A5050147819- Cardiac Ischemia and Reperfusion
- Hormonal Regulation and Hypertension
- Adipose Tissue and Metabolism
- Cardiac Fibrosis and Remodeling
- Antiplatelet Therapy and Cardiovascular Diseases
- Acute Myocardial Infarction Research
- Ion Transport and Channel Regulation
- Voice and Speech Disorders
- Blood Pressure and Hypertension Studies
- Respiratory and Cough-Related Research
- Peroxisome Proliferator-Activated Receptors
- Esophageal Cancer Research and Treatment
- Cancer Immunotherapy and Biomarkers
- Organ Transplantation Techniques and Outcomes
- Sodium Intake and Health
- Cardiac and Coronary Surgery Techniques
- Liver physiology and pathology
- Acute Kidney Injury Research
- Nitric Oxide and Endothelin Effects
- Traumatic Brain Injury and Neurovascular Disturbances
- Heme Oxygenase-1 and Carbon Monoxide
- Signaling Pathways in Disease
- Drug-Induced Hepatotoxicity and Protection
- Dysphagia Assessment and Management
- Inflammatory Biomarkers in Disease Prognosis
Army Medical University
2016-2025
Daping Hospital
2016-2025
University of Science and Technology of China
2024
Irisin protects against ischemia/reperfusion injury to the lung by improving mitochondrial function.
Cardiac hypertrophy is accompanied by increased myocardial oxidative stress, and whether naringenin, a natural antioxidant, effective in the therapy of cardiac remains unknown. In present study, different dosage regimens (25, 50, 100 mg/kg/d for three weeks) naringenin (NAR) were orally gavaged an isoprenaline (ISO) (7.5mg/kg)-induced hypertrophic C57BL/6J mouse model. The administration ISO led to significant hypertrophy, which was alleviated pretreatment with both vivo vitro experiments....
Abstract Acute myocardial infarction (MI) is one of the leading causes death in humans. Our previous studies showed that gastrin alleviated acute ischaemia–reperfusion injury. We hypothesize might protect against heart injury after MI by promoting angiogenesis. An model was simulated ligating anterior descending coronary artery adult male C57BL/6J mice. Gastrin administered twice daily intraperitoneal injection for 2 weeks MI. found reduced mortality, improved function with infarct size and...
Background: Genetic variants of coding genes related to blood pressure regulation participate in the pathogenesis hypertension and determines response specific antihypertensive drugs. G protein-coupled receptor kinase 4 (GRK4) its are great importance hypertension. However, little is known about role GRK4 determine circadian rhythm candesartan The aim this study was analyze correlation pressure, explore their effect on efficiency candestartan.Methods: In study, a total 1239 cases were...
Dopamine, via its receptors, plays a vital role in the maintenance of blood pressure by modulating renal sodium transport. However, D4 dopamine receptor (D4 receptor) proximal tubules (PRTs) is still unclear. This study aimed to verify hypothesis that activation directly inhibits activity Na+-K+-ATPase (NKA) RPT cells.NKA activity, nitric oxide (NO) and cyclic guanosine monophosphate (cGMP) levels were measured cells treated with agonist PD168077 and/or antagonist L745870, NO synthase...
Chronic cough after pulmonary resection is one of the most common complications, which seriously affects quality life patients surgery. Therefore, aim this study to explore risk factors chronic and construct a prediction model.
<title>Abstract</title> Objective This study evaluates the prognostic value of preoperative inflammatory markers—Neutrophil-to-Lymphocyte Ratio (NLR), Platelet-to-Lymphocyte (PLR), Systemic Immune-Inflammation Index (SII), and Fibrinogen-to-Prealbumin (FPR)—in patients with resectable esophageal squamous cell carcinoma (ESCC). A survival model integrating these markers TNM staging was developed validated. Methods Clinical data from 224 ESCC who underwent surgical resection between January...
To compare the immediate, early, and delayed percutaneous coronary intervention (PCI) strategies in non-ST-segment-elevation myocardial infarction (NSTEMI) patients with high-risk.
Background Oral NaCl produces a greater natriuresis and diuresis than the intravenous infusion of same amount NaCl, indicating existence gastro-renal axis. As one major natriuretic hormones secreted by both intestines kidney, we hypothesized that renal uroguanylin interacts with dopamine receptors to increase sodium excretion synergistically, an impaired interaction which may be involved in pathogenesis hypertension. Methods Results In Wistar-Kyoto rats, or fenoldopam (a D1-like receptor...