- Animal health and immunology
- Microbial infections and disease research
- Viral gastroenteritis research and epidemiology
- Effects of Environmental Stressors on Livestock
- Reproductive Physiology in Livestock
- Cardiac Arrest and Resuscitation
- Genetic and phenotypic traits in livestock
- Mechanical Circulatory Support Devices
- Congenital Anomalies and Fetal Surgery
- Ultrasound in Clinical Applications
- Gastrointestinal disorders and treatments
- Veterinary Pharmacology and Anesthesia
- Vector-Borne Animal Diseases
- Spinal Dysraphism and Malformations
- Veterinary Orthopedics and Neurology
- Veterinary Oncology Research
- Veterinary Equine Medical Research
- Congenital Diaphragmatic Hernia Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Antibiotics Pharmacokinetics and Efficacy
- Veterinary Practice and Education Studies
- Animal Virus Infections Studies
- Cardiac Ischemia and Reperfusion
- Anesthesia and Sedative Agents
- Neurological diseases and metabolism
University of Milan
2015-2025
University of Veterinary Medicine
2022
Ospedale Maggiore di Lodi
2010-2018
Justus-Liebig-Universität Gießen
2003-2004
Background Mechanical chest compression (CC) is currently suggested to deliver sustained high-quality CC in a moving ambulance. This study compared the hemodynamic support provided by mechanical piston device or manual during ambulance transport porcine model of cardiopulmonary resuscitation. Methods and Results In simulated urban transport, 16 pigs cardiac arrest were randomized 18 minutes with LUCAS (n=8) (n=8). ECG, arterial right atrial pressure, together end-tidal CO
The cows receiving antibiotics for intra-mammary infection (IMI) produce milk that cannot be marketed. This is considered waste (WM), and a convenient option farmers using it as calf food. However, adding to the risk of selecting resistant bacteria, residual might interfere with gut microbiome development influence gastrointestinal health. We assessed longitudinal effect unpasteurized WM containing cefalexin on intestinal health fecal microbiota in an 8-week trial. After 3 days colostrum,...
Both condensed and hydrolysable tannins (CTs HTs, respectively) have the ability to reduce enteric CH 4 production in ruminants. However, precise mechanism of action is not fully understood. Among proposed hypotheses are reduction ruminal digestibility, direct control on protozoa, archaea, a hydrogen sink mechanism. In this vitro study, which simulated rumen fermentation, two additives, one containing CTs (70% based DM) from quebracho with HTs (75% chestnut, at four levels inclusion (2, 4,...
Abstract Background Bronchopneumonia (BP) in calves potentially causes systemic changes. Objectives To describe metabolic, arterial blood gas, and acid‐base disorders with BP diagnosed by thoracic ultrasound (TUS), Wisconsin score (WISC), combinations of WISC TUS. Animals Two hundred thirty‐one dairy preweaned from 13 farms. Methods Cross‐sectional study. Each calf sequentially underwent gas evaluation, score, venous sampling, Calves were grouped based on a single diagnostic method...
Abstract South American Camelids, including alpacas, have gained popularity in Europe as pets and prized wool sources. Skin health concerns, particularly mite infestations, emerged a notable problem these animals. Sarcoptic mange can lead to severe itching, papules, chronic symptoms such alopecia, crusts, emaciation if left untreated. This case report documents 2-year-old female alpaca suffering from sarcoptic mange. Despite initial treatment with ivermectin, its condition worsened, leading...
ABSTRACT Background Bronchopneumonia (BP) can cause pulmonary hypertension (PH) and secondary cardiovascular changes. Objectives The aim of this study was to describe PH–related transthoracic Doppler echocardiography (TTE) changes in preweaned dairy calves with BP diagnosed by thoracic ultrasonography (TUS). Animals One hundred sixty‐four were selected from 11 commercial farms. Methods This is a case–control study. enrolled grouped according TUS results into either the control group (with...
Bovine respiratory disease (BRD) poses a significant risk of morbidity and mortality in preweaned dairy calves. Research indicates that this multifactorial disorder can be attributed to the involvement various pathogens. Currently, there is little information from genome-wide association studies (GWAS) for BRD resistance young calves based on objective measures classification disease. In study, we moved forward phenotyping by coupling two diagnostic tests, thoracic ultrasonography (TUS)...
Bacteremia is a potential systemic complication of bronchopneumonia (BP) in dairy calves, which increases the risk sepsis and mortality. However, data on bacteremia farm conditions still limited. This study investigates prevalence calves with BP farms, examining isolated pathogens associations between thoracic ultrasonography (TUS) non-endoscopic bronchoalveolar lavage (nBAL) findings. The enclosed 13 farms included 211 eligible preweaned 88 were diagnosed based highly sensitive threshold ≥...
Hazelnut skins (HS) are usually managed as waste; however, this by-product is a source of bioactive compounds, with potential applications in feed and food sectors. Phenolic compounds can be extracted using green protocols combining enabling technologies solvents. This work investigates subcritical water extraction (SWE) from HS. A laboratory-scale study was performed on four different batches, significant batch-to-batch heterogeneity. The evaluation polyphenolic profiles antioxidant...
ABSTRACT Introduction: The study investigated the effect of untreated cardiac arrest (CA), that is, “no-flow” time, on postresuscitation myocardial and neurological injury, survival in a pig model to identify an optimal duration adequately reflects most frequent clinical scenario. Methods: An established infarction followed by CA cardiopulmonary resuscitation was used. Twenty-two pigs were subjected three no-flow durations: short (8–10 min), intermediate (12–13 long (14–15 min). Left...
Background Ventilation with the noble gas argon (Ar) has shown neuroprotective and cardioprotective properties in different vitro vivo models. Hence, effects of Ar were investigated a severe, preclinically relevant porcine model cardiac arrest. Methods Results Cardiac arrest was ischemically induced 36 pigs left untreated for 12 minutes before starting cardiopulmonary resuscitation. Animals randomized to 4-hour post-resuscitation ventilation with: 70% nitrogen-30% oxygen (control); 50%...
The conjugated linoleic acid (CLA) isomers, a group of naturally occurring isomers the essential fatty (FA) acid, have received special attention in animal and human nutrition. Although they long been used as dietary integrators dairy cows, effects CLA on bovine immune cells remain mostly undisclosed. present study aimed to cover this gap investigate vitro inflammatory functions, including chemotaxis, phagocytosis, killing capability, extracellular respiratory burst purified monocytes...
Abstract Background Although thoracic auscultation (AUSC) in calves is quick and easy to perform, the definition of lung sounds highly variable leads poor moderate accuracy diagnosing bronchopneumonia (BP). Hypothesis/Objectives Evaluate diagnostic an AUSC scoring system based on a standard sound nomenclature at different cut‐off values, accounting for absence gold test BP diagnosis. Animals Three hundred thirty‐one calves. Methods We considered following pathological sounds: increased...
Abstract Objective —To determine the correlation between insulin concentrations and myoelectrical activity of abomasum in cows with a left displaced (LDA). Animals —14 dairy an LDA at onset lactation. Procedure —During surgical correction LDA, 3 pairs electrodes were placed smooth muscle gastrointestinal tract (abomasal body, pars pylorica, duodenum) each cow. Electromyographic recordings obtained once per day for 7 days. Samples collected tested to insulin, glucagon, cortisol, glucose,...
To evaluate the pharmacokinetics of dexmedetomidine (DEX) administered I/V at a dose 5 µg/kg bodyweight in dairy calves and to compare sedative effects anaesthetic protocols involving DEX xylazine.Nine calves, aged 17-20 days, were treated with dexmedetomidine. For pharmacokinetic evaluation, blood samples collected over 12 hours serum analysed by high performance liquid chromatography-mass spectrometry. Another nine 16-20 0.2 mg/kg xylazine. After both treatments, heart rate, respiratory...
The features of a calf with split cord malformation are described. Clinically, there was severe cervicothoracic kyphoscoliosis and an interscapular dermal sinus associated cerebrospinal fluid drainage. Using magnetic resonance imaging, complete duplication the spinal at cervical intumescence detected. There syringohydromyelia, multiple vertebral malformations resulting in rachischisis, herniation cerebellar vermis, meningoencephalocele, calvarial defects.
To report clinical signs, diagnostic and surgical or necropsy findings, outcome in 2 calves with spinal epidural abscess (SEA).Clinical report.Calves (n=2).Calves had neurologic examination, analysis antimicrobial culture of cerebrospinal fluid (CSF), vertebral column radiographs, myelography, 1 calf, magnetic resonance imaging (MRI). A definitive diagnosis SEA was confirmed by calf during surgery histologic examination canal tissue calf.Clinical signs were difficulty rising, ataxia, fever,...
To evaluate the effects of storage conditions on total protein (TP) and globulin fractions in fresh frozen bovine plasma units prepared stored for transfusion, TP were evaluated at 1 month 6 12 months after blood collection -20°C. Significant differences concentrations found median concentration (P=0.0336), between 0 (P=0.0108), (P=0.0023), (P=0.0027), mean (g/dL) albumin (P=0.0394), (P=0.0131), (P=0.0035), (P=0.0038), beta-2 fraction (P=0.0401), (P=0.0401) (P=0.0230). This study suggests...
The clinical and pathologic findings related to an infiltrative facial lipoma in a 5‐month‐old female Holstein Friesian calf are reported. tumor was congenital, increased size with time, deformed the left side of face cranial bones. condition good; only detectable abnormalities were poor weight gain decreased motility upper lip. Clinical radiologic data indicated mass not removable. Muscle lymph node invasion by tissue detected histologically. Infiltrative is rare variety that has been...
Radioimmunoassay (RIA) is the “gold standard” method for evaluation of serum cortisol concentration. The VIDAS test an enzyme‐linked fluorescent assay designed MiniVidas system. aim this study was to compare with RIA measurement bovine Cortisol concentrations were evaluated in 40 cows using both and methods, latter as reference method. A paired Student’s t ‐test, Pearson’s correlation analysis, Bland‐Altman plot, Deming regression analysis used two methods. There no statistically significant...