A5100668999- Plant Molecular Biology Research
- Plant Gene Expression Analysis
- Plant Physiology and Cultivation Studies
- Plant biochemistry and biosynthesis
- Tryptophan and brain disorders
- Phytochemicals and Antioxidant Activities
- Genetic Associations and Epidemiology
- Plant tissue culture and regeneration
- Plant Reproductive Biology
- Genetics and Neurodevelopmental Disorders
- 14-3-3 protein interactions
- Plant Virus Research Studies
- Horticultural and Viticultural Research
- Soybean genetics and cultivation
- Protease and Inhibitor Mechanisms
- Plant Micronutrient Interactions and Effects
- RNA Interference and Gene Delivery
- Microbial Metabolism and Applications
- Protein Structure and Dynamics
- Kruppel-like factors research
- Research in Cotton Cultivation
- Mesenchymal stem cell research
- Reproductive Biology and Fertility
- Aquaculture disease management and microbiota
- Congenital heart defects research
Northwest A&F University
2022-2024
Yangzhou University
2009-2022
Chinese University of Hong Kong, Shenzhen
2021
Shenzhen Research Institute of Big Data
2021
Jilin University
2003-2019
Union Hospital
2019
Ningxia Medical University
2012-2017
Ningxia Medical University General Hospital
2012-2017
Tongji Hospital
2016
Tongji University
2016
Summary The anthocyanin content increases in Malus spectabilis leaves under low‐nitrogen conditions. Noncoding RNAs are indicated to play key regulatory roles biosynthesis. However, the functional of noncoding biosynthesis conditions remain elusive. In this study, miR858 was screened as a regulator through whole‐transcriptome sequencing. Then, we used an entry point explore network lncRNA–miRNA–mRNA by dual‐luciferase reporter assays and GUS histochemical staining assays, well identify...
Singapore grouper iridovirus (SGIV) is a devastating aquaculture virus responsible for heavy economic losses to grouper, Epinephelus sp. aquaculture. The aim of this study was develop rapid and sensitive detection method SGIV infections in infected groupers.We previously generated DNA aptamers against SGIV-infected cells. In study, we established characterized novel aptamer (Q3)-based enzyme-linked apta-sorbent assay (ELASA) the infection coioides. Q3-based ELASA could detect rapidly vitro...
Increasing evidence suggests that aberrant expression of certain microRNAs (miRNAs) may participate in the genesis and progression tumors. Several studies have indicated miR-1247-5p plays different roles various types cancer cells. The effects on human hepatocellular carcinoma (HCC) cells are elusive. In present study, we investigated HCC. transcript was markedly downregulated clinical samples patients with HCC cell lines, ectopic overexpression miR‑1247-5p inhibited proliferation invasion...
The "Spring-red-leaf" crabapple cultivar has young red leaves and mature green leaves. However, the mechanism of anthocyanin biosynthesis in spring remains unknown. In this study, Illumina RNA sequencing (RNA-Seq) was performed on Malus 'Radiant' leaf tissues different stages development. Twenty-two genes pathway 44 MYB transcription factors (TFs) were significantly enriched among differentially expressed (DEGs). Three R2R3-MYB TFs subgroup 22 TF family, MrMYB44-like1, MrMYB44-like2,...
Atherosclerosis (AS) is a disease induced by multiple factors, including genetic and environmental elements. The aim of the present study to investigate comprehensive effects high cholesterol, methionine diet, apolipoprotein E deficiency (ApoE(-/-)) on pathogenesis AS. ApoE(-/-) mice were fed with cholesterol diet for 15 weeks induce hyperlipidemia hyperhomocysteinemia. methylation levels genomic DNA (gDNA) B1 repetitive elements in aortic tissues measured both methylation-dependent...
Intracranial hemorrhage remains the most feared complication in tissue plasminogen activator (tPA) thrombolysis for ischemic stroke. However, underlying molecular mechanisms are still poorly elucidated. In this study, we reported an important role of caveolin-1 (Cav-1) s-nitrosylation matrix metalloproteinase (MMP)-2 and 9 secretion from tPA-treated endothelial cells. Brain vascular cells (bEND3) were exposed to oxygen-glucose deprivation (OGD) 2 h before adding recombinant human tPA 6 h....
Crabapple is a valuable tree species in gardens due to its captivating array of flower and leaf colors, rendering it favored choice landscaping. The economic ornamental values Malus crabapple are closely associated with the biosynthesis anthocyanin, pigment responsible for vibrant hues. intricate regulation anthocyanin involves concerted activity various genes. However, specific mechanism governing this process warrants in-depth exploration. In study, we explored inhibitory role MsMYB62-like...
Watercore is a physiological disorder that commonly occurs in sand pear cultivars. The typical symptom of watercore tissue transparency, and it often accompanied by browning, breakdown bitter taste during fruit ripening. To better understand the molecular mechanisms affecting quality, this study performed transcriptome metabolome analyses on pulp from “Akibae” 125 days after flowering. present found contained higher sorbitol sucrose than healthy fruit. Moreover, structure cell wall was...
C-type lysozyme genes (Lyzls) belong to the class of lysozymes and are highly expressed in testis epididymis.The members Lyzl4 Spaca3 have been reported play a role sperm-egg binding fertilisation mice.However, function remaining two mouse c-type genes, Lyzl1 Lyzl6, is still not clear.In present study, we analysed tissue expression androgen-dependent possible contribution human recombinant LYZL6 (rLYZL6) immunity.The Lyzls was detected by RT-PCR, Western blots, immunohistochemistry...
The somatic embryo (SE) has bipolar characteristics, which is an ideal material for large-scale microproduction of woody plants represented by apples, and the also excellent receptor genetic transformation. formation embryogenic cells a prerequisite embryogenesis to occur. apples cannot be obtained without induction exogenous auxin, but how auxin pathway regulates this process remains unknown. In study, via RNA sequencing,
Drought is an important factor that affects plant anthocyanin biosynthesis. However, the underlying molecular mechanisms remain elusive. Ethylene response factors (ERFs) are pivotal regulators in growth and environmental responses, particularly This study investigated leaf colour transition from green to red Malus spectabilis under drought conditions. was primarily attributed accumulation of anthocyanins, specifically cyanidin-3,5-diglucoside cyanidin-3-O-galactoside. Our findings elucidate...