2023
Institute for Sustainable Plant Protection
2023
Agricultural Research Center
2011-2023
Institute of Vegetable and Floriculture Science
2020-2021
Toyama Prefectural Agricultural, Forestry & Fisheries Research Center
2019
Central Region Agricultural Research Center
2010-2014
Juntendo University Nerima Hospital
2011-2014
Juntendo University
1998-2011
Washington State University
2011
Goals To investigate the features of nonerosive reflux disease (NERD). Background NERD is not considered as a milder form erosive gastro-esophageal (eGERD). Although prevalence was reported to be high in our country, there have been very few studies about NERD. Study We performed upper gastrointestinal endoscopy confirm diagnosis GERD. The modified acid perfusion test and saline were 7 control subjects, 14 NERD, 11 eGERD patients. stimulus-response function quantified by duration typical...
Fusarium oxysporum is an ascomycetous fungus that well-known as a soilborne plant pathogen. In addition, large population of nonpathogenic F. (NPF) inhabits various environmental niches, including the phytosphere. To obtain insight into origin pathogenic oxysporum, we focused on tomato (Solanum lycopersicum) and its f. sp. lycopersici (FOL). We collected from wild transition Solanum spp. modern cultivars in Chile, Ecuador, Peru, Mexico, Afghanistan, Italy, Japan, evaluated fungal isolates...
ABSTRACT Sweet potato foot rot, caused by Diaporthe destruens , has been recently reported in various regions Japan. To investigate genetic diversity of D. within Japan, 135 isolates were collected 12 prefectures and ITS, TUB, TEF, H3 CAL sequenced. In all regions, there was no difference sequence among isolates, implying high homogeneity the fungus spread A phylogenetic tree constructed for ITS with other strains registered NCBI database. tree, our samples positioned closely to Korea China...
Recent studies have shown the correlation between vertebral fractures (VFs) and gastrointestinal disorders in postmenopausal women. The aim of this study was to assess association VFs hiatal hernia (HH) and/or reflux esophagitis (RE) our patient population both men women.We analyzed retrospective data 280 patients aged 60 years or older (140 140 women, mean +/- SD 73.5 +/-7.05) who had undergone upper endoscopy chest X-rays hospital from August 2005 February 2006. We presence HH RE.The...
Although many factors that may affect the 13C-urea value have been verified, no literature is available regarding effect of posture patient on shape delta 13C excretion curve. In an effort to contribute development a simple and standard procedure for breath test, we investigated whether either during or mouthwash after dosing affects curve.Seventy-two Helicobacter pylori-infected subjects were divided into four groups according position dosing: group A, in supine with mouthwash; B, sitting...
Sexual reproduction in heterothallic ascomycete fungi is controlled by a single mating-type locus called MAT1 with two alternate alleles or idiomorphs, MAT1-1 and MAT1-2. These lack sequence similarity encode different transcriptional regulators. A large number of phytopathogenic including Alternaria spp. are considered asexual, yet still carry expressed genes. The molecular evolution was explored using nucleotide diversity, nonsynonymous vs. synonymous substitution (dn/ds) ratios codon...
Abstract Background and Aims: It is still controversial which drugs, proton pump inhibitors (PPI) or histamine‐2 receptor antagonists (H2RA), are more effective for dyspepsia in the Japanese population. Methods: Patients with uninvestigated ( n = 104; male/female 41/63) were treated either rabeprazole 10 mg o.d. 62) lafutidine b.i.d. 42) 4 weeks. Questionnaires (modified Frequency Scale Symptoms of Gastroesophageal Reflux Disease [mFSSG] quality life [QOL], SF‐8) administered before after...
A spontaneous non-pathogenic variant (Cong:1-2) derived from Fusarium oxysporum f. sp. conglutinans (Cong: 1-1), a causal agent of cabbage yellows, carries biocontrol activity for yellows. We found GMC oxidoreductase (ODX1) among the proteins expressed much more in Cong:1-2 than Cong:1-1 by 2D-DIGE comparison. oxidoreductases have been reported to be involved several plant pathogenic fungi. The gene encoding ODX1 was cloned, and targeted disruption did not affect its activity, suggesting...
Wegener's granulomatosis (WG) is a multisystemic disease of unknown etiology characterized by necrotizing vasculitis and granulomatous inflammation (1-3). The typically involves the upper airways, lungs kidneys, gastrointestinal involvement uncommon. Described here 33-year-old man who presented at hospital with abdominal pain. Colonoscopy revealed multiple ulcers, including round throughout large intestine. Small bowel ulcers were detected double balloon enteroscopy (DBE). Further study...
Fusarium root rot of lisianthus (Eustoma grandiflorum) caused by solani is one the most important and damaging diseases. It occurs commonly in Japan worldwide causes serious crop losses. However, little effort has been made to breed for resistance this disease. We initiated a breeding program F. 2014. Twenty-nine cultivars (E. inbred line Eustoma exaltatum were evaluated two isolates (MAFF712388 MAFF712411) solani, as first step toward resistant cultivars. Seedlings inoculated following...
Abstract Background and Aims: Identifying the invasive depth of cancers less than 10 mm in diameter remains a challenge. This study examines clinicopathological characteristics colorectal invading submucosal layer (SM)3 below, which require surgery must never be treated by endoscopic mucosal resection. Methods: We studied 54 cases cancer submucosa deeper tissues, dividing them into two groups: those SM1 SM2 versus SM3 below. investigated below comparing with SM2. Similarly, 38 cases, whose...
White rust caused by Puccinia horiana Henn. adversely affects chrysanthemum (Chrysanthemum morifolium Ramat.) production. The breeding of resistant varieties is effective in controlling the disease. Here we aimed to develop DNA markers for strong resistance P. horiana. We conducted a linkage analysis based on genome-wide association study (GWAS) method. employed biparental population GWAS, wherein single nucleotide polymorphism (SNP) allele frequency could be predicted. was derived from...
A nonpathogenic mutant (REMI10) of Fusarium oxysporum f. sp. conglutinans (FOC) was generated by restriction enzyme-mediated integration (REMI). REMI10 penetrated the cabbage root cortex much slower than FOC and never invaded xylem through endodermis. Previous treatment seedlings with reduced disease incidence yellows caused FOC, suggesting that has biocontrol activity. invasion into tissues restricted when seedling treated REMI10. The gene disrupted in genome plasmid insertion identified,...