Pei Xu

ORCID: 0000-0003-3268-6839
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About
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Research Areas
  • Ovarian function and disorders
  • Reproductive Biology and Fertility
  • Insect Resistance and Genetics
  • Birth, Development, and Health
  • Endometriosis Research and Treatment
  • Ovarian cancer diagnosis and treatment
  • Thyroid Disorders and Treatments
  • Entomopathogenic Microorganisms in Pest Control
  • Genetic Syndromes and Imprinting
  • Cardiovascular Disease and Adiposity
  • Thyroid Cancer Diagnosis and Treatment
  • Lymphoma Diagnosis and Treatment
  • Wound Healing and Treatments
  • RNA Research and Splicing
  • Estrogen and related hormone effects
  • Maternal and fetal healthcare
  • Surgical Sutures and Adhesives
  • Nuclear Receptors and Signaling
  • Hormonal and reproductive studies
  • Connective tissue disorders research
  • Pregnancy and preeclampsia studies
  • Sexual Differentiation and Disorders
  • Insect symbiosis and bacterial influences
  • Vitamin D Research Studies
  • Molecular Biology Techniques and Applications

Ningbo No. 2 Hospital
2025

Hubei University
2022-2023

Guangzhou Medical University
2018-2021

Third Affiliated Hospital of Guangzhou Medical University
2017-2021

China Medical University
2021

Nanjing University
2009-2015

Nanjing Medical University
2013

Successful pregnancy involves the homeostasis between maternal decidua and fetoplacental units, whose disruption contributes to compromised outcomes, including recurrent spontaneous abortion (RSA). The role of cell heterogeneity in RSA is yet be illustrated.A total 66,078 single cells from samples isolated patients with healthy controls were analysed by unbiased single-cell RNA sequencing (scRNA-seq).Our scRNA-seq results revealed that stromal are most abundant type during early pregnancy....

10.1111/cpr.13125 article EN cc-by Cell Proliferation 2021-09-21

Women with obesity usually need larger doses of FSH for ovarian stimulation, resulting in poor outcomes; however, the mechanism is still unclear. To investigate molecular regulation receptor (FSHR) expression associated obesity. Case-control study to improve vitro fertilization (IVF) outcomes. (82) and women who were overweight (457) undergoing IVF 1790 age-matched controls normal weight from our reproductive medicine center. FSHR was decreased parallel body mass index (BMI), whereas...

10.1210/jc.2018-00686 article EN The Journal of Clinical Endocrinology & Metabolism 2018-11-21

Plagiodera versicolora (Coleoptera: Chrysomelidae) is one of the most destructive pests Salicaceae worldwide, which has established complex interactions with surrounding organisms. Uncovering molecular mechanisms some antagonistic would facilitate development environmentally friendly pest insect management strategies. Suitable reference genes are essential for reliable qPCR and gene expression analysis in studies; however, a comprehensive assessment P. still lacking. In this study, stability...

10.3390/agronomy12051192 article EN cc-by Agronomy 2022-05-15

The relationship between metabolic risk and ovarian function is ambiguous. This retrospective study analyzed the medical records of 461 PCOS patients collected January 2019 June 2020 to investigate serum anti-Müllerian hormone (AMH) parameters in population with polycystic ovary syndrome (PCOS). A total aged 20-40 years were included stratified into four groups according AMH level. association related these was compared, discrepancies further explored. Binary logistic regression performed...

10.1155/2021/9511772 article EN cc-by International Journal of Endocrinology 2021-08-12

Background Thyroid function can be influenced by external stimuli such as light and temperature. However, it is currently unknown whether there seasonal variation of thyroid in women reproductive age. Adequate reproductive-aged necessary for optimal fetal–maternal outcomes. Therefore, this study aims to evaluate the changes levels thyrotropin (TSH), free triiodothyronine (FT 3 ), thyroxine 4 TSH index (TSHI) Methods A large retrospective was conducted that included aged 20–49 years who...

10.3389/fendo.2021.719225 article EN cc-by Frontiers in Endocrinology 2021-09-02

The differential steroid production in the theca and granulosa cells ovary are resulted from unique enzyme expression profiles. Among them, c-fos, a downstream target of mitogen extracellular signal-regulated kinases (MEK/ERK) signaling, takes part this compartment. In study, we investigated effect c-fos on steady-state levels CYP17 CYP19 human ovarian granulosa-like tumor cell line (KGN) by inhibiting MEK/ERK pathway with PD98059. As result, our finding demonstrated distinct distribution...

10.3109/09513590.2015.1106470 article EN Gynecological Endocrinology 2015-11-03

This research investigated the response of vascular active factors, endothelial growth factor (VEGF) and angiotensin-II (AT-II) to ovarian stimulation during 24 hours in patients with polycystic ovary syndrome (PCOS).In this clinical trial study, 52 PCOS 8 control cases were stimulated human chorionic gonadotropin (HCG) on 4(th) 7(th) day patients' natural or induced menstrual cycles. We measured VEGF AT-II by radioimmunoassay before injection (0 hour) 3, 8, 12, 18 after stimulation.After...

10.22074/ijfs.2015.4176 article EN DOAJ (DOAJ: Directory of Open Access Journals) 2015-03-18

The entomopathogenic fungus is recognized as an ideal alternative to chemical pesticides, nonetheless, its efficacy often limited by insect’s innate immune system. suppression of the host immunity may overcome obstacle and promote toxicity fungi. Here, using Beauveria bassiana genes dsRNA-expressing bacteria, we explored potentially synergistic two agents on a leaf beetle Plagiodera versicolora (Coleoptera: Chrysomelidae). We first determined susceptibilities P. B. 476 strain (hereafter...

10.2139/ssrn.4358004 article EN 2023-01-01

Objective 21-hydroxylase deficiency (21-OHD) and 17α-hydroxylase (17-OHD) are two types of congenital adrenal hyperplasia (CAH). There different subtypes according to the degree hydroxylase various clinical characteristics, which non-classical 21-hydroxylase incomplete show mild characteristics. The rate pregnancy with 21-OHD 17-OHD moderately reduced when compared normal adult women. How improve outcome fertility our key points. Methods This paper attached a report client in...

10.3760/cma.j.issn.2096-2916.2017.10.011 article EN Chin J Reprod Contracep 2017-10-25
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